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PDB: 261 results

4GE2
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Crystal structure of human protein tyrosine phosphatase PTPN9 (MEG2) complex with compound 3
Descriptor: N-acetyl-4-[difluoro(phosphono)methyl]-L-phenylalanyl-N~5~-(3-iodobenzoyl)-L-ornithinamide, Tyrosine-protein phosphatase non-receptor type 9
Authors:Zhang, Z.-Y, Liu, S, Zhang, S.
Deposit date:2012-08-01
Release date:2012-10-31
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A Highly Selective and Potent PTP-MEG2 Inhibitor with Therapeutic Potential for Type 2 Diabetes.
J.Am.Chem.Soc., 134, 2012
4GE5
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Crystal structure of human protein tyrosine phosphatase PTPN9 (MEG2) complex with compound 5
Descriptor: N-(4-bromo-3-methylbenzoyl)-4-[difluoro(phosphono)methyl]-L-phenylalanyl-N~5~-(3-iodobenzoyl)-L-ornithinamide, Tyrosine-protein phosphatase non-receptor type 9
Authors:Zhang, Z.-Y, Liu, S, Zhang, S.
Deposit date:2012-08-01
Release date:2012-10-31
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Highly Selective and Potent PTP-MEG2 Inhibitor with Therapeutic Potential for Type 2 Diabetes.
J.Am.Chem.Soc., 134, 2012
5J87
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Discovery of N-(3-(5-((3-acrylamido-4-(morpholine-4-carbonyl)phenyl)amino)-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-methylphenyl)-4-(tert-butyl)benzamide (CHMFL-BTK-01) as a Highly Selective Irreversible BTK Kinase Inhibitor
Descriptor: N-[3-(5-{[3-(acryloylamino)-4-(morpholine-4-carbonyl)phenyl]amino}-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-methylphenyl]-4-tert-butylbenzamide, Tyrosine-protein kinase BTK
Authors:Yun, C.H, Zhang, S.
Deposit date:2016-04-07
Release date:2017-04-19
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Discovery of N-(3-(5-((3-acrylamido-4-(morpholine-4-carbonyl)phenyl)amino)-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-methylphenyl)-4-(tert-butyl)benzamide (CHMFL-BTK-01) as a highly selective irreversible Bruton's tyrosine kinase (BTK) inhibitor.
Eur J Med Chem, 131, 2017
4GE6
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Crystal structure of human protein tyrosine phosphatase PTPN9 (MEG2) complex with compound 7
Descriptor: N-(4-bromo-3-methylbenzoyl)-4-[difluoro(phosphono)methyl]-L-phenylalanyl-N~5~-(3-iodobenzoyl)-L-ornithyl-3-{[(4-hydroxy-3-methoxyphenyl)acetyl]amino}-D-alaninamide, Tyrosine-protein phosphatase non-receptor type 9
Authors:Zhang, Z.-Y, Liu, S, Zhang, S.
Deposit date:2012-08-01
Release date:2012-10-31
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A Highly Selective and Potent PTP-MEG2 Inhibitor with Therapeutic Potential for Type 2 Diabetes.
J.Am.Chem.Soc., 134, 2012
3OLR
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PTPN22 in complex with consensus phospho-tyrosine peptide 1
Descriptor: SKAP2, Tyrosine-protein phosphatase non-receptor type 22
Authors:Yu, X, Sun, J.-P, Zhang, S, Zhang, Z.-Y.
Deposit date:2010-08-26
Release date:2011-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure basis of LYP substrate specificity revealed by reverse alanine screening and crystallography
To be Published
1VTI
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BU of 1vti by Molmil
DNA-DRUG INTERACTIONS: THE CRYSTAL STRUCTURES OF D(TGATCA) COMPLEXED WITH DAUNOMYCIN
Descriptor: DAUNOMYCIN, DNA (5'-D(*TP*GP*TP*AP*CP*A)-3')
Authors:Nunn, C.M, Van Meervelt, L, Zhang, S, Moore, M.H, Kennard, O.
Deposit date:1992-03-01
Release date:2011-07-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:DNA-Drug Interactions: The Crystal Structures of d(TGTACA) and d(TGATCA) Complexed with Daunomycin
J.Mol.Biol., 222, 1991
1VTH
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DNA-DRUG INTERACTIONS: THE CRYSTAL STRUCTURES OF D(TGTACA) COMPLEXED WITH DAUNOMYCIN
Descriptor: DAUNOMYCIN, DNA (5'-D(*TP*GP*TP*AP*CP*A)-3')
Authors:Nunn, C.M, Van Meervelt, L, Zhang, S, Moore, M.H, Kennard, O.
