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PDB: 240 results

7LI7
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BU of 7li7 by Molmil
apo serotonin transporter reconstituted in lipid nanodisc in presence of NaCl in occluded conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, DECANE, ...
Authors:Yang, D, Gouaux, E.
Deposit date:2021-01-26
Release date:2021-12-15
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Illumination of serotonin transporter mechanism and role of the allosteric site.
Sci Adv, 7, 2021
7LIA
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BU of 7lia by Molmil
5-HT bound serotonin transporter reconstituted in lipid nanodisc in presence of NaCl in outward facing conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, CHOLESTEROL, ...
Authors:Yang, D, Gouaux, E.
Deposit date:2021-01-26
Release date:2021-12-15
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Illumination of serotonin transporter mechanism and role of the allosteric site.
Sci Adv, 7, 2021
7LI9
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BU of 7li9 by Molmil
5-HT bound serotonin transporter reconstituted in lipid nanodisc in KCl
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DECANE, ...
Authors:Yang, D, Gouaux, E.
Deposit date:2021-01-26
Release date:2021-12-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Illumination of serotonin transporter mechanism and role of the allosteric site.
Sci Adv, 7, 2021
7LI6
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BU of 7li6 by Molmil
apo SERT reconstituted in lipid nanodisc in KCl
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DECANE, ...
Authors:Yang, D, Gouaux, E.
Deposit date:2021-01-26
Release date:2021-12-15
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Illumination of serotonin transporter mechanism and role of the allosteric site.
Sci Adv, 7, 2021
7LI8
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BU of 7li8 by Molmil
apo serotonin transporter reconstituted in lipid nanodisc in presence of NaCl in inward open conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DECANE, DODECANE, ...
Authors:Yang, D, Gouaux, E.
Deposit date:2021-01-26
Release date:2021-12-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Illumination of serotonin transporter mechanism and role of the allosteric site.
Sci Adv, 7, 2021
8DE4
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BU of 8de4 by Molmil
Native serotonin transporter in complex with 15B8 Fab in the presence of methamphetamine
Descriptor: (2S)-N-methyl-1-phenylpropan-2-amine, 15B8 Fab heavy chain variable domain, 15B8 Fab light chain variable domain, ...
Authors:Yang, D, Gouaux, E.
Deposit date:2022-06-19
Release date:2023-07-05
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Native serotonin transporter in complex with 15B8 Fab in the presence of methamphetamine
To be published
8DE3
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BU of 8de3 by Molmil
Native serotonin transporter in complex with 15B8 Fab antibody in the presence of cocaine
Descriptor: 15B8 Fab heavy chain variable domain, 15B8 Fab light chain variable domain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yang, D, Gouaux, E.
Deposit date:2022-06-19
Release date:2023-07-05
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Native serotonin transporter in complex with 15B8 Fab antibody in the presence of cocaine
To Be Published
7MGW
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BU of 7mgw by Molmil
5-HT bound serotonin transporter reconstituted in lipid nanodisc in NaCl in occluded conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, CHOLESTEROL, ...
Authors:Yang, D, Gouaux, E.
Deposit date:2021-04-13
Release date:2021-12-15
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Illumination of serotonin transporter mechanism and role of the allosteric site.
Sci Adv, 7, 2021
4KUL
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BU of 4kul by Molmil
Crystal structure of N-terminal acetylated yeast Sir3 BAH domain V83P mutant
Descriptor: Regulatory protein SIR3
Authors:Yang, D, Fang, Q, Wang, M, Ren, R, Wang, H, He, M, Sun, Y, Yang, N, Xu, R.M.
Deposit date:2013-05-22
Release date:2013-08-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:N alpha-acetylated Sir3 stabilizes the conformation of a nucleosome-binding loop in the BAH domain.
Nat.Struct.Mol.Biol., 20, 2013
4WGL
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BU of 4wgl by Molmil
Crystal structure of a GroEL D83A/R197A double mutant
Descriptor: 60 kDa chaperonin
Authors:Yang, D, Fei, X, LaRonde, N.A, Beckett, D, Lund, P.A, Lorimer, G.H.
