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PDB: 422 件

8OO7
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CryoEM Structure INO80core Hexasome complex composite model state1
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 5, ...
著者Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S.
登録日2023-04-04
公開日2023-07-26
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling.
Science, 381, 2023
7L0R
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Structure of NTS-NTSR1-Gi complex in lipid nanodisc, noncanonical state, without AHD
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Zhang, M, Gui, M, Wang, Z, Gorgulla, C, Yu, J.J, Wu, H, Sun, Z, Klenk, C, Merklinger, L, Morstein, L, Hagn, F, Pluckthun, A, Brown, A, Nasr, M.L, Wagner, G.
登録日2020-12-12
公開日2021-01-06
最終更新日2021-03-24
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs.
Nat.Struct.Mol.Biol., 28, 2021
7L0P
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Structure of NTS-NTSR1-Gi complex in lipid nanodisc, canonical state, without AHD
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Zhang, M, Gui, M, Wang, Z, Gorgulla, C, Yu, J.J, Wu, H, Sun, Z, Klenk, C, Merklinger, L, Morstein, L, Hagn, F, Pluckthun, A, Brown, A, Nasr, M.L, Wagner, G.
登録日2020-12-12
公開日2021-01-06
最終更新日2021-03-24
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs.
Nat.Struct.Mol.Biol., 28, 2021
7L0S
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Structure of NTS-NTSR1-Gi complex in lipid nanodisc, noncanonical state, with AHD
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Zhang, M, Gui, M, Wang, Z, Gorgulla, C, Yu, J.J, Wu, H, Sun, Z, Klenk, C, Merklinger, L, Morstein, L, Hagn, F, Pluckthun, A, Brown, A, Nasr, M.L, Wagner, G.
登録日2020-12-12
公開日2021-01-06
最終更新日2021-03-24
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs.
Nat.Struct.Mol.Biol., 28, 2021
7LH9
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Crystal structure of BRPF2 PWWP domain in complex with DNA
分子名称: Bromodomain-containing protein 1, DNA
著者Zhang, M, Lei, M, Qin, S, Dong, A, Yang, A, Li, Y, Loppnau, P, Hughes, T.R, Arrowsmith, C.H, Edwards, A.M, Min, J, Liu, J, Structural Genomics Consortium (SGC)
登録日2021-01-21
公開日2021-02-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the BRPF2 PWWP domain in complex with DNA reveals a different binding mode than the HDGF family of PWWP domains.
Biochim Biophys Acta Gene Regul Mech, 1864, 2021
5TO2
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Crystal structure of streptavidin with one wild type subunit and three mutated subunits (N23A/S27D/S45A)
分子名称: DI(HYDROXYETHYL)ETHER, Streptavidin
著者Zhang, M, Biswas, S, Deng, W, Yu, H.
登録日2016-10-16
公開日2017-05-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of streptavidin with one wild type subunit and three mutated subunits (N23A/S27D/S45A)
To Be Published
7CSP
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Structure of Ephexin4 IDPSH
分子名称: Rho guanine nucleotide exchange factor 16
著者Zhang, M, Lin, L, Wang, C, Zhu, J.
登録日2020-08-15
公開日2021-02-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Double inhibition and activation mechanisms of Ephexin family RhoGEFs.
Proc.Natl.Acad.Sci.USA, 118, 2021
7CSR
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Structure of Ephexin4 R676L
分子名称: Rho guanine nucleotide exchange factor 16
著者Zhang, M, Lin, L, Wang, C, Zhu, J.
登録日2020-08-17
公開日2021-02-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Double inhibition and activation mechanisms of Ephexin family RhoGEFs.
Proc.Natl.Acad.Sci.USA, 118, 2021
7CSO
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Structure of Ephexin4 DH-PH-SH3
分子名称: Rho guanine nucleotide exchange factor 16, SULFATE ION
著者Zhang, M, Lin, L, Wang, C, Zhu, J.
登録日2020-08-15
公開日2021-02-24
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Double inhibition and activation mechanisms of Ephexin family RhoGEFs.
