1F9Q
 
 | | CRYSTAL STRUCTURE OF PLATELET FACTOR 4 | | Descriptor: | PLATELET FACTOR 4 | | Authors: | Yang, J, Doyle, M, Faulk, T, Visentin, G, Aster, R, Edwards, B. | | Deposit date: | 2000-07-11 | | Release date: | 2003-08-26 | | Last modified: | 2017-10-04 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure Comparison of Two Platelet Factor 4 Mutants with the Wild-Type Reveals the Epitopes for the Heparin-Induced Thrombocytopenia Antibodies
To be Published
|
|
1F9R
 | | CRYSTAL STRUCTURE OF PLATELET FACTOR 4 MUTANT 1 | | Descriptor: | PLATELET FACTOR 4 | | Authors: | Yang, J, Doyle, M, Faulk, T, Visentin, G, Aster, R, Edwards, B. | | Deposit date: | 2000-07-11 | | Release date: | 2003-08-26 | | Last modified: | 2021-11-03 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure Comparison of Two Platelet Factor 4 Mutants with the Wild-type Reveals the Epitopes for the Heparin-induced Thrombocytopenia Antibodies
To be Published
|
|
1FPR
 | | CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN THE CATALYTIC DOMAIN OF SHP-1 AND AN IN VITRO PEPTIDE SUBSTRATE PY469 DERIVED FROM SHPS-1. | | Descriptor: | PEPTIDE PY469, PROTEIN-TYROSINE PHOSPHATASE 1C | | Authors: | Yang, J, Cheng, Z, Niu, Z, Zhao, Z.J, Zhou, G.W. | | Deposit date: | 2000-08-31 | | Release date: | 2001-03-07 | | Last modified: | 2021-11-03 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural basis for substrate specificity of protein-tyrosine phosphatase SHP-1.
J.Biol.Chem., 275, 2000
|
|
1F9P
 | | CRYSTAL STRUCTURE OF CONNECTIVE TISSUE ACTIVATING PEPTIDE-III(CTAP-III) COMPLEXED WITH POLYVINYLSULFONIC ACID | | Descriptor: | CONNECTIVE TISSUE ACTIVATING PEPTIDE-III, ETHANESULFONIC ACID | | Authors: | Yang, J, Faulk, T, Aster, R, Visentin, G, Edwards, B, Castor, C. | | Deposit date: | 2000-07-11 | | Release date: | 2003-08-26 | | Last modified: | 2017-10-04 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Structure of the CXC Chemokine, Connective Tissue Activating Peptide-III, Complexed with the Heparin Analogue, Polyvinylsulfonic Acid
To be Published
|
|
1F9S
 | | CRYSTAL STRUCTURE OF PLATELET FACTOR 4 MUTANT 2 | | Descriptor: | PLATELET FACTOR 4 | | Authors: | Yang, J, Doyle, M, Faulk, T, Visentin, G, Aster, R, Edwards, B. | | Deposit date: | 2000-07-11 | | Release date: | 2003-08-26 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.38 Å) | | Cite: | Structure Comparison of Two Platelet Factor 4 Mutants with the Wild-type Reveals the Epitopes for the Heparin-induced Thrombocytopenia Antibodies
To be Published
|
|
1GWZ
 | | CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THE PROTEIN TYROSINE PHOSPHATASE SHP-1 | | Descriptor: | SHP-1 | | Authors: | Yang, J, Liang, X, Niu, T, Meng, W, Zhao, Z, Zhou, G.W. | | Deposit date: | 1998-08-22 | | Release date: | 1999-08-22 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of the catalytic domain of protein-tyrosine phosphatase SHP-1.
