4WBB
 
 | | Single Turnover Autophosphorylation Cycle of the PKA RIIb Holoenzyme | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... | | 著者 | Zhang, P, Knape, M.J, Ahuja, L.G, Keshwani, M.M, King, C.C, Sastri, M, Herberg, F.W, Taylor, S.S. | | 登録日 | 2014-09-02 | | 公開日 | 2015-05-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Single Turnover Autophosphorylation Cycle of the PKA RII beta Holoenzyme.
Plos Biol., 13, 2015
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6W9E
 | | Crystal Structure of Human CDK9/cyclinT1 in complex with MC180295 | | 分子名称: | (4-amino-2-{[(1R,2R,4S)-bicyclo[2.2.1]heptan-2-yl]amino}-1,3-thiazol-5-yl)(2-nitrophenyl)methanone, (4-amino-2-{[(1S,2S,4R)-bicyclo[2.2.1]heptan-2-yl]amino}-1,3-thiazol-5-yl)(2-nitrophenyl)methanone, Cyclin-T1, ... | | 著者 | Zhang, P, Wu, J. | | 登録日 | 2020-03-22 | | 公開日 | 2021-09-01 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Comparative Modeling of CDK9 Inhibitors to Explore Selectivity and Structure-Activity Relationships
To Be Published
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3EPD
 | | CryoEM structure of poliovirus receptor bound to poliovirus type 3 | | 分子名称: | MYRISTIC ACID, Poliovirus Type3 peptide, Poliovirus receptor, ... | | 著者 | Zhang, P, Mueller, S, Morais, M.C, Bator, C.M, Bowman, V.D, Hafenstein, S, Wimmer, E, Rossmann, M.G. | | 登録日 | 2008-09-29 | | 公開日 | 2008-11-11 | | 最終更新日 | 2024-04-17 | | 実験手法 | ELECTRON MICROSCOPY (9 Å) | | 主引用文献 | Crystal structure of CD155 and electron microscopic studies of its complexes with polioviruses.
Proc.Natl.Acad.Sci.USA, 105, 2008
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3EPC
 | | CryoEM structure of poliovirus receptor bound to poliovirus type 1 | | 分子名称: | MYRISTIC ACID, Poliovirus receptor, Protein VP1, ... | | 著者 | Zhang, P, Mueller, S, Morais, M.C, Bator, C.M, Bowman, V.D, Hafenstein, S, Wimmer, E, Rossmann, M.G. | | 登録日 | 2008-09-29 | | 公開日 | 2008-11-11 | | 最終更新日 | 2024-04-17 | | 実験手法 | ELECTRON MICROSCOPY (8 Å) | | 主引用文献 | Crystal structure of CD155 and electron microscopic studies of its complexes with polioviruses.
Proc.Natl.Acad.Sci.USA, 105, 2008
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3EPF
 | | CryoEM structure of poliovirus receptor bound to poliovirus type 2 | | 分子名称: | 1[2-CHLORO-4-METHOXY-PHENYL-OXYMETHYL]-4-[2,6-DICHLORO-PHENYL-OXYMETHYL]-BENZENE, MYRISTIC ACID, Poliovirus receptor, ... | | 著者 | Zhang, P, Mueller, S, Morais, M.C, Bator, C.M, Bowman, V.D, Hafenstein, S, Wimmer, E, Rossmann, M.G. | | 登録日 | 2008-09-29 | | 公開日 | 2008-11-11 | | 最終更新日 | 2024-04-17 | | 実験手法 | ELECTRON MICROSCOPY (9 Å) | | 主引用文献 | Crystal structure of CD155 and electron microscopic studies of its complexes with polioviruses.
Proc.Natl.Acad.Sci.USA, 105, 2008
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3BLF
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3BLI
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3BLE
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4X6R
 | | An Isoform-specific Myristylation Switch Targets RIIb PKA Holoenzymes to Membranes | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Zhang, P, Ye, F, Bastidas, A.C, Kornev, A.P, Ginsberg, M.H, Wu, J, Taylor, S.S. | | 登録日 | 2014-12-09 | | 公開日 | 2015-07-22 | | 最終更新日 | 2020-06-24 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | An Isoform-Specific Myristylation Switch Targets Type II PKA Holoenzymes to Membranes.
Structure, 23, 2015
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4X6Q
 | | An Isoform-specific Myristylation Switch Targets RIIb PKA Holoenzymes to Membranes | | 分子名称: | cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type II-beta regulatory subunit | | 著者 | Zhang, P, Ye, F, Bastidas, A.C, Kornev, A.P, Ginsberg, M.H, Taylor, S.S. | | 登録日 | 2014-12-08 | | 公開日 | 2015-07-22 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | | 主引用文献 | An Isoform-Specific Myristylation Switch Targets Type II PKA Holoenzymes to Membranes.
