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PDB: 1134 件

7KI1
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Taspoglutide-bound Glucagon-Like Peptide-1 (GLP-1) Receptor in Complex with Gs Protein
分子名称: Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Zhang, X, Belousoff, M.J, Danev, R, Sexton, P.M, Wootten, D.
登録日2020-10-22
公開日2021-08-04
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Structure and dynamics of semaglutide- and taspoglutide-bound GLP-1R-Gs complexes.
Cell Rep, 36, 2021
2MX6
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Complex structure of Dvl PDZ domain with ligand
分子名称: (PHQ)WV peptide, Segment polarity protein dishevelled homolog DVL-1
著者Zhang, X, Zheng, J.J.
登録日2014-12-15
公開日2015-12-30
実験手法SOLUTION NMR
主引用文献Protein-ligand interaction decoded by NMR chemical shift analysis
To be Published
7DVG
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BU of 7dvg by Molmil
Crystal structure of rice immune receptor RGA5-HMA5 mutant.
分子名称: Disease resistance protein RGA5
著者Zhang, X, Liu, J.F.
登録日2021-01-13
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of rice immune receptor RGA5-HMA5.
To Be Published
7XGD
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BU of 7xgd by Molmil
Cryo-EM structure of Apo-IGF1R map 1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin-like growth factor 1 receptor
著者Zhang, X, Wu, C.
登録日2022-04-04
公開日2023-04-12
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM structure of Apo-IGF1R
To Be Published
8I02
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BU of 8i02 by Molmil
Cryo-EM structure of the SIN3S complex from S. pombe
分子名称: Chromatin modification-related protein eaf3, Cph1, Histone deacetylase clr6, ...
著者Wang, C, Guo, Z, Zhan, X.
登録日2023-01-10
公開日2023-05-03
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Two assembly modes for SIN3 histone deacetylase complexes.
Cell Discov, 9, 2023
8I03
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BU of 8i03 by Molmil
Cryo-EM structure of the SIN3L complex from S. pombe
分子名称: Chromatin modification-related protein png2, Histone deacetylase clr6, POTASSIUM ION, ...
著者Wang, C, Guo, Z, Zhan, X.
登録日2023-01-10
公開日2023-05-03
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Two assembly modes for SIN3 histone deacetylase complexes.
Cell Discov, 9, 2023
5IJD
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BU of 5ijd by Molmil
The crystal structure of mouse TLR4/MD-2/lipid A complex
分子名称: (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Wang, Y, Su, L, Morin, M.D, Jones, B.T, Whitby, L.R, Surakattula, M, Huang, H, Shi, H, Choi, J.H, Wang, K, Moresco, E.M, Berger, M, Zhan, X, Zhang, H, Boger, D.L, Beutler, B.
登録日2016-03-01
公開日2016-04-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
5IJC
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The crystal structure of mouse TLR4/MD-2/neoseptin-3 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte antigen 96, ...
著者Wang, Y, Su, L, Morin, M.D, Jones, B.T, Whitby, L.R, Surakattula, M, Huang, H, Shi, H, Choi, J.H, Wang, K, Moresco, E.M, Berger, M, Zhan, X, Zhang, H, Boger, D.L, Beutler, B.
登録日2016-03-01
公開日2016-04-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
5IJB
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BU of 5ijb by Molmil
The ligand-free structure of the mouse TLR4/MD-2 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte antigen 96, ...
著者Wang, Y, Su, L, Morin, M.D, Jones, B.T, Whitby, L.R, Surakattula, M, Huang, H, Shi, H, Choi, J.H, Wang, K, Moresco, E.M, Berger, M, Zhan, X, Zhang, H, Boger, D.L, Beutler, B.
登録日2016-03-01
公開日2016-04-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
7V26
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BU of 7v26 by Molmil
XG005-bound SARS-CoV-2 S
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, XG005 Heavy chain, ...
著者Zhan, W.Q, Zhang, X, Sun, L, Chen, Z.G.
登録日2021-08-07
公開日2021-10-20
最終更新日2022-07-06
実験手法ELECTRON MICROSCOPY (3.85 Å)
主引用文献An ultrapotent pan-beta-coronavirus lineage B ( beta-CoV-B) neutralizing antibody locks the receptor-binding domain in closed conformation by targeting its conserved epitope.
Protein Cell, 13, 2022
7FIK
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BU of 7fik by Molmil
The cryo-EM structure of the CR subunit from X. laevis NPC
分子名称: MGC154553 protein, MGC83295 protein, MGC83926 protein, ...
著者Shi, Y, Huang, G, Zhan, X.
登録日2021-07-31
公開日2022-11-09
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex.
Science, 376, 2022
8H6K
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BU of 8h6k by Molmil
Cryo-EM structure of human exon-defined spliceosome in the mature B state.
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
著者Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y.
登録日2022-10-18
公開日2024-05-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural insights into human exon-defined spliceosome prior to activation.
Cell Res., 34, 2024
8H6L
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BU of 8h6l by Molmil
Cryo-EM structure of human exon-defined spliceosome in the early B state.
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
著者Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y.
登録日2022-10-18