J.Biol.Chem., 273, 1998
|
|
5IFG
 | | Crystal structure of HigA-HigB complex from E. Coli | | Descriptor: | Antitoxin HigA, mRNA interferase HigB | | Authors: | Yang, J.S, Zhou, K, Gao, z.Q, Liu, Q.S, Dong, Y.H. | | Deposit date: | 2016-02-26 | | Release date: | 2017-03-01 | | Method: | X-RAY DIFFRACTION (2.702 Å) | | Cite: | Structural insight into the E. coli HigBA complex
Biochem. Biophys. Res. Commun., 478, 2016
|
|
2ASI
 | | ASPARTIC PROTEINASE | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ASPARTIC PROTEINASE, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Yang, J, Jia, Z, Vandonselaar, M, Kepliakov, P.S.A, Quail, J.W. | | Deposit date: | 1995-12-09 | | Release date: | 1996-08-01 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Crystal structure of the aspartic proteinase from Rhizomucor miehei at 2.15 A resolution.
J.Mol.Biol., 268, 1997
|
|
2B3O
 | | Crystal structure of human tyrosine phosphatase SHP-1 | | Descriptor: | Tyrosine-protein phosphatase, non-receptor type 6 | | Authors: | Yang, J, Liu, L, He, D, Song, X, Liang, X, Zhao, Z.J, Zhou, G.W. | | Deposit date: | 2005-09-20 | | Release date: | 2005-10-25 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of human protein-tyrosine phosphatase SHP-1.
J.Biol.Chem., 278, 2003
|
|
8WD0
 | | Crystal structure of T2R-TTL-Erianin complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethyl]phenol, CALCIUM ION, ... | | Authors: | Yang, J. | | Deposit date: | 2023-09-14 | | Release date: | 2024-07-03 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The cytotoxic natural compound erianin binds to colchicine site of beta-tubulin and overcomes taxane resistance
Bioorg.Chem., 150, 2024
|
|
1RDQ
 | | Hydrolysis of ATP in the crystal of Y204A mutant of cAMP-dependent protein kinase | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Yang, J, Ten Eyck, L.F, Xuong, N.H, Taylor, S.S. | | Deposit date: | 2003-11-05 | | Release date: | 2004-04-13 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.26 Å) | | Cite: | Crystal Structure of a cAMP-dependent Protein Kinase Mutant at 1.26A: New Insights into the Catalytic Mechanism.
J.Mol.Biol., 336, 2004
|
|
8XBD
 | |
8XHO
 | |
8XPK
 | |
8XPH
 | | Marine Planctomycetes laminarinase PtLam | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Laminarinase PtLam | | Authors: | Yang, J. | | Deposit date: | 2024-01-03 | | Release date: | 2024-08-28 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Marine Planctomycetes laminarinase PtLam
To Be Published
|
|
8W78
 | | Structure of Drosophila melanogaster L-2-hydroxyglutarate dehydrogenase in complex with FAD and 2-oxoglutarate | | Descriptor: | 2-OXOGLUTARIC ACID, DODECYL-BETA-D-MALTOSIDE, FI05204p, ... | | Authors: | Yang, J, Chen, X, Jin, S, Ding, J. | | Deposit date: | 2023-08-30 | | Release date: | 2023-11-29 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.81 Å) | | Cite: | Structure and biochemical characterization of l-2-hydroxyglutarate dehydrogenase and its role in the pathogenesis of l-2-hydroxyglutaric aciduria.
J.Biol.Chem., 300, 2023
|
|
8W75
 | | Structure of Drosophila melanogaster L-2-hydroxyglutarate dehydrogenase | | Descriptor: | DODECYL-BETA-D-MALTOSIDE, FI05204p, FLAVIN-ADENINE DINUCLEOTIDE | | Authors: | Yang, J, Chen, X, Jin, S, Ding, J. | | Deposit date: | 2023-08-30 | | Release date: | 2023-11-29 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Structure and biochemical characterization of l-2-hydroxyglutarate dehydrogenase and its role in the pathogenesis of l-2-hydroxyglutaric aciduria.
J.Biol.Chem., 300, 2023
|
|
8W7F
 | | Structure of Drosophila melanogaster L-2-hydroxyglutarate dehydrogenase bound with FAD and a sulfate ion | | Descriptor: | DODECYL-BETA-D-MALTOSIDE, FI05204p, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Yang, J, Chen, X, Jin, S, Ding, J. | | Deposit date: | 2023-08-30 | | Release date: | 2023-11-29 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.299 Å) | | Cite: | Structure and biochemical characterization of l-2-hydroxyglutarate dehydrogenase and its role in the pathogenesis of l-2-hydroxyglutaric aciduria.