Structure, 23, 2015
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4X8P
 | | Crystal structure of Ash2L SPRY domain in complex with RbBP5 | | 分子名称: | GLYCEROL, Retinoblastoma-binding protein 5, Set1/Ash2 histone methyltransferase complex subunit ASH2,Set1/Ash2 histone methyltransferase complex subunit ASH2 | | 著者 | Zhang, P, Chaturvedi, C.P, Brunzelle, J.S, Skiniotis, G, Brand, M, Shilatifard, A, Couture, J.-F. | | 登録日 | 2014-12-10 | | 公開日 | 2015-01-28 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A phosphorylation switch on RbBP5 regulates histone H3 Lys4 methylation.
Genes Dev., 29, 2015
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4X8N
 | | Crystal structure of Ash2L SPRY domain in complex with phosphorylated RbBP5 | | 分子名称: | Retinoblastoma-binding protein 5, Set1/Ash2 histone methyltransferase complex subunit ASH2 | | 著者 | Zhang, P, Chaturvedi, C.P, Brunzelle, J.S, Skiniotis, G, Brand, M, Shilatifard, A, Couture, J.-F. | | 登録日 | 2014-12-10 | | 公開日 | 2015-01-28 | | 最終更新日 | 2020-01-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A phosphorylation switch on RbBP5 regulates histone H3 Lys4 methylation.
Genes Dev., 29, 2015
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3F6G
 | | Crystal structure of the regulatory domain of LiCMS in complexed with isoleucine - type II | | 分子名称: | Alpha-isopropylmalate synthase, ISOLEUCINE, SULFATE ION, ... | | 著者 | Zhang, P, Ma, J, Zhao, G, Ding, J. | | 登録日 | 2008-11-06 | | 公開日 | 2009-04-21 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Molecular basis of the inhibitor selectivity and insights into the feedback inhibition mechanism of citramalate synthase from Leptospira interrogans
Biochem.J., 421, 2009
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3F6H
 | | Crystal structure of the regulatory domain of LiCMS in complexed with isoleucine - type III | | 分子名称: | Alpha-isopropylmalate synthase, ISOLEUCINE, ZINC ION | | 著者 | Zhang, P, Ma, J, Zhao, G, Ding, J. | | 登録日 | 2008-11-06 | | 公開日 | 2009-04-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Molecular basis of the inhibitor selectivity and insights into the feedback inhibition mechanism of citramalate synthase from Leptospira interrogans
Biochem.J., 421, 2009
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6DLO
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6DLP
 | | Crystal structure of LRRK2 WD40 domain dimer | | 分子名称: | Leucine-rich repeat serine/threonine-protein kinase 2, PLATINUM (II) ION | | 著者 | Zhang, P, Ru, H, Wang, L, Wu, H. | | 登録日 | 2018-06-02 | | 公開日 | 2019-01-09 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (4 Å) | | 主引用文献 | Crystal structure of the WD40 domain dimer of LRRK2.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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5HV2
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5HV1
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5HV6
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5HV3
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8JES
 | | Cryo-EM structure of DltB homo-tetramer | | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, DIACYL GLYCEROL, DODECYL-BETA-D-MALTOSIDE, ... | | 著者 | Zhang, P, Liu, Z. | | 登録日 | 2023-05-16 | | 公開日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | | 主引用文献 | Structural insights into the transporting and catalyzing mechanism of DltB in LTA D-alanylation.
Nat Commun, 15, 2024
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8JF2
 | | Cryo-EM structure of tetrameric DltB/DltC complex | | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, D-alanyl carrier protein, DIACYL GLYCEROL, ... | | 著者 | Zhang, P, Liu, Z. | | 登録日 | 2023-05-17 | | 公開日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural insights into the transporting and catalyzing mechanism of DltB in LTA D-alanylation.
Nat Commun, 15, 2024
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8JEM
 | | DltB tetramer in complex with inhibitor m-AMSA | | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, DIACYL GLYCEROL, DODECYL-BETA-D-MALTOSIDE, ... | | 著者 | Zhang, P, Liu, Z. | | 登録日 | 2023-05-16 | | 公開日 | 2024-05-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | | 主引用文献 | Structural insights into the transporting and catalyzing mechanism of DltB in LTA D-alanylation.
Nat Commun, 15, 2024
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7V1A
 | | Stapled TBS peptide from RIAM bound to talin R7R8 domains | | 分子名称: | 1,2-ETHANEDIOL, ASP-ILE-ASP-GLN-MET-PHE-SER-THR-LEU-LEU-GLY-GLU-MK8-ASP-LEU-LEU-MK8-GLN-SER, Talin-1 | | 著者 | Zhang, P, Gao, T, Wu, J. | | 登録日 | 2022-05-11 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.845 Å) | | 主引用文献 | Inhibition of talin-induced integrin activation by a double-hit stapled peptide.
Structure, 31, 2023
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1DRO
 | | NMR STRUCTURE OF THE CYTOSKELETON/SIGNAL TRANSDUCTION PROTEIN | | 分子名称: | BETA-SPECTRIN | | 著者 | Zhang, P, Talluri, S, Deng, H, Branton, D, Wagner, G. | | 登録日 | 1995-09-29 | | 公開日 | 1996-04-03 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the pleckstrin homology domain of Drosophila beta-spectrin.
Structure, 3, 1995
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