4V6D
 
 | | Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Zhang, W, Dunkle, J.A, Cate, J.H.D. | | Deposit date: | 2009-06-27 | | Release date: | 2014-07-09 | | Last modified: | 2014-12-10 | | Method: | X-RAY DIFFRACTION (3.814 Å) | | Cite: | Structures of the ribosome in intermediate States of ratcheting.
Science, 325, 2009
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4V6C
 | | Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Zhang, W, Dunkle, J.A, Cate, J.H.D. | | Deposit date: | 2009-06-27 | | Release date: | 2014-07-09 | | Last modified: | 2014-12-10 | | Method: | X-RAY DIFFRACTION (3.19 Å) | | Cite: | Structures of the ribosome in intermediate States of ratcheting.
Science, 325, 2009
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4V6E
 | | Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Zhang, W, Dunkle, J.A, Cate, J.H.D. | | Deposit date: | 2009-06-28 | | Release date: | 2014-07-09 | | Last modified: | 2014-12-10 | | Method: | X-RAY DIFFRACTION (3.712 Å) | | Cite: | Structures of the ribosome in intermediate States of ratcheting.
Science, 325, 2009
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1P58
 | | Complex Organization of Dengue Virus Membrane Proteins as Revealed by 9.5 Angstrom Cryo-EM reconstruction | | Descriptor: | Envelope protein M, Major envelope protein E | | Authors: | Zhang, W, Chipman, P.R, Corver, J, Johnson, P.R, Zhang, Y, Mukhopadhyay, S, Baker, T.S, Strauss, J.H, Rossmann, M.G, Kuhn, R.J. | | Deposit date: | 2003-04-25 | | Release date: | 2003-11-04 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (9.5 Å) | | Cite: | Visualization of membrane protein domains by cryo-electron microscopy of dengue virus
Nat.Struct.Biol., 10, 2003
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6FE8
 | | Cryo-EM structure of the core Centromere Binding Factor 3 complex | | Descriptor: | Centromere DNA-binding protein complex CBF3 subunit B, Centromere DNA-binding protein complex CBF3 subunit C, Suppressor of kinetochore protein 1 | | Authors: | Zhang, W.J, Lukoynova, N, Miah, S, Vaughan, C.K. | | Deposit date: | 2017-12-30 | | Release date: | 2018-08-01 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Insights into Centromere DNA Bending Revealed by the Cryo-EM Structure of the Core Centromere Binding Factor 3 with Ndc10.
Cell Rep, 24, 2018
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6GSA
 | | Core Centromere Binding Factor 3 (CBF3) with monomeric Ndc10 | | Descriptor: | Centromere DNA-binding protein complex CBF3 subunit A, Centromere DNA-binding protein complex CBF3 subunit B, Centromere DNA-binding protein complex CBF3 subunit C, ... | | Authors: | Zhang, W.J, Lukoynova, N, Vaughan, C.K. | | Deposit date: | 2018-06-13 | | Release date: | 2018-08-01 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Insights into Centromere DNA Bending Revealed by the Cryo-EM Structure of the Core Centromere Binding Factor 3 with Ndc10.
Cell Rep, 24, 2018
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5CB5
 | | Structural Insights into the Mechanism of Escherichia coli Ymdb | | Descriptor: | ACETATE ION, ADENOSINE-5-DIPHOSPHORIBOSE, O-acetyl-ADP-ribose deacetylase, ... | | Authors: | Zhang, W, Wang, C, Song, Y, Shao, C, Zhang, X, Zang, J. | | Deposit date: | 2015-06-30 | | Release date: | 2015-11-04 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural insights into the mechanism of Escherichia coli YmdB: A 2'-O-acetyl-ADP-ribose deacetylase
J.Struct.Biol., 192, 2015
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5CMS
 | | Structural Insights into the Mechanism of Escherichia coli Ymdb | | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, O-acetyl-ADP-ribose deacetylase, SULFATE ION | | Authors: | Zhang, W, Wang, C, Song, Y, Shao, C, Zhang, X, Zang, J. | | Deposit date: | 2015-07-17 | | Release date: | 2015-11-04 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.98 Å) | | Cite: | Structural insights into the mechanism of Escherichia coli YmdB: A 2'-O-acetyl-ADP-ribose deacetylase
J.Struct.Biol., 192, 2015
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2K9X
 | | Solution structure of Urm1 from Trypanosoma brucei | | Descriptor: | Uncharacterized protein | | Authors: | Zhang, W, Zhang, J, Xu, C, Wang, T, Zhang, X, Tu, X. | | Deposit date: | 2008-10-27 | | Release date: | 2009-03-10 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of Urm1 from Trypanosoma brucei
Proteins, 75, 2009
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6L13
 | | Crystal structure of Ser/Thr kinase Pim1 in complex with 10-DEBC derivatives | | Descriptor: | 2-chloranyl-10-(2-piperidin-4-ylethyl)phenoxazine, Serine/threonine-protein kinase pim-1 | | Authors: | Zhang, W, Xie, Y, Cao, R, Huang, N, Zhou, Y. | | Deposit date: | 2019-09-27 | | Release date: | 2020-05-27 | | Last modified: | 2020-07-08 | | Method: | X-RAY DIFFRACTION (2.24 Å) | | Cite: | Structure-Based Optimization of 10-DEBC Derivatives as Potent and Selective Pim-1 Kinase Inhibitors.
