8XWX
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6QWU
| 4'-phosphopantetheinyl transferase PptAb from Mycobacterium abscessus at pH 5.5 with Mn2+ and CoA. | 分子名称: | COENZYME A, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, ... | 著者 | Nguyen, M.C, Mourey, L, Pedelacq, J.D. | 登録日 | 2019-03-06 | 公開日 | 2020-03-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Conformational flexibility of coenzyme A and its impact on the post-translational modification of acyl carrier proteins by 4'-phosphopantetheinyl transferases. Febs J., 287, 2020
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6QXQ
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6QYF
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6QYG
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6RCX
| Mycobacterial 4'-phosphopantetheinyl transferase PptAb in complex with the ACP domain of PpsC. | 分子名称: | CACODYLATE ION, COENZYME A, MANGANESE (II) ION, ... | 著者 | Nguyen, M.C, Mourey, L, Pedelacq, J.D. | 登録日 | 2019-04-12 | 公開日 | 2020-04-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Conformational flexibility of coenzyme A and its impact on the post-translational modification of acyl carrier proteins by 4'-phosphopantetheinyl transferases. Febs J., 287, 2020
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6QXR
| 4'-phosphopantetheinyl transferase PptAb from Mycobacterium abscessus at pH 8.5 with Mn2+ and CoA. | 分子名称: | CALCIUM ION, COENZYME A, MANGANESE (II) ION, ... | 著者 | Nguyen, M.C, Mourey, L, Pedelacq, J.D. | 登録日 | 2019-03-07 | 公開日 | 2020-03-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Conformational flexibility of coenzyme A and its impact on the post-translational modification of acyl carrier proteins by 4'-phosphopantetheinyl transferases. Febs J., 287, 2020
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7S2S
| nanobody bound to Interleukin-2Rbeta | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, IL2Rb-binding nanobody, Interleukin-2 receptor subunit beta, ... | 著者 | Glassman, C.R, Jude, K.M, Yen, M, Garcia, K.C. | 登録日 | 2021-09-03 | 公開日 | 2022-03-30 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Facile discovery of surrogate cytokine agonists. Cell, 185, 2022
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7S2R
| nanobody bound to IL-2Rg | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit gamma, ... | 著者 | Glassman, C.R, Jude, K.M, Yen, M, Garcia, K.C. | 登録日 | 2021-09-03 | 公開日 | 2022-03-30 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Facile discovery of surrogate cytokine agonists. Cell, 185, 2022
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8OP0
| VHH Z70 mutant 20 in interaction with PHF6 Tau peptide | 分子名称: | Tau PHF6 peptide, VHH Z70 mutant 20 | 著者 | Dupre, E, Mortelecque, J, NGuyen, M, Hanoulle, X, Landrieu, I. | 登録日 | 2023-04-06 | 公開日 | 2023-05-31 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered protein. J.Biol.Chem., 300, 2024
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8PII
| VHH Z70 mutant 3 in interaction with PHF6 Tau peptide | 分子名称: | Microtubule-associated protein tau, VHH Z70 Mutant 3 | 著者 | Dupre, E, Mortelecque, J, NGuyen, M, Hanoulle, X, Landrieu, I. | 登録日 | 2023-06-21 | 公開日 | 2023-07-05 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered protein. J.Biol.Chem., 300, 2024
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8OPI
| VHH Z70 mutant 1 in interaction with PHF6 Tau peptide | 分子名称: | PHF6 Tau peptide, VHH Z70 mutant 1 | 著者 | Dupre, E, Mortelecque, J, NGuyen, M, Hanoulle, X, Landrieu, I. | 登録日 | 2023-04-07 | 公開日 | 2023-05-31 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered protein. J.Biol.Chem., 300, 2024
