2IVH

Crystal structure of the nuclease domain of ColE7 (H545Q mutant) in complex with an 18-bp duplex DNA

Summary for 2IVH

• Entry DOI: 10.2210/pdb2ivh/pdb
• Related: 1M08 1MZ8 1PT3 1UJZ 1ZNS 1ZNV 2AXC 7CEI
• Descriptor: COLCIN-E7, 5'-D(*GP*GP*AP*AP*TP*TP*CP*GP*AP*TP *CP*GP*AP*AP*TP*TP*CP*C)-3', ZINC ION, ... (4 entities in total)
• Functional Keywords: bacteriocin, endonuclease, antimicrobial, metal-binding, hydrolase-dna complex, zinc, plasmid, nuclease, hydrolase, antibiotic
• Biological source: ESCHERICHIA COLI; More
• Total number of polymer chains: 3
• Total formula weight: 25748.20

Authors

Wang, Y.T.,Yang, W.J.,Li, C.L.,Doudeva, L.G.,Yuan, H.S. (deposition date: 2006-06-13, release date: 2007-01-02, Last modification date: 2023-12-13)

• Primary citation: Wang, Y.T.,Yang, W.J.,Li, C.L.,Doudeva, L.G.,Yuan, H.S.; Structural Basis for Sequence-Dependent DNA Cleavage by Nonspecific Endonucleases.; Nucleic Acids Res., 35:584-, 2007; PubMed: 17175542; DOI: 10.1093/NAR/GKL621

Experimental method

X-RAY DIFFRACTION (2.8 Å)