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PDB: 342 件

2L3E
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Solution structure of P2a-J2a/b-P2b of human telomerase RNA
分子名称: 35-MER
著者Zhang, Q, Kim, N, Peterson, R.D, Wang, Z, Feigon, J.
登録日2010-09-13
公開日2010-11-17
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Inaugural Article: Structurally conserved five nucleotide bulge determines the overall topology of the core domain of human telomerase RNA.
Proc.Natl.Acad.Sci.USA, 107, 2010
3V3Q
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Crystal Structure of Human Nur77 Ligand-binding Domain in Complex with Ethyl 2-[2,3,4 trimethoxy-6(1-octanoyl)phenyl]acetate
分子名称: GLYCEROL, Nuclear receptor subfamily 4 group A member 1, SODIUM ION, ...
著者Zhang, Q, Shi, C, Yang, K, Chen, Y, Zhan, Y, Wu, Q, Lin, T.
登録日2011-12-14
公開日2012-09-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK
Nat.Chem.Biol., 8, 2012
3V3E
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Crystal Structure of the Human Nur77 Ligand-binding Domain
分子名称: GLYCEROL, Nuclear receptor subfamily 4 group A member 1
著者Zhang, Q, Shi, C, Yang, K, Chen, Y, Zhan, Y, Wu, Q, Lin, T.
登録日2011-12-13
公開日2012-09-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK
Nat.Chem.Biol., 8, 2012
6LI6
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Crystal structure of MCR-1-S treated by Au(PEt3)Cl
分子名称: GOLD ION, Probable phosphatidylethanolamine transferase Mcr-1, TRIETHYLPHOSPHANE
著者Zhang, Q, Wang, M, Sun, H.
登録日2019-12-10
公開日2020-09-16
最終更新日2020-10-28
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Resensitizing carbapenem- and colistin-resistant bacteria to antibiotics using auranofin.
Nat Commun, 11, 2020
4JGV
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Crystal Structure of Human Nur77 Ligand-binding Domain in Complex with THPN
分子名称: 1-(3,4,5-trihydroxyphenyl)nonan-1-one, GLYCEROL, Nuclear receptor subfamily 4 group A member 1
著者Zhang, Q, Li, F, Li, A, Tian, X, Wan, W, Wan, Y, Chen, H, Xing, Y, Wu, Q, Lin, T.
登録日2013-03-04
公開日2013-12-18
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway.
Nat.Chem.Biol., 10, 2014
2VH4
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Structure of a loop C-sheet serpin polymer
分子名称: TENGPIN
著者Zhang, Q, Law, R.H.P, Bottomley, S.P, Whisstock, J.C, Buckle, A.M.
登録日2007-11-19
公開日2008-01-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献A Structural Basis for Loop C-Sheet Polymerization in Serpins.
J.Mol.Biol., 376, 2008
3J32
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An asymmetric unit map from electron cryo-microscopy of Haliotis diversicolor molluscan hemocyanin isoform 1 (HdH1)
分子名称: Hemocyanin isoform 1
著者Zhang, Q, Dai, X, Cong, Y, Zhang, J, Chen, D.-H, Dougherty, M, Wang, J, Ludtke, S, Schmid, M.F, Chiu, W.
登録日2013-02-20
公開日2013-04-17
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Cryo-EM structure of a molluscan hemocyanin suggests its allosteric mechanism.
Structure, 21, 2013
1PQQ
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NMR Structure of a Cyclic Polyamide-DNA Complex
分子名称: 45-(3-AMINOPROPYL)-5,11,22,28,34-PENTAMETHYL-3,9,15,20,26,32,38,43-OCTAOXO-2,5,8,14,19,22,25,28,31,34,37,42,45,48-TETRADECAAZA-11-AZONIAHEPTACYCLO[42.2.1.1~4,7~.1~10,13~.1~21,24~.1~27,30~.1~33,36~]DOPENTACONTA-1(46),4(52),6,10(51),12,21(50),23,27(49),29,33(48),35,44(47)-DODECAENE, 5'-D(*CP*GP*CP*TP*AP*AP*CP*AP*GP*GP*C)-3', 5'-D(*GP*CP*CP*TP*GP*TP*TP*AP*GP*CP*G)-3'
著者Zhang, Q, Dwyer, T.J, Tsui, V, Case, D.A, Cho, J, Dervan, P.B, Wemmer, D.E.
