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PDB: 80 results

3CM5
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BU of 3cm5 by Molmil
Crystal structure of Cell-Death Related Nuclease 4 (CRN-4) bound with Mn
Descriptor: Cell death-related nuclease 4, MANGANESE (II) ION, ZINC ION
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2008-03-21
Release date:2008-12-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Crystal structure of CRN-4: implications for domain function in apoptotic DNA degradation
Mol.Cell.Biol., 29, 2009
1MVE
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BU of 1mve by Molmil
Crystal structure of a natural circularly-permutated jellyroll protein: 1,3-1,4-beta-D-glucanase from Fibrobacter succinogenes
Descriptor: CALCIUM ION, Truncated 1,3-1,4-beta-D-glucanase
Authors:Tsai, L.-C, Shyur, L.-F, Lee, S.-H, Lin, S.-S, Yuan, H.S.
Deposit date:2002-09-25
Release date:2003-07-15
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of a Natural Circularly Permuted Jellyroll Protein: 1,3-1,4-beta-D-Glucanase from Fibrobacter succinogenes.
J.Mol.Biol., 330, 2003
1MZ8
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BU of 1mz8 by Molmil
CRYSTAL STRUCTURES OF THE NUCLEASE DOMAIN OF COLE7/IM7 IN COMPLEX WITH A PHOSPHATE ION AND A ZINC ION
Descriptor: Colicin E7, Colicin E7 immunity protein, PHOSPHATE ION, ...
Authors:Sui, M.J, Tsai, L.C, Hsia, K.C, Doudeva, L.G, Ku, W.Y, Han, G.W, Yuan, H.S.
Deposit date:2002-10-07
Release date:2002-12-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Metal ions and phosphate binding in the H-N-H motif: crystal structures of the nuclease domain of ColE7/Im7 in complex with a phosphate ion and different divalent metal ions
PROTEIN SCI., 11, 2002
1UNK
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BU of 1unk by Molmil
STRUCTURE OF COLICIN E7 IMMUNITY PROTEIN
Descriptor: COLICIN E7
Authors:Ko, T.-P, Hsieh, S.-Y, Ku, W.-Y, Tseng, M.-Y, Chak, K.-F, Yuan, H.S.
Deposit date:1996-06-21
Release date:1998-01-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A novel role of ImmE7 in the autoregulatory expression of the ColE7 operon and identification of possible RNase active sites in the crystal structure of dimeric ImmE7.
EMBO J., 16, 1997
4QN0
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BU of 4qn0 by Molmil
Crystal structure of the CPS-6 mutant Q130K
Descriptor: Endonuclease G, mitochondrial, MAGNESIUM ION
Authors:Lin, J.L.J, Yuan, H.S.
Deposit date:2014-06-17
Release date:2015-06-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Oxidative Stress Impairs Cell Death by Repressing the Nuclease Activity of Mitochondrial Endonuclease G
Cell Rep, 16, 2016
2IVK
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BU of 2ivk by Molmil
Crystal structure of the periplasmic endonuclease Vvn complexed with a 16-bp DNA
Descriptor: 5'-D(*AP*AP*TP*TP*CP*GP*AP*TP*CP*GP *AP*AP*TP*TP*C)-3', 5'-D(*GP*AP*AP*TP*TP*CP*GP*AP*TP*CP *GP*AP*AP*TP*T)-3', 5'-D(*GP*AP*AP*TP*TP*CP*GP*AP*TP*CP *GP*AP*AP*TP*TP*C)-3', ...
Authors:Wang, Y.T, Yang, W.J, Li, C.L, Doudeva, L.G, Yuan, H.S.
Deposit date:2006-06-14
Release date:2007-01-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Basis for Sequence-Dependent DNA Cleavage by Nonspecific Endonucleases.
Nucleic Acids Res., 35, 2007
2IVH
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BU of 2ivh by Molmil
Crystal structure of the nuclease domain of ColE7 (H545Q mutant) in complex with an 18-bp duplex DNA
Descriptor: 5'-D(*GP*GP*AP*AP*TP*TP*CP*GP*AP*TP *CP*GP*AP*AP*TP*TP*CP*C)-3', COLCIN-E7, ZINC ION
Authors:Wang, Y.T, Yang, W.J, Li, C.L, Doudeva, L.G, Yuan, H.S.
