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PDB: 18 件
6SKL
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BU of 6skl by Molmil
Cryo-EM structure of the CMG Fork Protection Complex at a replication fork - Conformation 1
分子名称: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA fork, ...
著者Yeeles, J, Baretic, D, Jenkyn-Bedford, M.
登録日2019-08-16
公開日2020-05-06
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM Structure of the Fork Protection Complex Bound to CMG at a Replication Fork.
Mol.Cell, 78, 2020
6SKO
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BU of 6sko by Molmil
Cryo-EM Structure of the Fork Protection Complex Bound to CMG at a Replication Fork - conformation 2 MCM CTD:ssDNA
分子名称: DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, DNA replication licensing factor MCM4, ...
著者Yeeles, J, Baretic, D, Jenkyn-Bedford, M.
登録日2019-08-16
公開日2020-05-06
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM Structure of the Fork Protection Complex Bound to CMG at a Replication Fork.
Mol.Cell, 78, 2020
8OUW
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BU of 8ouw by Molmil
Cryo-EM structure of CMG helicase bound to TIM-1/TIPN-1 and homodimeric DNSN-1 on fork DNA (Caenorhabditis elegans)
分子名称: Cell division control protein 45 homolog, DNA Lagging Strand Template, DNA Leading Strand Template, ...
著者Jenkyn-Bedford, M, Yeeles, J.T.P, Labib, K.P.M.
登録日2023-04-25
公開日2023-08-16
最終更新日2023-10-04
実験手法ELECTRON MICROSCOPY (3.75 Å)
主引用文献DNSN-1 recruits GINS for CMG helicase assembly during DNA replication initiation in Caenorhabditis elegans.
Science, 381, 2023
8B9D
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BU of 8b9d by Molmil
Human replisome bound by Pol Alpha
分子名称: Cell division control protein 45 homolog, Claspin, DNA Molecule, ...
著者Jones, M.L, Yeeles, J.T.P.
登録日2022-10-05
公開日2023-08-09
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication.
Mol.Cell, 83, 2023
8B9C
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BU of 8b9c by Molmil
S. cerevisiae pol alpha - replisome complex
分子名称: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha catalytic subunit A, ...
著者Jones, M.L, Yeeles, J.T.P.
登録日2022-10-05
公開日2023-08-09
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication.
Mol.Cell, 83, 2023
8B9B
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BU of 8b9b by Molmil
S. cerevisiae replisome + Ctf4, bound by pol alpha. Complex engaged with a fork DNA substrate containing a 60 nucleotide lagging strand.
分子名称: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha catalytic subunit A, ...
著者Jones, M.L, Yeeles, J.T.P.
登録日2022-10-05
公開日2023-08-09
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication.
Mol.Cell, 83, 2023
8B9A
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BU of 8b9a by Molmil
S. cerevisiae replisome + Ctf4, bound by pol alpha primase. Complex engaged with a fork DNA substrate containing a 60 nucleotide lagging strand.
分子名称: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha catalytic subunit A, ...
著者Jones, M.L, Yeeles, J.T.P.
登録日2022-10-05
公開日2023-08-09
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication.
Mol.Cell, 83, 2023
7PFO
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BU of 7pfo by Molmil
Core human replisome
分子名称: Cell division control protein 45 homolog, Claspin, DNA polymerase epsilon catalytic subunit A, ...
著者Jones, M.J, Yeeles, J.T.P.
登録日2021-08-11
公開日2021-11-10
最終更新日2023-10-18
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of a human replisome shows the organisation and interactions of a DNA replication machine.
Embo J., 40, 2021
7PMK
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BU of 7pmk by Molmil
S. cerevisiae replisome-SCF(Dia2) complex bound to double-stranded DNA (conformation I)
分子名称: Cell division control protein 45,Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA helicase, ...
著者Jenkyn-Bedford, M, Yeeles, J.T.P, Deegan, T.D.
登録日2021-09-02
公開日2021-11-10
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献A conserved mechanism for regulating replisome disassembly in eukaryotes.
Nature, 600, 2021
7PMN
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BU of 7pmn by Molmil
S. cerevisiae replisome-SCF(Dia2) complex bound to double-stranded DNA (conformation II)
分子名称: Cell division control protein 45,Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha-binding protein, ...
