6MTP
 
 | | Crystal structure of VRC42.04 Fab in complex with gp41 peptide | | Descriptor: | Antibody VRC42.04 Fab heavy chain, Antibody VRC42.04 Fab light chain, RV217 founder virus gp41 peptide | | Authors: | Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Zhang, B, Doria-Rose, N.A, Kwong, P.D. | | Deposit date: | 2018-10-21 | | Release date: | 2019-03-27 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.036 Å) | | Cite: | Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Immunity, 50, 2019
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7CAF
 | | Mycobacterium smegmatis LpqY-SugABC complex in the pre-translocation state | | Descriptor: | ABC sugar transporter, permease component, ABC transporter, ... | | Authors: | Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T, Rao, Z. | | Deposit date: | 2020-06-08 | | Release date: | 2020-12-02 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC.
Sci Adv, 6, 2020
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7CAG
 | | Mycobacterium smegmatis LpqY-SugABC complex in the catalytic intermediate state | | Descriptor: | ABC sugar transporter, permease component, ABC transporter, ... | | Authors: | Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T. | | Deposit date: | 2020-06-08 | | Release date: | 2020-12-02 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.78 Å) | | Cite: | Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC.
Sci Adv, 6, 2020
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7CAD
 | | Mycobacterium smegmatis SugABC complex | | Descriptor: | ABC sugar transporter, permease component, ABC transporter, ... | | Authors: | Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T, Rao, Z. | | Deposit date: | 2020-06-08 | | Release date: | 2020-12-02 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.41 Å) | | Cite: | Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC.
Sci Adv, 6, 2020
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7CAE
 | | Mycobacterium smegmatis LpqY-SugABC complex in the resting state | | Descriptor: | ABC sugar transporter, permease component, ABC transporter, ... | | Authors: | Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T, Rao, Z. | | Deposit date: | 2020-06-08 | | Release date: | 2020-12-02 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.44 Å) | | Cite: | Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC.
Sci Adv, 6, 2020
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7DSF
 | | The Crystal Structure of human SPR from Biortus. | | Descriptor: | ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Sepiapterin reductase, ... | | Authors: | Wang, F, Lv, Z, Cheng, W, Lin, D, Meng, Q, Zhang, B, Huang, Y. | | Deposit date: | 2020-12-31 | | Release date: | 2021-01-13 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The Crystal Structure of human SPR from Biortus.
To Be Published
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7ESF
 | | The Crystal Structure of human MTH1 from Biortus | | Descriptor: | 7,8-dihydro-8-oxoguanine triphosphatase, DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL | | Authors: | Wang, F, Cheng, W, Shang, H, Wang, R, Zhang, B, Tian, F. | | Deposit date: | 2021-05-10 | | Release date: | 2021-05-26 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | The Crystal Structure of human MTH1 from Biortus
To Be Published
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7EPK
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7ZEA
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7ZCZ
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7ZHI
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7ZP2
 | | Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum in complex with BDA-04 | | Descriptor: | Aspartate carbamoyltransferase, SODIUM ION, SULFATE ION, ... | | Authors: | Wang, C, Zhang, B, Groves, M.R. | | Deposit date: | 2022-04-26 | | Release date: | 2022-08-24 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.292 Å) | | Cite: | Discovery of Small-Molecule Allosteric Inhibitors of Pf ATC as Antimalarials.
J.Am.Chem.Soc., 144, 2022
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7ZGS
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7ZST
 | | Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum in complex with FLA-01 | | Descriptor: | 2-azanyl-~{N}-(2-methoxyethyl)-5-phenyl-thiophene-3-carboxamide, Aspartate carbamoyltransferase, GLYCEROL, ... | | Authors: | Wang, C, Zhang, B, Groves, M.R. | | Deposit date: | 2022-05-08 | | Release date: | 2022-08-24 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Discovery of Small-Molecule Allosteric Inhibitors of Pf ATC as Antimalarials.