Deposit date:2014-09-19
Release date:2015-09-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:Crystal structure of a GroEL D83A/R197A double mutant
To Be Published
1AU6
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BU of 1au6 by Molmil
SOLUTION STRUCTURE OF DNA D(CATGCATG) INTERSTRAND-CROSSLINKED BY BISPLATIN COMPOUND (1,1/T,T), NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: BIS(TRANS-PLATINUM ETHYLENEDIAMINE DIAMINE CHLORO)COMPLEX, DNA (5'-D(*CP*AP*TP*GP*CP*AP*TP*G)-3')
Authors:Yang, D, Van Boom, S.S.G.E, Reedijk, J, Van Boom, J.H, Farrell, N, Wang, A.H.-J.
Deposit date:1997-09-11
Release date:1998-02-25
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A novel DNA structure induced by the anticancer bisplatinum compound crosslinked to a GpC site in DNA.
Nat.Struct.Biol., 2, 1995
4KUI
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BU of 4kui by Molmil
Crystal structure of N-terminal acetylated yeast Sir3 BAH domain
Descriptor: ACETIC ACID, ISOPROPYL ALCOHOL, Regulatory protein SIR3
Authors:Yang, D, Fang, Q, Wang, M, Ren, R, Wang, H, He, M, Sun, Y, Yang, N, Xu, R.M.
Deposit date:2013-05-22
Release date:2013-08-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:N alpha-acetylated Sir3 stabilizes the conformation of a nucleosome-binding loop in the BAH domain.
Nat.Struct.Mol.Biol., 20, 2013
4KUD
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BU of 4kud by Molmil
Crystal structure of N-terminal acetylated Sir3 BAH domain D205N mutant in complex with yeast nucleosome core particle
Descriptor: Histone H2A.2, Histone H2B.1, Histone H3, ...
Authors:Yang, D, Fang, Q, Wang, M, Ren, R, Wang, H, He, M, Sun, Y, Yang, N, Xu, R.M.
Deposit date:2013-05-22
Release date:2013-08-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.203 Å)
Cite:N alpha-acetylated Sir3 stabilizes the conformation of a nucleosome-binding loop in the BAH domain.
Nat.Struct.Mol.Biol., 20, 2013
1AU5
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BU of 1au5 by Molmil
SOLUTION STRUCTURE OF INTRASTRAND CISPLATIN-CROSSLINKED DNA OCTAMER D(CCTG*G*TCC):D(GGACCAGG), NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: Cisplatin, DNA (5'-D(*CP*CP*TP*GP*GP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*CP*CP*AP*GP*G)-3')
Authors:Yang, D, Van Boom, S.S.G.E, Reedijk, J, Van Boom, J.H, Wang, A.H.-J.
Deposit date:1997-09-11
Release date:1998-02-25
Last modified:2024-04-10
Method:SOLUTION NMR
Cite:Structure and isomerization of an intrastrand cisplatin-cross-linked octamer DNA duplex by NMR analysis.
Biochemistry, 34, 1995
1KKH
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BU of 1kkh by Molmil
Crystal Structure of the Methanococcus jannaschii Mevalonate Kinase
Descriptor: 1,4-DIETHYLENE DIOXIDE, Mevalonate Kinase
Authors:Yang, D, Shipman, L.W, Roessner, C.A, Scott, A.I, Sacchettini, J.C.
Deposit date:2001-12-08
Release date:2002-03-27
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the Methanococcus jannaschii mevalonate kinase, a member of the GHMP kinase superfamily.
J.Biol.Chem., 277, 2002
7LWD
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BU of 7lwd by Molmil
Cryo-EM structure of the wild-type human serotonin transporter complexed with vilazodone, imipramine and 15B8 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE, 5-{4-[4-(5-cyano-1H-indol-3-yl)butyl]piperazin-1-yl}-1-benzofuran-2-carboxamide, ...
Authors:Yang, D, Kalenderoglou, I.E, Gouaux, E, Coleman, J.A, Loland, C.J.
Deposit date:2021-03-01
Release date:2021-08-11
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter.