Deposit date:1992-03-01
Release date:2011-07-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:DNA-Drug Interactions: The Crystal Structures of d(TGTACA) and d(TGATCA) Complexed with Daunomycin
J.Mol.Biol., 222, 1991
1SMF
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Studies on an artificial trypsin inhibitor peptide derived from the mung bean inhibitor
Descriptor: BOWMAN-BIRK TYPE TRYPSIN INHIBITOR, CALCIUM ION, TRYPSIN
Authors:Huang, Q, Li, Y, Zhang, S, Liu, S, Tang, Y, Qi, C.
Deposit date:1992-10-24
Release date:1994-07-31
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Studies on an artificial trypsin inhibitor peptide derived from the mung bean trypsin inhibitor: chemical synthesis, refolding, and crystallographic analysis of its complex with trypsin.
J.Biochem.(Tokyo), 116, 1994
4HX1
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Structure of HLA-A68 complexed with a tumor antigen derived peptide
Descriptor: 9-mer peptide from Tyrosinase-related protein-2, Beta-2-microglobulin, GLYCEROL, ...
Authors:Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F.
Deposit date:2012-11-09
Release date:2013-10-02
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes
Mol.Immunol., 55, 2013
4HWZ
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Structure of HLA-A68 complexed with an HIV derived peptide
Descriptor: 9-mer peptide from Pol protein, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F.
Deposit date:2012-11-09
Release date:2013-10-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.397 Å)
Cite:Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes
Mol.Immunol., 55, 2013
8ILB
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BU of 8ilb by Molmil
The complexes of RbcL, AtRaf1 and AtBSD2 (LFB)
Descriptor: Protein BUNDLE SHEATH DEFECTIVE 2, chloroplastic, Ribulose bisphosphate carboxylase large chain, ...
Authors:Wang, R, Song, H, Zhang, W, Wang, N, Zhang, S, Shao, R.
Deposit date:2023-03-03
Release date:2023-11-01
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural insights into the functions of Raf1 and Bsd2 in hexadecameric Rubisco assembly.
Mol Plant, 16, 2023
8ILM
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BU of 8ilm by Molmil
The cryo-EM structure of eight Rubisco large subunits (RbcL), two Arabidopsis thaliana Rubisco accumulation factors 1 (AtRaf1), and seven Arabidopsis thaliana Bundle Sheath Defective 2 (AtBSD2)
Descriptor: Protein BUNDLE SHEATH DEFECTIVE 2, chloroplastic, Ribulose bisphosphate carboxylase large chain, ...
Authors:Wang, R, Song, H, Zhang, W, Wang, N, Zhang, S, Shao, R.
Deposit date:2023-03-03
Release date:2023-11-01
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insights into the functions of Raf1 and Bsd2 in hexadecameric Rubisco assembly.
Mol Plant, 16, 2023
8IO2
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The Rubisco assembly intermidate of Arabidopsis thaliana Rubisco accumulation factor 1 (AtRaf1) and Rubisco large subunit (RbcL)
Descriptor: Ribulose bisphosphate carboxylase large chain, Rubisco accumulation factor 1.2, chloroplastic
Authors:Wang, R, Song, H, Zhang, W, Wang, N, Zhang, S, Shao, R.
Deposit date:2023-03-10
Release date:2023-11-01
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insights into the functions of Raf1 and Bsd2 in hexadecameric Rubisco assembly.
Mol Plant, 16, 2023
8IOJ
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BU of 8ioj by Molmil
The Rubisco assembly intermidiate of Rubisco large subunit (RbcL) and Arabidopsis thaliana Rubisco accumulation factor 1 (AtRaf1)
Descriptor: Ribulose bisphosphate carboxylase large chain, Rubisco accumulation factor 1.2, chloroplastic
Authors:Wang, R, Song, H, Zhang, W, Wang, N, Zhang, S, Shao, R.
Deposit date:2023-03-11
Release date:2023-11-01
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural insights into the functions of Raf1 and Bsd2 in hexadecameric Rubisco assembly.
Mol Plant, 16, 2023
8IOL
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BU of 8iol by Molmil
The complex of Rubisco large subunit (RbcL)
Descriptor: Ribulose bisphosphate carboxylase large chain
Authors:Wang, R, Song, H, Zhang, W, Wang, N, Zhang, S, Shao, R.
Deposit date:2023-03-11
Release date:2023-11-01
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural insights into the functions of Raf1 and Bsd2 in hexadecameric Rubisco assembly.
Mol Plant, 16, 2023
1OZO
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BU of 1ozo by Molmil
Three-dimensional solution structure of apo-S100P protein determined by NMR spectroscopy
Descriptor: S-100P protein
Authors:Lee, Y.-C, Volk, D.E, Thiviyanathan, V, Kleerekoper, Q, Gribenko, A.V, Zhang, S, Gorenstein, D.G, Makhatadze, G.I, Luxon, B.A.
Deposit date:2003-04-09
Release date:2004-04-20
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR structure of the Apo-S100P protein.