J.Am.Chem.Soc., 144, 2022
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7ZID
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7WNT
 | | RNase J from Mycobacterium tuberculosis | | Descriptor: | Ribonuclease J, ZINC ION | | Authors: | Li, J, Bao, L, Hu, J, Zhan, B, Li, Z. | | Deposit date: | 2022-01-19 | | Release date: | 2023-01-25 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.44 Å) | | Cite: | Structural ans functional study of RNase J from Mycobacterium tuberculosis
To Be Published
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7WNU
 | | Mycobacterium tuberculosis Rnase J complex with 7nt RNA | | Descriptor: | RNA (5'-R(P*AP*AP*AP*AP*AP*AP*A)-3'), Ribonuclease J, ZINC ION | | Authors: | Li, J, Hu, J, Bao, L, Zhan, B, Li, Z. | | Deposit date: | 2022-01-19 | | Release date: | 2023-01-25 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural ans functional study of RNase J from Mycobacterium tuberculosis
To Be Published
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4R7A
 | | Crystal Structure of RBBP4 bound to PHF6 peptide | | Descriptor: | GLYCEROL, Histone-binding protein RBBP4, PHD finger protein 6 | | Authors: | Liu, Z, Li, F, Zhang, B, Li, S, Wu, J, Shi, Y. | | Deposit date: | 2014-08-27 | | Release date: | 2015-01-14 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural Basis of Plant Homeodomain Finger 6 (PHF6) Recognition by the Retinoblastoma Binding Protein 4 (RBBP4) Component of the Nucleosome Remodeling and Deacetylase (NuRD) Complex
J.Biol.Chem., 290, 2015
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2ON7
 | | Structure of NaGST-1 | | Descriptor: | Na Glutathione S-transferase 1 | | Authors: | Asojo, O.A, Ngamelue, M, Homma, H, Goud, G, Zhan, B, Hotez, P.J. | | Deposit date: | 2007-01-23 | | Release date: | 2007-08-07 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | X-ray structures of Na-GST-1 and Na-GST-2 two glutathione s-transferase from the human hookworm Necator americanus
Bmc Struct.Biol., 7, 2007
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2ON5
 | | Structure of NaGST-2 | | Descriptor: | 1,2-ETHANEDIOL, GLUTATHIONE, Na Glutathione S-transferase 2 | | Authors: | Asojo, O.A, Ngamelue, M, Homma, H, Goud, G, Zhan, B, Hotez, P.J. | | Deposit date: | 2007-01-23 | | Release date: | 2007-08-07 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | X-ray structures of Na-GST-1 and Na-GST-2 two glutathione s-transferase from the human hookworm Necator americanus
Bmc Struct.Biol., 7, 2007
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8VLU
 | | Cryo-EM structure of human HGSNAT bound with CoA | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COENZYME A, Heparan-alpha-glucosaminide N-acetyltransferase | | Authors: | Li, F, Zhao, B. | | Deposit date: | 2024-01-12 | | Release date: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (3.12 Å) | | Cite: | Structural and mechanistic insights into a lysosomal membrane enzyme HGSNAT involved in Sanfilippo syndrome
To Be Published
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8VLY
 | | Cryo-EM structure of human HGSNAT in transition state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heparan-alpha-glucosaminide N-acetyltransferase | | Authors: | Li, F, Zhao, B. | | Deposit date: | 2024-01-12 | | Release date: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (3.61 Å) | | Cite: | Structural and mechanistic insights into a lysosomal membrane enzyme HGSNAT involved in Sanfilippo syndrome
To Be Published
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8VKJ
 | | Cryo-EM structure of human HGSNAT bound with Acetyl-CoA | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYL COENZYME *A, ... | | Authors: | Li, F, Zhao, B. | | Deposit date: | 2024-01-09 | | Release date: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (2.92 Å) | | Cite: | Structural and mechanistic insights into a lysosomal membrane enzyme HGSNAT involved in Sanfilippo syndrome
To Be Published
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8VLI
 | | Cryo-EM structure of human HGSNAT bound with CoA and product analog | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-methyl-2-oxo-2H-1-benzopyran-7-yl 2-acetamido-2-deoxy-beta-D-glucopyranoside, ... | | Authors: | Li, F, Zhao, B. | | Deposit date: | 2024-01-11 | | Release date: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural and mechanistic insights into a lysosomal membrane enzyme HGSNAT involved in Sanfilippo syndrome
To Be Published
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8VLG
 | | Cryo-EM structure of human HGSNAT bound with Acetyl-CoA and substrate analog | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-methyl-2-oxo-2H-1-benzopyran-7-yl 2-amino-2-deoxy-beta-D-glucopyranoside, ... | | Authors: | Li, F, Zhao, B. | | Deposit date: | 2024-01-11 | | Release date: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (3.15 Å) | | Cite: | Structural and mechanistic insights into a lysosomal membrane enzyme HGSNAT involved in Sanfilippo syndrome
To Be Published
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