7MGW
5-HT bound serotonin transporter reconstituted in lipid nanodisc in NaCl in occluded conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sodium-dependent serotonin transporter | polymer | 537 | 60677.7 | 1 | UniProt (P31645) Pfam (PF00209) | Homo sapiens (Human) | SERT, 5HT transporter, 5HTT, Solute carrier family 6 member 4 |
| 2 | B (B) | variable domain of 15B8 antibody Fab heavy chain | polymer | 118 | 12980.5 | 1 | Mus musculus (mouse) | ||
| 3 | C (C) | variable domain of 15B8 antiboty Fab light chain | polymer | 110 | 11776.1 | 1 | Mus musculus (mouse) | ||
| 4 | D (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | E (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | F, I, K, L (A) | DODECANE | non-polymer | 170.3 | 4 | Chemie (D12) | |||
| 7 | G (A) | PENTANE | non-polymer | 72.1 | 1 | Chemie (LNK) | |||
| 8 | H, M, N, O, Q... (A) | HEPTANE | non-polymer | 100.2 | 6 | Chemie (HP6) | |||
| 9 | J (A) | DECANE | non-polymer | 142.3 | 1 | Chemie (D10) | |||
| 10 | P, S (A) | SEROTONIN | non-polymer | 176.2 | 2 | Chemie (SRO) | |||
| 11 | T (A) | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 85434.3 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2271.5 | |
| All* | Total formula weight | 88130.3 |