著者Jenkyn-Bedford, M, Yeeles, J.T.P, Deegan, T.D.
登録日2021-09-02
公開日2021-11-10
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献A conserved mechanism for regulating replisome disassembly in eukaryotes.
Nature, 600, 2021
7PLO
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BU of 7plo by Molmil
H. sapiens replisome-CUL2/LRR1 complex
分子名称: Cell division control protein 45 homolog, Claspin, Cullin-2, ...
著者Jones, M.J, Yeeles, J.T.P, Deegan, T.D, Jenkyn-Bedford, M.
登録日2021-09-01
公開日2021-11-10
最終更新日2023-10-18
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献A conserved mechanism for regulating replisome disassembly in eukaryotes.
Nature, 600, 2021
9F6D
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BU of 9f6d by Molmil
Human DNA polymerase epsilon bound to DNA and PCNA (open conformation)
分子名称: 2',3'-dideoxyadenosine triphosphate, DNA nascent strand, DNA polymerase epsilon catalytic subunit A, ...
著者Roske, J.J, Yeeles, J.T.P.
登録日2024-05-01
公開日2024-08-07
最終更新日2024-08-21
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon.
Nat.Struct.Mol.Biol., 2024
9F6L
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BU of 9f6l by Molmil
Human DNA Polymerase epsilon bound to T-C mismatched DNA (Mismatch Excision state)
分子名称: CALCIUM ION, DNA nascent strand, DNA polymerase epsilon catalytic subunit A, ...
著者Roske, J.J, Yeeles, J.T.P.
登録日2024-05-01
公開日2024-08-07
最終更新日2024-08-21
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon.
Nat.Struct.Mol.Biol., 2024
9F6I
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BU of 9f6i by Molmil
Human DNA Polymerase epsilon bound to T-C mismatched DNA (Post-Insertion state)
分子名称: 2',3'-dideoxyadenosine triphosphate, CALCIUM ION, DNA nascent strand, ...
著者Roske, J.J, Yeeles, J.T.P.
登録日2024-05-01
公開日2024-08-07
最終更新日2024-08-21
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon.
Nat.Struct.Mol.Biol., 2024
9F6J
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BU of 9f6j by Molmil
Human DNA Polymerase epsilon bound to T-C mismatched DNA (Polymerase Arrest state)
分子名称: DNA nascent strand, DNA polymerase epsilon catalytic subunit A, DNA template strand, ...
著者Roske, J.J, Yeeles, J.T.P.
登録日2024-05-01
公開日2024-08-07
最終更新日2024-08-21
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon.
Nat.Struct.Mol.Biol., 2024
9F6F
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BU of 9f6f by Molmil
Human DNA polymerase epsilon bound to DNA and PCNA (closed conformation)
分子名称: 2',3'-dideoxyadenosine triphosphate, DNA nascent strand, DNA polymerase epsilon catalytic subunit A, ...
著者Roske, J.J, Yeeles, J.T.P.
登録日2024-05-01
公開日2024-08-07
最終更新日2024-08-21
実験手法ELECTRON MICROSCOPY (3.75 Å)
主引用文献Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon.
Nat.Struct.Mol.Biol., 2024
9F6K
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BU of 9f6k by Molmil
Human DNA Polymerase epsilon bound to T-C mismatched DNA (Frayed Substrate state)
分子名称: DNA nascent strand, DNA polymerase epsilon catalytic subunit A, DNA template strand, ...
著者Roske, J.J, Yeeles, J.T.P.
登録日2024-05-01
公開日2024-08-07
最終更新日2024-08-21
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon.
Nat.Struct.Mol.Biol., 2024
9F6E
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BU of 9f6e by Molmil
Human DNA polymerase epsilon bound to DNA and PCNA (ajar conformation)
分子名称: 2',3'-dideoxyadenosine triphosphate, DNA nascent strand, DNA polymerase epsilon catalytic subunit A, ...
著者Roske, J.J, Yeeles, J.T.P.
登録日2024-05-01
公開日2024-08-07
最終更新日2024-08-21
実験手法ELECTRON MICROSCOPY (3.74 Å)
主引用文献Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon.
Nat.Struct.Mol.Biol., 2024

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件を2024-09-04に公開中

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