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PDB: 352 件
1H6G
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alpha-catenin M-domain
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ALPHA-1 CATENIN, CALCIUM ION, ...
著者Yang, J, Dokurno, P, Tonks, N.K, Barford, D.
登録日2001-06-14
公開日2001-08-07
最終更新日2016-02-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of the M-Fragment of Alpha-Catenin: Implications for Modulation of Cell Adhesion.
Embo J., 20, 2001
8J0P
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Chitin binding SusD-like protein AqSusD from a marine Bacteroidetes
分子名称: Chitin binding SusD-like protein
著者Yang, J.
登録日2023-04-11
公開日2023-11-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural insights of a SusD-like protein in marine Bacteroidetes bacteria reveal the molecular basis for chitin recognition and acquisition.
Febs J., 291, 2024
8JXZ
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Chitin binding SusD-like protein AqSusD in complex with (GlcNAc)3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SusD-like protein AqSusD
著者Yang, J.
登録日2023-07-01
公開日2023-11-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural insights of a SusD-like protein in marine Bacteroidetes bacteria reveal the molecular basis for chitin recognition and acquisition.
Febs J., 291, 2024
1GWZ
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THE PROTEIN TYROSINE PHOSPHATASE SHP-1
分子名称: SHP-1
著者Yang, J, Liang, X, Niu, T, Meng, W, Zhao, Z, Zhou, G.W.
登録日1998-08-22
公開日1999-08-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the catalytic domain of protein-tyrosine phosphatase SHP-1.
J.Biol.Chem., 273, 1998
1F9R
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CRYSTAL STRUCTURE OF PLATELET FACTOR 4 MUTANT 1
分子名称: PLATELET FACTOR 4
著者Yang, J, Doyle, M, Faulk, T, Visentin, G, Aster, R, Edwards, B.
登録日2000-07-11
公開日2003-08-26
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure Comparison of Two Platelet Factor 4 Mutants with the Wild-type Reveals the Epitopes for the Heparin-induced Thrombocytopenia Antibodies
To be Published
1F9Q
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CRYSTAL STRUCTURE OF PLATELET FACTOR 4
分子名称: PLATELET FACTOR 4
著者Yang, J, Doyle, M, Faulk, T, Visentin, G, Aster, R, Edwards, B.
登録日2000-07-11
公開日2003-08-26
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure Comparison of Two Platelet Factor 4 Mutants with the Wild-Type Reveals the Epitopes for the Heparin-Induced Thrombocytopenia Antibodies
To be Published
1FPR
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CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN THE CATALYTIC DOMAIN OF SHP-1 AND AN IN VITRO PEPTIDE SUBSTRATE PY469 DERIVED FROM SHPS-1.
分子名称: PEPTIDE PY469, PROTEIN-TYROSINE PHOSPHATASE 1C
著者Yang, J, Cheng, Z, Niu, Z, Zhao, Z.J, Zhou, G.W.
登録日2000-08-31
公開日2001-03-07
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for substrate specificity of protein-tyrosine phosphatase SHP-1.
J.Biol.Chem., 275, 2000
1F9S
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CRYSTAL STRUCTURE OF PLATELET FACTOR 4 MUTANT 2
分子名称: PLATELET FACTOR 4
著者Yang, J, Doyle, M, Faulk, T, Visentin, G, Aster, R, Edwards, B.
登録日2000-07-11
公開日2003-08-26
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Structure Comparison of Two Platelet Factor 4 Mutants with the Wild-type Reveals the Epitopes for the Heparin-induced Thrombocytopenia Antibodies
To be Published
1F9P
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CRYSTAL STRUCTURE OF CONNECTIVE TISSUE ACTIVATING PEPTIDE-III(CTAP-III) COMPLEXED WITH POLYVINYLSULFONIC ACID
分子名称: CONNECTIVE TISSUE ACTIVATING PEPTIDE-III, ETHANESULFONIC ACID
著者Yang, J, Faulk, T, Aster, R, Visentin, G, Edwards, B, Castor, C.
登録日2000-07-11
公開日2003-08-26
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structure of the CXC Chemokine, Connective Tissue Activating Peptide-III, Complexed with the Heparin Analogue, Polyvinylsulfonic Acid
To be Published
7W1S
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Crystal structure of SARS-CoV-2 spike receptor-binding domain in complex with neutralizing nanobody Nb-007
分子名称: Nanobody Nb-007, Spike protein S1
著者Yang, J, Lin, S, Sun, H.L, Lu, G.W.
登録日2021-11-20
公開日2022-06-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.997 Å)
主引用文献A Potent Neutralizing Nanobody Targeting the Spike Receptor-Binding Domain of SARS-CoV-2 and the Structural Basis of Its Intimate Binding.
Front Immunol, 13, 2022
3PYY
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Discovery and Characterization of a Cell-Permeable, Small-molecule c-Abl Kinase Activator that Binds to the Myristoyl Binding Site
分子名称: (5R)-5-[3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]imidazolidine-2,4-dione, 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, GLYCEROL, ...
著者Yang, J, Campobasso, N, Biju, M.P, Fisher, K, Pan, X.Q, Cottom, J, Galbraith, S, Ho, T, Zhang, H, Hong, X, Ward, P, Hofmann, G, Siegfried, B.
登録日2010-12-13
公開日2011-03-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Discovery and Characterization of a Cell-Permeable, Small-Molecule c-Abl Kinase Activator that Binds to the Myristoyl Binding Site.
Chem.Biol., 18, 2011
3QAM
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Crystal Structure of Glu208Ala mutant of catalytic subunit of cAMP-dependent protein kinase
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein kinase inhibitor, ...