登録日2003-06-18
公開日2004-06-29
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR Structure of a Cyclic Polyamide-DNA Complex.
J.Am.Chem.Soc., 126, 2004
1I9F
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STRUCTURAL CHARACTERIZATION OF THE COMPLEX OF THE REV RESPONSE ELEMENT RNA WITH A SELECTED PEPTIDE
分子名称: REV RESPONSE ELEMENT RNA, RSG-1.2 PEPTIDE
著者Zhang, Q, Harada, K, Cho, H.S, Frankel, A, Wemmer, D.E.
登録日2001-03-19
公開日2001-05-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural characterization of the complex of the Rev response element RNA with a selected peptide.
Chem.Biol., 8, 2001
5YJZ
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The native crystal structure of Rv3197 from Mycobacterium tuberculosis
分子名称: GLYCEROL, Probable conserved ATP-binding protein ABC transporter, SULFATE ION
著者Zhang, Q.Q, Rao, Z.H.
登録日2017-10-11
公開日2018-02-07
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Discovery of the first macrolide antibiotic binding protein in Mycobacterium tuberculosis: a new antibiotic resistance drug target.
Protein Cell, 9, 2018
8GOF
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Structure of hSLC19A1+PMX
分子名称: 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID, Reduced folate transporter
著者Zhang, Q.X, Zhang, X.Y, Zhu, Y.L, Sun, P.P, Gao, A, Zhang, L.G, Gao, P.
登録日2022-08-24
公開日2022-10-05
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Recognition of cyclic dinucleotides and folates by human SLC19A1.
Nature, 612, 2022
8GOE
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Structure of hSLC19A1+5-MTHF
分子名称: N-[4-({[(6S)-2-AMINO-4-HYDROXY-5-METHYL-5,6,7,8-TETRAHYDROPTERIDIN-6-YL]METHYL}AMINO)BENZOYL]-L-GLUTAMIC ACID, Reduced folate transporter
著者Zhang, Q.X, Zhang, X.Y, Zhu, Y.L, Sun, P.P, Gao, A, Zhang, L.G, Gao, P.
登録日2022-08-24
公開日2022-10-05
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Recognition of cyclic dinucleotides and folates by human SLC19A1.
Nature, 612, 2022
4FWE
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Native structure of LSD2 /AOF1/KDM1b in spacegroup of C2221 at 2.13A
分子名称: CITRATE ANION, FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1B, ...
著者Zhang, Q, Chen, Z.
登録日2012-07-01
公開日2013-01-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b
Cell Res., 23, 2013
4FWF
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Complex structure of LSD2/AOF1/KDM1b with H3K4 mimic
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Histone H3.1, Lysine-specific histone demethylase 1B, ...
著者Zhang, Q, Chen, Z.
登録日2012-07-01
公開日2013-01-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b
Cell Res., 23, 2013
4FWJ
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Native structure of LSD2/AOF1/KDM1b in spacegroup of I222 at 2.9A
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1B, PHOSPHATE ION, ...
著者Zhang, Q, Chen, Z.
登録日2012-07-01
公開日2013-01-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b
Cell Res., 23, 2013
9AYY
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BU of 9ayy by Molmil
SARS-CoV-2 Omicron-EG.5.1 3-RBD down Spike Protein Trimer 3 (S-GSAS-Omicron-EG.5.1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Zhang, Q.E, Acharya, P.
