8PII
VHH Z70 mutant 3 in interaction with PHF6 Tau peptide
Summary for 8PII
| Entry DOI | 10.2210/pdb8pii/pdb |
| Related | 7qcq 8op0 8opi |
| Descriptor | VHH Z70 Mutant 3, Microtubule-associated protein tau (3 entities in total) |
| Functional Keywords | vhh, nanobody, complex, tau, immune system |
| Biological source | Lama glama More |
| Total number of polymer chains | 2 |
| Total formula weight | 15204.76 |
| Authors | Dupre, E.,Mortelecque, J.,NGuyen, M.,Hanoulle, X.,Landrieu, I. (deposition date: 2023-06-21, release date: 2023-07-05, Last modification date: 2024-04-24) |
| Primary citation | Mortelecque, J.,Zejneli, O.,Begard, S.,Simoes, M.C.,ElHajjar, L.,Nguyen, M.,Cantrelle, F.X.,Hanoulle, X.,Rain, J.C.,Colin, M.,Gomes, C.M.,Buee, L.,Landrieu, I.,Danis, C.,Dupre, E. A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered protein. J.Biol.Chem., 300:107163-107163, 2024 Cited by PubMed: 38484799DOI: 10.1016/j.jbc.2024.107163 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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