4WV3

Crystal structure of the anthranilate CoA ligase AuaEII in complex with anthranoyl-AMP

Summary for 4WV3

Entry DOI	10.2210/pdb4wv3/pdb
Descriptor	Anthranilate-CoA ligase, 5'-O-[(S)-[(2-aminobenzoyl)oxy](hydroxy)phosphoryl]adenosine (3 entities in total)
Functional Keywords	anthranilate, coa ligase, aurachin, natural product biosynthesis, ligase-ligase inhibitor complex, ligase/ligase inhibitor
Biological source	Stigmatella aurantiaca
Total number of polymer chains	2
Total formula weight	118284.35
Authors	Tsai, S.C.,Muller, R.,Jackson, D.R.,Tu, S.S.,Nguyen, M.,Barajas, J.F.,Pistorious, D.,Krug, D. (deposition date: 2014-11-04, release date: 2015-11-11, Last modification date: 2023-09-27)
Primary citation	Jackson, D.R.,Tu, S.S.,Nguyen, M.,Barajas, J.F.,Schaub, A.J.,Krug, D.,Pistorius, D.,Luo, R.,Muller, R.,Tsai, S.C. Structural Insights into Anthranilate Priming during Type II Polyketide Biosynthesis. Acs Chem.Biol., 11:95-103, 2016 Cited by PubMed: 26473393 DOI: 10.1021/acschembio.5b00500 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.599 Å)

Structure validation