7MGW

5-HT bound serotonin transporter reconstituted in lipid nanodisc in NaCl in occluded conformation

Summary for 7MGW

• Entry DOI: 10.2210/pdb7mgw/pdb
• EMDB information: 23830
• Descriptor: Sodium-dependent serotonin transporter, SEROTONIN, CHOLESTEROL, ... (11 entities in total)
• Functional Keywords: human serotonin transporter, transport, fab, occluded, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 88130.25

Authors

Yang, D.,Gouaux, E. (deposition date: 2021-04-13, release date: 2021-12-15)

• Primary citation: Yang, D.,Gouaux, E.; Illumination of serotonin transporter mechanism and role of the allosteric site.; Sci Adv, 7:eabl3857-eabl3857, 2021; PubMed: 34851672; DOI: 10.1126/sciadv.abl3857

Experimental method

ELECTRON MICROSCOPY (3.5 Å)