5GKP

Crystal structure of the EndoG worm homologue CPS-6 H148A/F122A in complex with DNA

Summary for 5GKP

• Entry DOI: 10.2210/pdb5gkp/pdb
• Related: 5GKC
• Descriptor: Endonuclease G, mitochondrial, DNA (5'-D(*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: endog, mitochondria, endonuclease, non-specific nuclease, protein-dna interactions, hydrolase-dna complex, hydrolase/dna
• Biological source: Caenorhabditis elegans; More
• Cellular location: Mitochondrion : Q95NM6
• Total number of polymer chains: 4
• Total formula weight: 62271.25

Authors

Lin, J.L.,Yuan, H.S. (deposition date: 2016-07-05, release date: 2016-11-23, Last modification date: 2023-11-08)

• Primary citation: Lin, J.L.,Wu, C.C.,Yang, W.Z.,Yuan, H.S.; Crystal structure of endonuclease G in complex with DNA reveals how it nonspecifically degrades DNA as a homodimer.; Nucleic Acids Res., 44:10480-10490, 2016; PubMed: 27738134; DOI: 10.1093/nar/gkw931

Experimental method

X-RAY DIFFRACTION (2.3 Å)