Proc.Natl.Acad.Sci.USA, 118, 2021
7L0Q
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Structure of NTS-NTSR1-Gi complex in lipid nanodisc, canonical state, with AHD
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Zhang, M, Gui, M, Wang, Z, Gorgulla, C, Yu, J.J, Wu, H, Sun, Z, Klenk, C, Merklinger, L, Morstein, L, Hagn, F, Pluckthun, A, Brown, A, Nasr, M.L, Wagner, G.
登録日2020-12-12
公開日2021-01-06
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs.
Nat.Struct.Mol.Biol., 28, 2021
3S05
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BU of 3s05 by Molmil
mEos2 Fluorescent Protein-Green Form
分子名称: Green to red photoconvertible GPF-like protein EosFP
著者Zhang, M.S, Wu, L.J, Xu, P.Y, Liu, Y.F, Xu, T.
登録日2011-05-13
公開日2011-11-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.204 Å)
主引用文献mEos2 Fluorescent Protein-Green Form
To be Published
3SJQ
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Crystal structure of a small conductance potassium channel splice variant complexed with calcium-calmodulin
分子名称: 1-phenylurea, CALCIUM ION, Calmodulin, ...
著者Zhang, M, Pascal, J.M, Zhang, J.-F.
登録日2011-06-21
公開日2012-05-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for calmodulin as a dynamic calcium sensor.
Structure, 20, 2012
3TDB
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Human Pin1 bound to trans peptidomimetic inhibitor
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, N-[(1E,2R)-1-[(2R)-2-{[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl}cyclopentylidene]-3-(phosphonooxy)propan-2-yl]-L-phenylalaninamide, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Zhang, M, Zhang, Y.
登録日2011-08-10
公開日2012-06-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.267 Å)
主引用文献Structural and Kinetic Analysis of Prolyl-isomerization/Phosphorylation Cross-Talk in the CTD Code.
Acs Chem.Biol., 7, 2012
3TCZ
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Human Pin1 bound to cis peptidomimetic inhibitor
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, N~2~-({(1R,2Z)-2-[(2R)-2-(formylamino)-3-(phosphonooxy)propylidene]cyclopentyl}carbonyl)-L-argininamide, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Zhang, M, Zhang, Y.
登録日2011-08-09
公開日2012-06-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and Kinetic Analysis of Prolyl-isomerization/Phosphorylation Cross-Talk in the CTD Code.
Acs Chem.Biol., 7, 2012
2JKI
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BU of 2jki by Molmil
Complex of Hsp90 N-terminal and Sgt1 CS domain
分子名称: ADENOSINE-5'-DIPHOSPHATE, CYTOSOLIC HEAT SHOCK PROTEIN 90, SGT1-LIKE PROTEIN
著者Zhang, M, Pearl, L.H.
登録日2008-08-28
公開日2008-10-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural and Functional Coupling of Hsp90- and Sgt1-Centred Multi-Protein Complexes.
Embo J., 27, 2008
2LA8
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BU of 2la8 by Molmil
Solution structure of INAD PDZ5 complexed with Kon-tiki peptide
分子名称: Inactivation-no-after-potential D protein,kon-tiki peptide
著者Zhang, M, Wen, W.
登録日2011-03-08
公開日2011-11-30
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The INAD scaffold is a dynamic, redox-regulated modulator of signaling in the Drosophila eye
Cell(Cambridge,Mass.), 145, 2011
2KBQ
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Solution structure of harmonin N terminal domain
分子名称: Harmonin
著者Zhang, M, Pan, L, Yan, J, Wu, L.
登録日2008-12-05
公開日2009-03-31
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Assembling stable hair cell tip link complex via multidentate interactions between harmonin and cadherin 23
Proc.Natl.Acad.Sci.USA, 106, 2009
4KGB
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BU of 4kgb by Molmil
Structure of succinyl-CoA: 3-ketoacid CoA transferase from Drosophila melanogaster
分子名称: SULFATE ION, Succinyl-CoA:3-ketoacid-coenzyme A transferase
著者Wang, Y.C, Shi, Z.B, Zhang, M.
