4ACS
Crystal structure of mutant GST A2-2 with enhanced catalytic efficiency with azathioprine
Summary for 4ACS
| Entry DOI | 10.2210/pdb4acs/pdb |
| Related | 1AGS 2VCT 2WJU |
| Descriptor | GLUTATHIONE S-TRANSFERASE A2, GLUTATHIONE (3 entities in total) |
| Functional Keywords | transferase, oxidation-reduction |
| Biological source | HOMO SAPIENS (HUMAN) |
| Total number of polymer chains | 4 |
| Total formula weight | 103740.24 |
| Authors | Zhang, W.,Moden, O.,Tars, K.,Mannervik, B. (deposition date: 2011-12-19, release date: 2011-12-28, Last modification date: 2023-12-20) |
| Primary citation | Zhang, W.,Moden, O.,Tars, K.,Mannervik, B. Structure-based redesign of GST A2-2 for enhanced catalytic efficiency with azathioprine. Chem.Biol., 19:414-421, 2012 Cited by PubMed: 22444596DOI: 10.1016/j.chembiol.2012.01.021 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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