Nat Commun, 12, 2021
1OPS
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BU of 1ops by Molmil
ICE-BINDING SURFACE ON A TYPE III ANTIFREEZE PROTEIN FROM OCEAN POUT
Descriptor: TYPE III ANTIFREEZE PROTEIN
Authors:Yang, D.S.C, Hon, W.-C, Bubanko, S, Xue, Y, Seetharaman, J, Hew, C.L, Sicheri, F.
Deposit date:1997-11-17
Release date:1998-05-20
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification of the ice-binding surface on a type III antifreeze protein with a "flatness function" algorithm.
Biophys.J., 74, 1998
2M0M
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BU of 2m0m by Molmil
Structural Characterization of Minor Ampullate Spidroin Domains and their Distinct Roles in Fibroin Solubility and Fiber Formation
Descriptor: Minor ampullate fibroin 1
Authors:Yang, D, Gao, Z, Lin, Z, Huang, W, Lai, C, Fan, J.
Deposit date:2012-10-30
Release date:2013-03-27
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural characterization of minor ampullate spidroin domains and their distinct roles in fibroin solubility and fiber formation
Plos One, 8, 2013
2LUU
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BU of 2luu by Molmil
NMR solution structure of midkine-b, mdkb
Descriptor: Midkine-related growth factor Mdk2
Authors:Yang, D, Lim, J, Meng, D.
Deposit date:2012-06-21
Release date:2013-05-01
Last modified:2024-10-09
Method:SOLUTION NMR
Cite:Structure-function analysis of full-length midkine reveals novel residues important for heparin binding and zebrafish embryogenesis.
Biochem.J., 451, 2013
3MHV
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BU of 3mhv by Molmil
Crystal Structure of Vps4 and Vta1
Descriptor: Vacuolar protein sorting-associated protein 4, Vacuolar protein sorting-associated protein VTA1
Authors:Yang, D, Hurley, J.H.
Deposit date:2010-04-09
Release date:2010-10-06
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural role of the Vps4-Vta1 interface in ESCRT-III recycling
Structure, 18, 2010
8WUA
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BU of 8wua by Molmil
cryo-EM structure of human TMEM63A
Descriptor: CSC1-like protein 1
Authors:Yang, D.
Deposit date:2023-10-20
Release date:2024-01-24
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:A monomeric structure of human TMEM63A protein.
Proteins, 92, 2024
2MQA
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BU of 2mqa by Molmil
3D structure of RP domain of MiSp
Descriptor: Minor ampullate fibroin 1
Authors:Yang, D, Gao, Z.
Deposit date:2014-06-16
Release date:2015-06-17
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:3D structure of RP domain of MiSp
To be Published
1WFB
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BU of 1wfb by Molmil
WINTER FLOUNDER ANTIFREEZE PROTEIN ISOFORM HPLC6 AT-180 DEGREES C
Descriptor: ANTIFREEZE PROTEIN ISOFORM HPLC6
Authors:Yang, D.S.C, Sicheri, F.
Deposit date:1995-04-03
Release date:1995-06-03
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Ice-binding structure and mechanism of an antifreeze protein from winter flounder.
Nature, 375, 1995
3EAB
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BU of 3eab by Molmil
Crystal structure of Spastin MIT in complex with ESCRT III
Descriptor: CHMP1b, Spastin
Authors:Yang, D, Rimanchi, N, Renvoise, B, Lippincott-Schwartz, J, Blackstone, C, Hurley, J.H.
Deposit date:2008-08-25
Release date:2008-11-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B.
Nat.Struct.Mol.Biol., 15, 2008
1WFA
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BU of 1wfa by Molmil
WINTER FLOUNDER ANTIFREEZE PROTEIN ISOFORM HPLC6 AT 4 DEGREES C
Descriptor: ANTIFREEZE PROTEIN ISOFORM HPLC6
Authors:Yang, D.S.C, Sicheri, F.
Deposit date:1995-04-03
Release date:1995-06-03
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Ice-binding structure and mechanism of an antifreeze protein from winter flounder.
Nature, 375, 1995

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數據於2024-10-30公開中

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