登録日2013-04-29
公開日2013-10-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Structure of succinyl-CoA:3-ketoacid CoA transferase from Drosophila melanogaster.
Acta Crystallogr.,Sect.F, 69, 2013
1IU0
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BU of 1iu0 by Molmil
The first PDZ domain of PSD-95
分子名称: PSD-95
著者Long, J.-F, Tochio, H, Wang, P, Sala, C, Niethammer, M, Sheng, M, Zhang, M.
登録日2002-02-18
公開日2003-03-11
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Supramodular structure and synergistic target binding of the N-terminal tandem PDZ domains of PSD-95
J.MOL.BIOL., 327, 2003
6JJP
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Crystal structure of Fab of a PD-1 monoclonal antibody MW11-h317 in complex with PD-1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of MW11-h317, Programmed cell death protein 1, ...
著者Wang, M, Wang, J, Wang, R, Jiao, S, Wang, S, Zhang, J, Zhang, M.
登録日2019-02-26
公開日2019-10-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Identification of a monoclonal antibody that targets PD-1 in a manner requiring PD-1 Asn58 glycosylation.
Commun Biol, 2, 2019
6JMU
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Crystal structure of GIT1/Paxillin complex
分子名称: ARF GTPase-activating protein GIT1, Paxillin
著者Zhu, J, Lin, L, Xia, Y, Zhang, R, Zhang, M.
登録日2019-03-13
公開日2020-05-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献GIT/PIX Condensates Are Modular and Ideal for Distinct Compartmentalized Cell Signaling.
Mol.Cell, 79, 2020
4KP3
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Crystal Structure of MyoVa-GTD in Complex with Two Cargos
分子名称: Melanophilin, RILP-like protein 2, Unconventional myosin-Va
著者Wei, Z, Liu, X, Yu, C, Zhang, M.
登録日2013-05-13
公開日2013-07-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.405 Å)
主引用文献Structural basis of cargo recognitions for class V myosins
Proc.Natl.Acad.Sci.USA, 110, 2013
4WSI
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BU of 4wsi by Molmil
Crystal Structure of PALS1/Crb complex
分子名称: MAGUK p55 subfamily member 5, Protein crumbs
著者Wei, Z, Li, Y, Zhang, M.
登録日2014-10-28
公開日2014-11-26
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structure of Crumbs tail in complex with the PALS1 PDZ-SH3-GK tandem reveals a highly specific assembly mechanism for the apical Crumbs complex.
Proc.Natl.Acad.Sci.USA, 111, 2014
1SQP
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Crystal Structure Analysis of Bovine Bc1 with Myxothiazol
分子名称: (2Z,6E)-7-{2'-[(2E,4E)-1,6-DIMETHYLHEPTA-2,4-DIENYL]-2,4'-BI-1,3-THIAZOL-4-YL}-3,5-DIMETHOXY-4-METHYLHEPTA-2,6-DIENAMID E, (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ...
著者Esser, L, Quinn, B, Li, Y.F, Zhang, M, Elberry, M, Yu, L, Yu, C.A, Xia, D.
登録日2004-03-19
公開日2005-11-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystallographic studies of quinol oxidation site inhibitors: a modified classification of inhibitors for the cytochrome bc(1) complex.
J.Mol.Biol., 341, 2004
1SQQ
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Crystal Structure Analysis of Bovine Bc1 with Methoxy Acrylate Stilbene (MOAS)
分子名称: Cytochrome b, Cytochrome c1, heme protein, ...
著者Esser, L, Quinn, B, Li, Y.F, Zhang, M, Elberry, M, Yu, L, Yu, C.A, Xia, D.
登録日2004-03-19
公開日2005-10-25
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystallographic studies of quinol oxidation site inhibitors: a modified classification of inhibitors for the cytochrome bc(1) complex.
J.Mol.Biol., 341, 2004

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