J.Biol.Chem., 300, 2023
|
|
6JHJ
 | | Structure of Marine bacterial laminarinase mutant-E135A | | Descriptor: | CALCIUM ION, LamCAT | | Authors: | Yang, J, Xu, Y, Miyakawa, T, Tanokura, M, Long, L. | | Deposit date: | 2019-02-18 | | Release date: | 2019-04-03 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Molecular Basis for Substrate Recognition and Catalysis by a Marine Bacterial Laminarinase.
Appl.Environ.Microbiol., 86, 2020
|
|
6JH5
 | | Structure of Marine bacterial laminarinase | | Descriptor: | CALCIUM ION, LamCAT | | Authors: | Yang, J, Xu, Y, Miyakawa, T, Ru, L, Tanokura, M, Long, L. | | Deposit date: | 2019-02-17 | | Release date: | 2019-04-03 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | Molecular Basis for Substrate Recognition and Catalysis by a Marine Bacterial Laminarinase.
Appl.Environ.Microbiol., 86, 2020
|
|
6JIA
 | | Marine bacterial laminarinase mutant E135A complex with laminaritetraose | | Descriptor: | CALCIUM ION, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-alpha-D-glucopyranose, laminarinase | | Authors: | Yang, J, Xu, Y, Miyakawa, T, Tanokura, M, Long, L. | | Deposit date: | 2019-02-20 | | Release date: | 2019-05-15 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Molecular Basis for Substrate Recognition and Catalysis by a Marine Bacterial Laminarinase.
Appl.Environ.Microbiol., 86, 2020
|
|
2KNC
 | | Platelet integrin ALFAIIB-BETA3 transmembrane-cytoplasmic heterocomplex | | Descriptor: | Integrin alpha-IIb, Integrin beta-3 | | Authors: | Yang, J, Ma, Y, Page, R.C, Misra, S, Plow, E.F, Qin, J. | | Deposit date: | 2009-08-20 | | Release date: | 2009-09-29 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Structure of an integrin alphaIIb beta3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation.
Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
1RXT
 | | Crystal structure of human myristoyl-CoA:protein N-myristoyltransferase. | | Descriptor: | COBALT (II) ION, Glycylpeptide N-tetradecanoyltransferase 1, SULFATE ION | | Authors: | Yang, J, Wang, Y, Frey, G, Abeles, R.H, Petsko, G.A, Ringe, D. | | Deposit date: | 2003-12-18 | | Release date: | 2005-04-12 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structure of human myristoyl-CoA:protein N-myristoyltransferase
To be Published
|
|
3QAM
 | | Crystal Structure of Glu208Ala mutant of catalytic subunit of cAMP-dependent protein kinase | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein kinase inhibitor, ... | | Authors: | Yang, J, Wu, J, Steichen, J, Taylor, S.S. | | Deposit date: | 2011-01-11 | | Release date: | 2011-12-07 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | A conserved Glu-Arg salt bridge connects coevolved motifs that define the eukaryotic protein kinase fold.
J.Mol.Biol., 415, 2012
|
|
3PYY
 | | Discovery and Characterization of a Cell-Permeable, Small-molecule c-Abl Kinase Activator that Binds to the Myristoyl Binding Site | | Descriptor: | (5R)-5-[3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]imidazolidine-2,4-dione, 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, GLYCEROL, ... | | Authors: | Yang, J, Campobasso, N, Biju, M.P, Fisher, K, Pan, X.Q, Cottom, J, Galbraith, S, Ho, T, Zhang, H, Hong, X, Ward, P, Hofmann, G, Siegfried, B. | | Deposit date: | 2010-12-13 | | Release date: | 2011-03-09 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Discovery and Characterization of a Cell-Permeable, Small-Molecule c-Abl Kinase Activator that Binds to the Myristoyl Binding Site.
Chem.Biol., 18, 2011
|
|