J.Chem.Inf.Model., 60, 2020
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6L14
 | | Crystal structure of Ser/Thr kinase Pim1 in complex with 10-DEBC derivatives | | Descriptor: | 2-chloranyl-10-[3-[(3~{S})-piperidin-3-yl]propyl]phenoxazine, Serine/threonine-protein kinase pim-1 | | Authors: | Zhang, W, Xie, Y, Cao, R, Huang, N, Zhou, Y. | | Deposit date: | 2019-09-27 | | Release date: | 2020-05-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structure-Based Optimization of 10-DEBC Derivatives as Potent and Selective Pim-1 Kinase Inhibitors.
J.Chem.Inf.Model., 60, 2020
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5CB3
 | | Structural Insights into the Mechanism of Escherichia coli Ymdb | | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, O-acetyl-ADP-ribose deacetylase | | Authors: | Zhang, W, Wang, C, Song, Y, Shao, C, Zhang, X, Zang, J. | | Deposit date: | 2015-06-30 | | Release date: | 2015-11-04 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural insights into the mechanism of Escherichia coli YmdB: A 2'-O-acetyl-ADP-ribose deacetylase
J.Struct.Biol., 192, 2015
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2L42
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2L7E
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2L83
 | | A protein from Haloferax volcanii | | Descriptor: | Small archaeal modifier protein 1 | | Authors: | Zhang, W, Liao, S, Fan, K, Tu, X. | | Deposit date: | 2011-01-03 | | Release date: | 2012-01-11 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Ionic strength-dependent conformations of a ubiquitin-like small archaeal modifier protein (SAMP1) from Haloferax volcanii.
Protein Sci., 22, 2013
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4RHD
 | | DNA Duplex with Novel ZP Base Pair | | Descriptor: | DNA 9mer novel P nucleobase, DNA 9mer novel Z nucleobase, MAGNESIUM ION | | Authors: | Zhang, W, Zhang, L, Benner, S, Huang, Z. | | Deposit date: | 2014-10-01 | | Release date: | 2015-07-08 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Evolution of functional six-nucleotide DNA.
J.Am.Chem.Soc., 137, 2015
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6QJP
 | | Cryo-EM structure of heparin-induced 2N4R tau jagged filaments | | Descriptor: | Microtubule-associated protein tau | | Authors: | Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W. | | Deposit date: | 2019-01-24 | | Release date: | 2019-02-20 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
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6QJH
 | | Cryo-EM structure of heparin-induced 2N4R tau snake filaments | | Descriptor: | Microtubule-associated protein tau | | Authors: | Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W. | | Deposit date: | 2019-01-24 | | Release date: | 2019-02-20 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
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6QJM
 | | Cryo-EM structure of heparin-induced 2N4R tau twister filaments | | Descriptor: | Microtubule-associated protein tau | | Authors: | Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W. | | Deposit date: | 2019-01-24 | | Release date: | 2019-02-27 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
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6QJQ
 | | Cryo-EM structure of heparin-induced 2N3R tau filaments | | Descriptor: | Microtubule-associated protein tau | | Authors: | Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W. | | Deposit date: | 2019-01-24 | | Release date: | 2019-02-20 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
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4ACS
 | | Crystal structure of mutant GST A2-2 with enhanced catalytic efficiency with azathioprine | | Descriptor: | GLUTATHIONE, GLUTATHIONE S-TRANSFERASE A2 | | Authors: | Zhang, W, Moden, O, Tars, K, Mannervik, B. | | Deposit date: | 2011-12-19 | | Release date: | 2011-12-28 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure-based redesign of GST A2-2 for enhanced catalytic efficiency with azathioprine.
Chem.Biol., 19, 2012
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5DHC
 | | Cooperativity and Downstream Binding in RNA Replication | | Descriptor: | GUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCA)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*U)-3') | | Authors: | Zhang, W, Fahrenbach, A.C, Tam, C.P, Szostak, J.W. | | Deposit date: | 2015-08-30 | | Release date: | 2016-12-07 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Unusual Base-Pairing Interactions in Monomer-Template Complexes.
ACS Cent Sci, 2, 2016
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4M3Q
 | | Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC1917 | | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Tyrosine-protein kinase Mer, ... | | Authors: | Zhang, W, Zhang, D, Stashko, M.A, DeRyckere, D, Hunter, D, Kireev, D.B, Miley, M, Cummings, C, Lee, M, Norris-Drouin, J, Stewart, W.M, Sather, S, Zhou, Y, Kirkpatrick, G, Machius, M, Janzen, W.P, Earp, H.S, Graham, D.K, Frye, S, Wang, X. | | Deposit date: | 2013-08-06 | | Release date: | 2013-11-27 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.718 Å) | | Cite: | Pseudo-Cyclization through Intramolecular Hydrogen Bond Enables Discovery of Pyridine Substituted Pyrimidines as New Mer Kinase Inhibitors.
J.Med.Chem., 56, 2013
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5KRG
 | | RNA 15mer duplex binding with PZG monomer | | Descriptor: | RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*GP*G)-3'), [(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-(3-methyl-1~{H}-pyrazol-4-yl)phosphinic acid | | Authors: | Zhang, W, Tam, C.P, Szostak, J.W. | | Deposit date: | 2016-07-07 | | Release date: | 2016-12-07 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Unusual Base-Pairing Interactions in Monomer-Template Complexes.
ACS Cent Sci, 2, 2016
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1OR4
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