3KNV
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3HCS
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![BU of 3hcs by Molmil](/molmil-images/mine/3hcs) | Crystal structure of the N-terminal domain of TRAF6 | Descriptor: | TNF receptor-associated factor 6, ZINC ION | Authors: | Yin, Q, Lin, S.-C, Lamothe, B, Lu, M, Lo, Y.-C, Hura, G, Zheng, L, Rich, R.L, Campos, A.D, Myszka, D.G, Lenardo, M.J, Darnay, B.G, Wu, H. | Deposit date: | 2009-05-06 | Release date: | 2009-05-26 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | E2 interaction and dimerization in the crystal structure of TRAF6. Nat.Struct.Mol.Biol., 16, 2009
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3HCU
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![BU of 3hcu by Molmil](/molmil-images/mine/3hcu) | Crystal structure of TRAF6 in complex with Ubc13 in the C2 space group | Descriptor: | TNF receptor-associated factor 6, Ubiquitin-conjugating enzyme E2 N, ZINC ION | Authors: | Yin, Q, Lin, S.-C, Lamothe, B, Lu, M, Lo, Y.-C, Hura, G, Zheng, L, Rich, R.L, Campos, A.D, Myszka, D.G, Lenardo, M.J, Darnay, B.G, Wu, H. | Deposit date: | 2009-05-06 | Release date: | 2009-05-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | E2 interaction and dimerization in the crystal structure of TRAF6. Nat.Struct.Mol.Biol., 16, 2009
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3HCT
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![BU of 3hct by Molmil](/molmil-images/mine/3hct) | Crystal structure of TRAF6 in complex with Ubc13 in the P1 space group | Descriptor: | TNF receptor-associated factor 6, Ubiquitin-conjugating enzyme E2 N, ZINC ION | Authors: | Yin, Q, Lin, S.-C, Lamothe, B, Lu, M, Lo, Y.-C, Hura, G, Zheng, L, Rich, R.L, Campos, A.D, Myszka, D.G, Lenardo, M.J, Darnay, B.G, Wu, H. | Deposit date: | 2009-05-06 | Release date: | 2009-05-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | E2 interaction and dimerization in the crystal structure of TRAF6. Nat.Struct.Mol.Biol., 16, 2009
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7TDQ
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4L5T
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![BU of 4l5t by Molmil](/molmil-images/mine/4l5t) | Crystal structure of the tetrameric p202 HIN2 | Descriptor: | Interferon-activable protein 202 | Authors: | Yin, Q, Tian, Y, Wu, H. | Deposit date: | 2013-06-11 | Release date: | 2013-07-31 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.405 Å) | Cite: | Molecular Mechanism for p202-Mediated Specific Inhibition of AIM2 Inflammasome Activation. Cell Rep, 4, 2013
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4L5R
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4L5Q
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![BU of 4l5q by Molmil](/molmil-images/mine/4l5q) | Crystal structure of p202 HIN1 | Descriptor: | Interferon-activable protein 202 | Authors: | Yin, Q, Tian, Y, Wu, H. | Deposit date: | 2013-06-11 | Release date: | 2013-07-31 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Molecular Mechanism for p202-Mediated Specific Inhibition of AIM2 Inflammasome Activation. Cell Rep, 4, 2013
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4L5S
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![BU of 4l5s by Molmil](/molmil-images/mine/4l5s) | p202 HIN1 in complex with 12-mer dsDNA | Descriptor: | 12-mer DNA, Interferon-activable protein 202, SULFATE ION | Authors: | Yin, Q, Tian, Y, Wu, H. | Deposit date: | 2013-06-11 | Release date: | 2013-08-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.94 Å) | Cite: | Molecular Mechanism for p202-Mediated Specific Inhibition of AIM2 Inflammasome Activation. Cell Rep, 4, 2013
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3JBL
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![BU of 3jbl by Molmil](/molmil-images/mine/3jbl) | Cryo-EM Structure of the Activated NAIP2/NLRC4 Inflammasome Reveals Nucleated Polymerization | Descriptor: | NLR family CARD domain-containing protein 4 | Authors: | Zhang, L, Chen, S, Ruan, J, Wu, J, Tong, A.B, Yin, Q, Li, Y, David, L, Lu, A, Wang, W.L, Marks, C, Ouyang, Q, Zhang, X, Mao, Y, Wu, H. | Deposit date: | 2015-09-05 | Release date: | 2015-10-21 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization. Science, 350, 2015
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6VKJ
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6OE9
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![BU of 6oe9 by Molmil](/molmil-images/mine/6oe9) | Crystal structure of p204 HIN1 domain | Descriptor: | GLYCEROL, Interferon-activable protein 204, SULFATE ION | Authors: | Tian, Y, Yin, Q. | Deposit date: | 2019-03-27 | Release date: | 2019-07-10 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Structural analysis of the HIN1 domain of interferon-inducible protein 204. Acta Crystallogr.,Sect.F, 75, 2019
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3J63
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![BU of 3j63 by Molmil](/molmil-images/mine/3j63) | Unified assembly mechanism of ASC-dependent inflammasomes | Descriptor: | Apoptosis-associated speck-like protein containing a CARD | Authors: | Lu, A, Magupalli, V.G, Ruan, J, Yin, Q, Atianand, M.K, Vos, M, Schroder, G.F, Fitzgerald, K.A, Wu, H, Egelman, E.H. | Deposit date: | 2013-12-05 | Release date: | 2014-03-26 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes. Cell(Cambridge,Mass.), 156, 2014
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7M1S
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![BU of 7m1s by Molmil](/molmil-images/mine/7m1s) | |
7TWD
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![BU of 7twd by Molmil](/molmil-images/mine/7twd) | Structure of AAGAB C-terminal dimerization domain | Descriptor: | Alpha- and gamma-adaptin-binding protein p34, PHOSPHATE ION | Authors: | Tian, Y, Yin, Q. | Deposit date: | 2022-02-07 | Release date: | 2023-01-18 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Oligomer-to-monomer transition underlies the chaperone function of AAGAB in AP1/AP2 assembly. Proc.Natl.Acad.Sci.USA, 120, 2023
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5FNA
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![BU of 5fna by Molmil](/molmil-images/mine/5fna) | Cryo-EM reconstruction of caspase-1 CARD | Descriptor: | Caspase-1 | Authors: | Li, Y, Lu, A, Schmidt, F.I, Yin, Q, Chen, S, Fu, T.M, Tong, A.B, Ploegh, H.L, Mao, Y, Wu, H. | Deposit date: | 2015-11-11 | Release date: | 2016-03-30 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Molecular Basis of Caspase-1 Polymerization and its Inhibition by a Novel Capping Mechanism Nat.Struct.Mol.Biol., 23, 2016
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7LV3
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![BU of 7lv3 by Molmil](/molmil-images/mine/7lv3) | Crystal structure of human protein kinase G (PKG) R-C complex in inhibited state | Descriptor: | 1,2-ETHANEDIOL, Isoform Beta of cGMP-dependent protein kinase 1, MANGANESE (II) ION, ... | Authors: | Sharma, R, Lying, Q, Casteel, D, Kim, C. | Deposit date: | 2021-02-23 | Release date: | 2022-08-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | An auto-inhibited state of protein kinase G and implications for selective activation. Elife, 11, 2022
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