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4XRT
| Crystal structure of the di-domain ARO/CYC StfQ from the steffimycin biosynthetic pathway | 分子名称: | FORMIC ACID, StfQ Aromatase/Cyclase | 著者 | Tsai, S.C, Caldara-Festin, G.M, Jackson, D.R, Aguilar, S, Patel, A, Nguyen, M, Sasaki, E, Valentic, T.R, Barajas, J.F, Vo, M, Khanna, A, Liu, H.-W. | 登録日 | 2015-01-21 | 公開日 | 2015-12-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.952 Å) | 主引用文献 | Structural and functional analysis of two di-domain aromatase/cyclases from type II polyketide synthases. Proc.Natl.Acad.Sci.USA, 112, 2015
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4XRW
| Crystal structure of the di-domain ARO/CYC BexL from the BE-7585A biosynthetic pathway | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BexL | 著者 | Tsai, S.C, Caldara-Festin, G.M, Jackson, D.R, Aguilar, S, Patel, A, Nguyen, M, Sasaki, E, Valentic, T.R, Barajas, J.F, Vo, M, Khanna, A, Liu, H.-W. | 登録日 | 2015-01-21 | 公開日 | 2015-12-02 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Structural and functional analysis of two di-domain aromatase/cyclases from type II polyketide synthases. Proc.Natl.Acad.Sci.USA, 112, 2015
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5MTF
| A modular route to novel potent and selective inhibitors of rhomboid intramembrane proteases | 分子名称: | CHLORIDE ION, Rhomboid protease GlpG, inhibitor, ... | 著者 | Ticha, A, Stanchev, S, Vinothkumar, K.R, Mikles, D.C, Pachl, P, Svehlova, K, Nguyen, M.T.N, Verhelst, S.H.L, Johnson, D, Bachovchin, D, Lepsik, M, Majer, P, Strisovsky, K. | 登録日 | 2017-01-09 | 公開日 | 2017-11-15 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | General and Modular Strategy for Designing Potent, Selective, and Pharmacologically Compliant Inhibitors of Rhomboid Proteases. Cell Chem Biol, 24, 2017
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7UNN
| Thiol-disulfide oxidoreductase TsdA from Corynebacterium diphtheriae | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Thioredoxin domain-containing protein | 著者 | Osipiuk, J, Reardon-Robinson, M, Nguyen, M.T, Sanchez, B, Ton-That, H, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2022-04-11 | 公開日 | 2022-04-20 | 最終更新日 | 2023-05-17 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | A cryptic oxidoreductase safeguards oxidative protein folding in Corynebacterium diphtheriae. Proc.Natl.Acad.Sci.USA, 120, 2023
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7UNO
| Thiol-disulfide oxidoreductase TsdA, C129S mutant, from Corynebacterium diphtheriae | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, TRIETHYLENE GLYCOL, ... | 著者 | Osipiuk, J, Reardon-Robinson, M, Nguyen, M.T, Sanchez, B, Ton-That, H, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2022-04-11 | 公開日 | 2022-04-20 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Thiol-disulfide oxidoreductase in Corynebacterium diphtheriae To Be Published
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4WV3
| Crystal structure of the anthranilate CoA ligase AuaEII in complex with anthranoyl-AMP | 分子名称: | 5'-O-[(S)-[(2-aminobenzoyl)oxy](hydroxy)phosphoryl]adenosine, Anthranilate-CoA ligase | 著者 | Tsai, S.C, Muller, R, Jackson, D.R, Tu, S.S, Nguyen, M, Barajas, J.F, Pistorious, D, Krug, D. | 登録日 | 2014-11-04 | 公開日 | 2015-11-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.599 Å) | 主引用文献 | Structural Insights into Anthranilate Priming during Type II Polyketide Biosynthesis. Acs Chem.Biol., 11, 2016
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3J4B