J.Biomol.Nmr, 29, 2004
1OFX
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BU of 1ofx by Molmil
CRYSTAL STRUCTURE OF AN OKAZAKI FRAGMENT AT 2 ANGSTROMS RESOLUTION
Descriptor: DNA (5'-D(*GP*GP*GP*TP*AP*TP*AP*CP*GP*C)-3'), DNA/RNA (5'-R(*GP*CP*GP*)-D(*TP*AP*TP*AP*CP*CP*C)-3'), SPERMINE
Authors:Egli, M, Usman, N, Zhang, S, Rich, A.
Deposit date:1991-10-17
Release date:1993-04-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of an Okazaki fragment at 2-A resolution.
Proc.Natl.Acad.Sci.USA, 89, 1992
4DFI
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BU of 4dfi by Molmil
Crystal structure of cell adhesion molecule nectin-2/CD112 mutant FAMP
Descriptor: Poliovirus receptor-related protein 2
Authors:Liu, J, Qian, X, Chen, Z, Xu, X, Gao, F, Zhang, S, Zhang, R, Qi, J, Gao, G.F, Yan, J.
Deposit date:2012-01-23
Release date:2012-06-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Cell Adhesion Molecule Nectin-2/CD112 and Its Binding to Immune Receptor DNAM-1/CD226
J.Immunol., 188, 2012
4DFH
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Crystal structure of cell adhesion molecule nectin-2/CD112 variable domain
Descriptor: Poliovirus receptor-related protein 2
Authors:Liu, J, Qian, X, Chen, Z, Xu, X, Gao, F, Zhang, S, Zhang, R, Qi, J, Gao, G.F, Yan, J.
Deposit date:2012-01-23
Release date:2012-06-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of Cell Adhesion Molecule Nectin-2/CD112 and Its Binding to Immune Receptor DNAM-1/CD226
J.Immunol., 188, 2012
5JMC
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BU of 5jmc by Molmil
Receptor binding domain of Botulinum neurotoxin A in complex with rat SV2C
Descriptor: Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2C
Authors:Yao, G, Zhang, S, Mahrhold, S, Lam, K, Stern, D, Bagramyan, K, Perry, K, Kalkum, M, Rummel, A, Dong, M, Jin, R.
Deposit date:2016-04-28
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
Nat.Struct.Mol.Biol., 23, 2016
5JLV
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Receptor binding domain of Botulinum neurotoxin A in complex with human glycosylated SV2C
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
Authors:Yao, G, Zhang, S, Mahrhold, S, Lam, K, Stern, D, Bagramyan, K, Perry, K, Kalkum, M, Rummel, A, Dong, M, Jin, R.
Deposit date:2016-04-27
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
Nat.Struct.Mol.Biol., 23, 2016
3CO3
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BU of 3co3 by Molmil
X-Ray Crystal Structure of a Monofunctional Platinum-DNA Adduct, cis-{Pt(NH3)2(pyridine)}2+ Bound to Deoxyguanosine in a Dodecamer Duplex
Descriptor: 5'-D(*DCP*DCP*DTP*DCP*DTP*DCP*DGP*DTP*DCP*DTP*DCP*DC)-3', 5'-D(*DGP*DGP*DAP*DGP*DAP*DCP*DGP*DAP*DGP*DAP*DGP*DG)-3', cis-diammine(pyridine)chloroplatinum(II)
Authors:Lovejoy, K.S, Todd, R.C, Zhang, S, McCormick, M.S, D'Aquino, J.A, Reardon, J.T, Sancar, A, Giacomini, K.M, Lippard, S.J.
Deposit date:2008-03-27
Release date:2008-06-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:cis-Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3L4A
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BU of 3l4a by Molmil
Crystal Structure of an Anopheles gambiae Odorant-binding Protein 22a
Descriptor: AMMONIUM ION, GLYCEROL, Odorant binding protein (AGAP010409-PA)
Authors:Ren, H, Zhang, S.
Deposit date:2009-12-18
Release date:2011-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The Crystal Structure of an Anopheles gambiae Odorant-binding Protein AgamOBP22a and complexes with Bound Odorants
To be Published
3L47
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Crystal Structure of the Anopheles gambiae Odorant-binding Protein 22a
Descriptor: GOLD ION, Odorant binding protein (AGAP010409-PA)
Authors:Ren, H, Zhang, S.
Deposit date:2009-12-18
Release date:2011-01-12
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.506 Å)
Cite:The Crystal Structures of an Anopheles gambiae Odorant-binding Protein AgamOBP22a and complexes with bound Odorants
To be Published
3L4L
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Crystal Structure of an Anopheles gambiae Odorant-binding Protein AgamOBP22a with Bound Odorant Benzaldehyde
Descriptor: AMMONIUM ION, Odorant binding protein (AGAP010409-PA), benzaldehyde
Authors:Ren, H, Zhang, S.
Deposit date:2009-12-20
Release date:2011-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structures of an Anopheles gambiae Odorant-binding Protein Agam22a and Complexes with Bound Odorants
To be Published

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