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3EAB

Crystal structure of Spastin MIT in complex with ESCRT III

Summary for 3EAB
Entry DOI10.2210/pdb3eab/pdb
DescriptorSpastin, CHMP1b (2 entities in total)
Functional Keywordsspastin, chmp, mit, escrt, alternative splicing, atp-binding, cytoplasm, disease mutation, hereditary spastic paraplegia, nucleotide-binding, nucleus, polymorphism, cell cycle
Biological sourceHomo sapiens (Human)
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Cellular locationMembrane; Single-pass membrane protein (Potential): Q9UBP0
Total number of polymer chains12
Total formula weight94415.32
Authors
Yang, D.,Rimanchi, N.,Renvoise, B.,Lippincott-Schwartz, J.,Blackstone, C.,Hurley, J.H. (deposition date: 2008-08-25, release date: 2008-11-11, Last modification date: 2024-02-21)
Primary citationYang, D.,Rismanchi, N.,Renvoise, B.,Lippincott-Schwartz, J.,Blackstone, C.,Hurley, J.H.
Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B.
Nat.Struct.Mol.Biol., 15:1278-1286, 2008
Cited by
PubMed: 18997780
DOI: 10.1038/nsmb.1512
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

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