著者Yang, J, Wu, J, Steichen, J, Taylor, S.S.
登録日2011-01-11
公開日2011-12-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献A conserved Glu-Arg salt bridge connects coevolved motifs that define the eukaryotic protein kinase fold.
J.Mol.Biol., 415, 2012
2RMP
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RMP-pepstatin A complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MUCOROPEPSIN, PEPSTATIN, ...
著者Yang, J, Quail, J.W.
登録日1997-05-30
公開日1997-09-17
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of the Rhizomucor miehei aspartic proteinase complexed with the inhibitor pepstatin A at 2.7 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999
1RDQ
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BU of 1rdq by Molmil
Hydrolysis of ATP in the crystal of Y204A mutant of cAMP-dependent protein kinase
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Yang, J, Ten Eyck, L.F, Xuong, N.H, Taylor, S.S.
登録日2003-11-05
公開日2004-04-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Crystal Structure of a cAMP-dependent Protein Kinase Mutant at 1.26A: New Insights into the Catalytic Mechanism.
J.Mol.Biol., 336, 2004
3QAL
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Crystal Structure of Arg280Ala mutant of Catalytic subunit of cAMP-dependent Protein Kinase
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein kinase inhibitor, ...
著者Yang, J, Wu, J, Steichen, J, Taylor, S.S.
登録日2011-01-11
公開日2011-12-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A conserved Glu-Arg salt bridge connects coevolved motifs that define the eukaryotic protein kinase fold.
J.Mol.Biol., 415, 2012
3R4L
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Human very long half life Plasminogen Activator Inhibitor type-1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Plasminogen activator inhibitor 1, beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Yang, J, Zheng, H, Han, Q, Skrzypczak-Jankun, E, Jankun, J.
登録日2011-03-17
公開日2011-11-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Remarkable extension of PAI-1 half-life surprisingly brings no changes to its structure.
Int.J.Mol.Med., 29, 2012
8JJB
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Crystal structure of T2R-TTL-Y61 complex
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ...
著者Yang, J.
登録日2023-05-30
公開日2024-03-27
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Structure-based design and synthesis of BML284 derivatives: A novel class of colchicine-site noncovalent tubulin degradation agents.
Eur.J.Med.Chem., 268, 2024
8JJC
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Tubulin-Y62
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(6,7-dimethoxy-3,4-dihydro-1~{H}-isoquinolin-2-yl)-6-(3-methoxyphenyl)pyrimidin-2-amine, CALCIUM ION, ...
著者Yang, J.
登録日2023-05-30
公開日2024-03-27
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Structure-based design and synthesis of BML284 derivatives: A novel class of colchicine-site noncovalent tubulin degradation agents.
Eur.J.Med.Chem., 268, 2024
8K2O
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Crystal structure of Fhb7-M10
分子名称: Fhb7-M10
著者Yang, J, Lei, X.G, Xiao, J.Y.
登録日2023-07-13
公開日2024-03-13
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Enzymatic Degradation of Deoxynivalenol with the Engineered Detoxification Enzyme Fhb7.
Jacs Au, 4, 2024
8K2P
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Crystal structure of CtGST-F76A
分子名称: Glutathione S-transferase
著者Yang, J, Xiao, J.Y, Lei, X.G.
登録日2023-07-13
公開日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Enzymatic Degradation of Deoxynivalenol with the Engineered Detoxification Enzyme Fhb7.
Jacs Au, 4, 2024
5YOX
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HD domain-containing protein YGK1(YGL101W)
分子名称: HD domain-containing protein YGL101W, ZINC ION
著者Yang, J, Wang, F, Gao, Z, Zhou, K, Liu, Q.
登録日2017-10-31
公開日2018-11-21
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献HD domain-containing protein YGK1(YGL101W)
To Be Published
2ASI
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ASPARTIC PROTEINASE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ASPARTIC PROTEINASE, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Yang, J, Jia, Z, Vandonselaar, M, Kepliakov, P.S.A, Quail, J.W.
登録日1995-12-09
公開日1996-08-01
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of the aspartic proteinase from Rhizomucor miehei at 2.15 A resolution.
J.Mol.Biol., 268, 1997
1O6K
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Structure of activated form of PKB kinase domain S474D with GSK3 peptide and AMP-PNP
分子名称: GLYCOGEN SYNTHASE KINASE-3 BETA, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Yang, J, Cron, P, Good, V.M, Thompson, V, Hemmings, B.A, Barford, D.
登録日2002-10-08
公開日2002-11-19
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of an Activated Akt/Protein Kinase B Ternary Complex with Gsk-3 Peptide and AMP-Pnp
Nat.Struct.Biol., 9, 2002
1O6L
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Crystal structure of an activated Akt/protein kinase B (PKB-PIF chimera) ternary complex with AMP-PNP and GSK3 peptide
分子名称: GLYCOGEN SYNTHASE KINASE-3 BETA, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Yang, J, Cron, P, Good, V.M, Thompson, V, Hemmings, B.A, Barford, D.
登録日2002-10-08
公開日2002-11-19
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of an Activated Akt/Protein Kinase B Ternary Complex with Gsk-3 Peptide and AMP-Pnp
Nat.Struct.Biol., 9, 2002
8JDH
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Crystal structure of anti-CRISPR AcrIF25
分子名称: AcrIF25
著者Yang, J, Wang, J, Wang, Y.
登録日2023-05-14
公開日2024-05-29
最終更新日2024-09-11
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献An anti-CRISPR that pulls apart a CRISPR-Cas complex.
Nature, 632, 2024

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