Deposit date:2006-06-13
Release date:2007-01-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for Sequence-Dependent DNA Cleavage by Nonspecific Endonucleases.
Nucleic Acids Res., 35, 2007
2JAZ
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BU of 2jaz by Molmil
CRYSTAL STRUCTURE OF THE MUTANT N560D OF THE NUCLEASE DOMAIN OF COLE7 IN COMPLEX WITH IM7
Descriptor: COLICIN E7, COLICIN E7 IMMUNITY PROTEIN, PHOSPHATE ION, ...
Authors:Huang, H, Yuan, H.S.
Deposit date:2006-12-01
Release date:2007-04-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:The Conserved Asparagine in the Hnh Motif Serves an Important Structural Role in Metal Finger Endonucleases.
J.Mol.Biol., 368, 2007
6IID
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BU of 6iid by Molmil
Human EXOG-H140A in complex with RNA-DNA chimeric duplex
Descriptor: DNA (5'-D(*CP*GP*TP*GP*AP*CP*AP*TP*CP*CP*CP*G)-3'), DNA/RNA (5'-R(P*CP*GP*GP*GP*A)-D(P*T)-R(P*G)-D(P*T)-R(P*CP*AP*CP*G)-3'), MAGNESIUM ION, ...
Authors:Wu, C.C, Lin, J.L.J, Yuan, H.S.
Deposit date:2018-10-04
Release date:2019-04-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.986 Å)
Cite:A unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication.
Nucleic Acids Res., 47, 2019
3FBD
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BU of 3fbd by Molmil
Crystal structure of the nuclease domain of COLE7(D493Q mutant) in complex with an 18-BP duplex DNA
Descriptor: 5'-D(*DGP*DGP*DAP*DAP*DTP*DTP*DCP*DGP*DAP*DTP*DCP*DGP*DAP*DAP*DTP*DTP*DCP*DC)-3', Colicin-E7
Authors:Wang, Y.T, Doudeva, L.G, Yuan, H.S.
Deposit date:2008-11-19
Release date:2009-11-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Redesign of high-affinity nonspecific nucleases with altered sequence preference
To be Published
3HKM
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BU of 3hkm by Molmil
Crystal Structure of rice(Oryza sativa) Rrp46
Descriptor: Os03g0854200 protein
Authors:Yang, C.-C, Wang, Y.-T, Hsiao, Y.-Y, Doudeva, L.G, Yuan, H.S.
Deposit date:2009-05-25
Release date:2010-01-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9845 Å)
Cite:Structural and biochemical characterization of CRN-5 and Rrp46: an exosome component participating in apoptotic DNA degradation
Rna, 16, 2010
3U1K
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BU of 3u1k by Molmil
Crystal structure of human PNPase
Descriptor: CITRIC ACID, Polyribonucleotide nucleotidyltransferase 1, mitochondrial
Authors:Lin, C.L, Yuan, H.S.
Deposit date:2011-09-30
Release date:2012-02-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Crystal structure of human polynucleotide phosphorylase: insights into its domain function in RNA binding and degradation
Nucleic Acids Res., 40, 2012
3TAT
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BU of 3tat by Molmil
TYROSINE AMINOTRANSFERASE FROM E. COLI
Descriptor: PYRIDOXAL-5'-PHOSPHATE, TYROSINE AMINOTRANSFERASE
Authors:Ko, T.P, Yang, W.Z, Wu, S.P, Tsai, H, Yuan, H.S.
Deposit date:1998-08-12
Release date:1999-08-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystallization and preliminary crystallographic analysis of the Escherichia coli tyrosine aminotransferase.
Acta Crystallogr.,Sect.D, 55, 1999
3V9X
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BU of 3v9x by Molmil
Crystal structure of RNase T in complex with a preferred ssDNA (AAA) with two Mg in the active site
Descriptor: DNA (5'-D(*TP*TP*AP*TP*AP*AP*A)-3'), MAGNESIUM ION, Ribonuclease T
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2011-12-28
Release date:2012-07-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes
Nucleic Acids Res., 40, 2012
3VA0
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BU of 3va0 by Molmil
Crystal structure of RNase T in complex with a di-nucleotide product (GG) with one Mg in the active site
Descriptor: COBALT (II) ION, DNA (5'-D(*GP*G)-3'), MAGNESIUM ION, ...