公開日2024-05-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural insights into human exon-defined spliceosome prior to activation.
Cell Res., 34, 2024
8H6J
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BU of 8h6j by Molmil
Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state.
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
著者Zhang, W, Zhan, X, Zhang, X, Lei, J, Yan, C, Shi, Y.
登録日2022-10-18
公開日2024-05-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Structural insights into human exon-defined spliceosome prior to activation.
Cell Res., 34, 2024
8H6E
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BU of 8h6e by Molmil
Cryo-EM structure of human exon-defined spliceosome in the late pre-B state.
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
著者Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y.
登録日2022-10-17
公開日2024-05-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insights into human exon-defined spliceosome prior to activation.
Cell Res., 34, 2024
7FIL
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BU of 7fil by Molmil
The cryo-EM structure of the NTD2 from the X. laevis Nup358
分子名称: Nup358 complex, clamps
著者Shi, Y, Zhan, X, Huang, G.
登録日2021-07-31
公開日2022-06-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex.
Science, 376, 2022
7C4J
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BU of 7c4j by Molmil
Cryo-EM structure of the yeast Swi/Snf complex in a nucleosome free state
分子名称: Actin-like protein ARP9, Actin-related protein 7, Regulator of Ty1 transposition protein 102, ...
著者Wang, C.C, Guo, Z.Y, Zhan, X.C, Zhang, X.F.
登録日2020-05-18
公開日2020-07-15
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.89 Å)
主引用文献Structure of the yeast Swi/Snf complex in a nucleosome free state
Nat Commun, 2020
3P2D
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BU of 3p2d by Molmil
Crystal structure of arrestin-3 reveals the basis of the difference in receptor binding between two non-visual subtypes
分子名称: Beta-arrestin-2
著者Spiller, B.W, Gurevich, V.V, Zhan, X, Gimenez, L.E.
登録日2010-10-01
公開日2011-01-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal Structure of Arrestin-3 Reveals the Basis of the Difference in Receptor Binding Between Two Non-visual Subtypes.
J.Mol.Biol., 406, 2011
8JHZ
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BU of 8jhz by Molmil
Cryo-EM structure of the TcsH-TMPRSS2 complex
分子名称: Hemorrhagic toxin, Transmembrane protease serine 2, ZINC ION
著者Zhou, R, Liang, T, Zhan, X.
登録日2023-05-25
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Molecular basis of TMPRSS2 recognition by Paeniclostridium sordellii hemorrhagic toxin.
Nat Commun, 15, 2024
8JI0
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Cryo-EM structure of the TcsH-CROP in complex with TMPRSS2
分子名称: Maltose/maltodextrin-binding periplasmic protein,Hemorrhagic toxin, Transmembrane protease serine 2
著者Zhou, R, Tao, L, Zhan, X.
登録日2023-05-25
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Molecular basis of TMPRSS2 recognition by Paeniclostridium sordellii hemorrhagic toxin.
Nat Commun, 15, 2024
7WHK
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BU of 7whk by Molmil
The state 3 complex structure of Omicron spike with Bn03 (2-up RBD, 5 nanobodies)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Bn03_nano1, Bn03_nano2, ...
著者Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L.
登録日2021-12-30
公開日2022-05-11
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody.
Cell, 185, 2022
7WHI
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The state 2 complex structure of Omicron spike with Bn03 (2-up RBD, 4 nanobodies)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Bn03_nano1, Bn03_nano2, ...
著者Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L.
登録日2021-12-30
公開日2022-05-11
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody.
Cell, 185, 2022
7WHJ
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The state 1 complex structure of Omicron spike with Bn03 (1-up RBD, 3 nanobodies)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Bn03_nano1, Bn03_nano2, ...
著者Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L.
登録日2021-12-30
公開日2022-05-11
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody.
Cell, 185, 2022
7WZ2
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BU of 7wz2 by Molmil
SARS-CoV-2 (D614G) Spike trimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L.
登録日2022-02-16
公開日2022-07-20
最終更新日2022-09-14
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural Study of SARS-CoV-2 Antibodies Identifies a Broad-Spectrum Antibody That Neutralizes the Omicron Variant by Disassembling the Spike Trimer.
J.Virol., 96, 2022
7WZ1
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SARS-CoV-2 Omicron Spike trimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L.
登録日2022-02-16
公開日2022-07-27
最終更新日2022-09-14
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural Study of SARS-CoV-2 Antibodies Identifies a Broad-Spectrum Antibody That Neutralizes the Omicron Variant by Disassembling the Spike Trimer.
J.Virol., 96, 2022

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件を2024-06-19に公開中

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