登録日2024-03-08
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献SARS-CoV-2 Omicron-EG.5.1 3-RBD down Spike Protein Trimer 3 (S-GSAS-Omicron-EG.5.1)
To Be Published
9AYW
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SARS-CoV-2 Omicron-EG.5.1 3-RBD down Spike Protein Trimer 1 (S-GSAS-Omicron-EG.5.1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Zhang, Q.E, Acharya, P.
登録日2024-03-08
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献SARS-CoV-2 Omicron-EG.5.1 3-RBD down Spike Protein Trimer 1 (S-GSAS-Omicron-EG.5.1)
To Be Published
9AYX
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SARS-CoV-2 Omicron-EG.5.1 3-RBD down Spike Protein Trimer 2 (S-GSAS-Omicron-EG.5.1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Zhang, Q.E, Acharya, P.
登録日2024-03-08
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献SARS-CoV-2 Omicron-EG.5.1 3-RBD down Spike Protein Trimer 2 (S-GSAS-Omicron-EG.5.1)
To Be Published
2DO8
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BU of 2do8 by Molmil
Solution Structure of UPF0301 protein HD_1794
分子名称: UPF0301 protein HD_1794
著者Zhang, Q, Liu, G, Shastry, R, Jiang, M, Cunningham, K, Ma, L.C, Xiao, R, Acton, T.R, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
登録日2006-04-27
公開日2006-05-25
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution Structure of UPF0301 protein HD_1794
To be published
2PEE
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BU of 2pee by Molmil
Crystal Structure of a Thermophilic Serpin, Tengpin, in the Native State
分子名称: GLYCEROL, SULFATE ION, Serine protease inhibitor
著者Zhang, Q.W, Buckle, A.M, Whisstock, J.C.
登録日2007-04-02
公開日2007-06-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The N terminus of the serpin, tengpin, functions to trap the metastable native state.
Embo Rep., 8, 2007
2PEF
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Crystal Structure of a Thermophilic Serpin, Tengpin, in the Latent State
分子名称: Serine protease inhibitor
著者Zhang, Q.W, Buckle, A.M, Whisstock, J.C.
登録日2007-04-03
公開日2007-06-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The N terminus of the serpin, tengpin, functions to trap the metastable native state.
Embo Rep., 8, 2007
5KH8
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BU of 5kh8 by Molmil
Solution structures of the apo state fluoride riboswitch
分子名称: riboswitch (47-MER)
著者Zhang, Q, Zhao, B.
登録日2016-06-14
公開日2017-07-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献An excited state underlies gene regulation of a transcriptional riboswitch.
Nat. Chem. Biol., 13, 2017
6V3X
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Crystal structure of EED in complex with PALI1-K1241me3 peptide
分子名称: PALI1 peptide, Polycomb protein EED
著者Zhang, Q, Davidovich, C.
登録日2019-11-26
公開日2021-05-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献PALI1 facilitates DNA and nucleosome binding by PRC2 and triggers an allosteric activation of catalysis.
Nat Commun, 12, 2021
6V3Y
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Crystal structure of EED in complex with PALI1-K1219me3 peptide
分子名称: PALI1 peptide, Polycomb protein EED
著者Zhang, Q, Davidovich, C.
登録日2019-11-26
公開日2021-05-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献PALI1 facilitates DNA and nucleosome binding by PRC2 and triggers an allosteric activation of catalysis.
Nat Commun, 12, 2021
6LJA
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Crystal Structure of exoHep from Bacteroides intestinalis DSM 17393 complexed with disaccharide product
分子名称: 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, CALCIUM ION, Heparinase II/III-like protein
著者Zhang, Q.D, Cao, H.Y, Wei, L, Li, F.C, Zhang, Y.Z.
登録日2019-12-13
公開日2020-12-23
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.978 Å)
主引用文献Discovery of exolytic heparinases and their catalytic mechanism and potential application.
Nat Commun, 12, 2021

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件を2024-08-21に公開中

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