| Structure of T7 gatekeeper protein (gp11) | 分子名称: | Tail tubular protein A | 著者 | Cuervo, A, Pulido-Cid, M, Chagoyen, M, Arranz, R, Gonzalez-Garcia, V.A, Garcia-Doval, C, Caston, J.R, Valpuesta, J.M, van Raaij, M.J, Martin-Benito, J, Carrascosa, J.L. | 登録日 | 2013-07-09 | 公開日 | 2013-08-07 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (12 Å) | 主引用文献 | Structural characterization of the bacteriophage t7 tail machinery. J.Biol.Chem., 288, 2013
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3J4A
| Structure of gp8 connector protein | 分子名称: | Head-to-tail joining protein | 著者 | Cuervo, A, Pulido-Cid, M, Chagoyen, M, Arranz, R, Gonzalez-Garcia, V.A, Garcia-Doval, C, Caston, J.R, Valpuesta, J.M, van Raaij, M.J, Martin-Benito, J, Carrascosa, J.L. | 登録日 | 2013-07-09 | 公開日 | 2013-08-07 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (12 Å) | 主引用文献 | Structural characterization of the bacteriophage t7 tail machinery. J.Biol.Chem., 288, 2013
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1EQ9
| CRYSTAL STRUCTURE OF FIRE ANT CHYMOTRYPSIN COMPLEXED TO PMSF | 分子名称: | CHYMOTRYPSIN, phenylmethanesulfonic acid | 著者 | Botos, I, Meyer, E, Nguyen, M.H, Swanson, S.M, Meyer, E.F. | 登録日 | 2000-04-03 | 公開日 | 2000-10-03 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The structure of an insect chymotrypsin. J.Mol.Biol., 298, 2000
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1MRN
| CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS THYMIDYLATE KINASE COMPLEXED WITH BISUBSTRATE INHIBITOR (TP5A) | 分子名称: | MAGNESIUM ION, P1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE, SULFATE ION, ... | 著者 | Haouz, A, Vanheusden, V, Munier-Lehmann, H, Froeyen, M, Herdewijn, P, Van Calenbergh, S, Delarue, M. | 登録日 | 2002-09-18 | 公開日 | 2003-01-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Enzymatic and structural analysis of inhibitors designed against Mycobacterium tuberculosis thymidylate kinase. New insights into the phosphoryl transfer mechanism. J.Biol.Chem., 278, 2003
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1N2Y
| SOLUTION STRUCTURE OF SS-CYCLIZED CATESTATIN FRAGMENT FROM CHROMOGRANIN A | 分子名称: | CATESTATIN | 著者 | Preece, N.E, Nguyen, M, Mahata, M, Mahata, S.K, Mahapatra, N.R, Tsigelny, I, O'Connor, D.T. | 登録日 | 2002-10-24 | 公開日 | 2002-11-13 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Conformational preferences and activities of peptides from the catecholamine
release-inhibitory (catestatin) region of chromogranin A Regul.Pept., 118, 2004
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7BDW
| Crystal structure of mycobacterial PptAb in complex with ACP and compound 8918 | 分子名称: | COENZYME A, MANGANESE (II) ION, N-(2,6-diethylphenyl)-N'-(N-ethylcarbamimidoyl)urea, ... | 著者 | Carivenc, C, Nguyen, M.C, Mourey, L, Pedelacq, J.D. | 登録日 | 2020-12-22 | 公開日 | 2021-11-10 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Phosphopantetheinyl transferase binding and inhibition by amidino-urea and hydroxypyrimidinethione compounds. Sci Rep, 11, 2021
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3HEI
| Ligand Recognition by A-Class Eph Receptors: Crystal Structures of the EphA2 Ligand-Binding Domain and the EphA2/ephrin-A1 Complex | 分子名称: | Ephrin type-A receptor 2, Ephrin-A1 | 著者 | Himanen, J.P, Goldgur, Y, Miao, H, Myshkin, E, Guo, H, Buck, M, Nguyen, M, Rajashankar, K.R, Wang, B, Nikolov, D.B. | 登録日 | 2009-05-08 | 公開日 | 2009-06-30 | 最終更新日 | 2021-03-31 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex. Embo Rep., 10, 2009
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