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2011-12-28
Release date:2012-07-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes
Nucleic Acids Res., 40, 2012
5DK5
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BU of 5dk5 by Molmil
Crystal structure of CRN-4-MES complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cell death-related nuclease 4, ISOPROPYL ALCOHOL, ...
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2015-09-03
Release date:2016-08-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Identification of Inhibitors for the DEDDh Family of Exonucleases and a Unique Inhibition Mechanism by Crystal Structure Analysis of CRN-4 Bound with 2-Morpholin-4-ylethanesulfonate (MES)
J.Med.Chem., 59, 2016
4PE8
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BU of 4pe8 by Molmil
Crystal structure of TatD in complex with trinucleotide DNA
Descriptor: DNA (5'-D(*GP*CP*T)-3'), Tat-linked quality control protein TatD
Authors:Chen, Y, Li, C.-L, Hsiao, Y.-Y, Duh, Y, Yuan, H.S.
Deposit date:2014-04-23
Release date:2014-08-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.894 Å)
Cite:Structure and function of TatD exonuclease in DNA repair.
Nucleic Acids Res., 42, 2014
5GKP
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BU of 5gkp by Molmil
Crystal structure of the EndoG worm homologue CPS-6 H148A/F122A in complex with DNA
Descriptor: DNA (5'-D(*TP*TP*TP*TP*T)-3'), Endonuclease G, mitochondrial, ...
Authors:Lin, J.L, Yuan, H.S.
Deposit date:2016-07-05
Release date:2016-11-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of endonuclease G in complex with DNA reveals how it nonspecifically degrades DNA as a homodimer.
Nucleic Acids Res., 44, 2016
5XGU
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BU of 5xgu by Molmil
Escherichia coli. RNase R
Descriptor: MAGNESIUM ION, Ribonuclease R
Authors:Chu, L.Y, Hsieh, T.J, Yuan, H.S.
Deposit date:2017-04-17
Release date:2017-10-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.846 Å)
Cite:Structural insights into RNA unwinding and degradation by RNase R.
Nucleic Acids Res., 45, 2017
3KRN
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BU of 3krn by Molmil
Crystal Structure of C. elegans cell-death-related nuclease 5(CRN-5)
Descriptor: Protein C14A4.5, confirmed by transcript evidence
Authors:Yang, C.-C, Wang, Y.-T, Hsiao, Y.-Y, Doudeva, L.G, Chow, S.Y, Yuan, H.S.
Deposit date:2009-11-19
Release date:2010-01-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.918 Å)
Cite:Structural and biochemical characterization of CRN-5 and Rrp46: an exosome component participating in apoptotic DNA degradation
Rna, 16, 2010
3NH2
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BU of 3nh2 by Molmil
Crystal structure of RNase T in complex with a stem DNA with a 3' overhang
Descriptor: 5'-D(P*TP*TP*AP*CP*AP*AP*C)-3', Ribonuclease T
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2010-06-14
Release date:2011-02-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation
Nat.Chem.Biol., 7, 2011
3NH0
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BU of 3nh0 by Molmil
Crystal structure of RNase T in complex with a non-preferred ssDNA (AAC)
Descriptor: 5'-D(*TP*TP*AP*CP*AP*AP*C)-3', Ribonuclease T
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2010-06-14
Release date:2011-02-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation
Nat.Chem.Biol., 7, 2011
3NGZ
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BU of 3ngz by Molmil
Crystal structure of RNase T in complex with a non-preferred ssDNA (GC) with one Mg in the active site
Descriptor: 5'-D(P*GP*C)-3', COBALT (II) ION, MAGNESIUM ION, ...
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2010-06-14
Release date:2011-02-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation
Nat.Chem.Biol., 7, 2011
3NGY
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BU of 3ngy by Molmil
Crystal structure of RNase T (E92G mutant)
Descriptor: COBALT (II) ION, Ribonuclease T, his tag sequence
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2010-06-14
Release date:2011-02-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.204 Å)
Cite:Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation
Nat.Chem.Biol., 7, 2011
3NH1
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BU of 3nh1 by Molmil
Crystal structure of RNase T in complex with a preferred ssDNA (TAGG) with two Mg in the active site
Descriptor: 5'-D(*TP*TP*AP*TP*AP*GP*G)-3', MAGNESIUM ION, Ribonuclease T
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2010-06-14
Release date:2011-02-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.107 Å)
Cite:Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation
Nat.Chem.Biol., 7, 2011

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