4DD3
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![BU of 4dd3 by Molmil](/molmil-images/mine/4dd3) | EVAL processed HEWL, carboplatin aqueous paratone | Descriptor: | 2-methylprop-1-ene, CHLORIDE ION, Lysozyme C | Authors: | Tanley, S.W, Schreurs, A.M, Kroon-Batenburg, L.M, Meredith, J, Prendergast, R, Walsh, D, Bryant, P, Levy, C, Helliwell, J.R. | Deposit date: | 2012-01-18 | Release date: | 2012-04-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural studies of the effect that dimethyl sulfoxide (DMSO) has on cisplatin and carboplatin binding to histidine in a protein. Acta Crystallogr.,Sect.D, 68, 2012
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1LKQ
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![BU of 1lkq by Molmil](/molmil-images/mine/1lkq) | NMR STRUCTURE OF HUMAN INSULIN MUTANT ILE-A2-GLY, VAL-A3-GLY, HIS-B10-ASP, PRO-B28-LYS, LYS-B29-PRO, 20 STRUCTURES | Descriptor: | INSULIN | Authors: | Weiss, M.A, Hua, Q.X, Chu, Y.C, Jia, W, Philips, N.F, Wang, R.Y, Katsoyannis, P.G. | Deposit date: | 2002-04-25 | Release date: | 2002-05-22 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | Mechanism of insulin chain combination. Asymmetric roles of A-chain alpha-helices in disulfide pairing J.Biol.Chem., 277, 2002
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4DDB
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![BU of 4ddb by Molmil](/molmil-images/mine/4ddb) | EVAL processed HEWL, cisplatin DMSO paratone pH 6.5 | Descriptor: | Cisplatin, DIMETHYL SULFOXIDE, Lysozyme C | Authors: | Tanley, S.W, Schreurs, A.M, Kroon-Batenburg, L.M, Meredith, J, Prendergast, R, Walsh, D, Bryant, P, Levy, C, Helliwell, J.R. | Deposit date: | 2012-01-18 | Release date: | 2012-04-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural studies of the effect that dimethyl sulfoxide (DMSO) has on cisplatin and carboplatin binding to histidine in a protein. Acta Crystallogr.,Sect.D, 68, 2012
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1JCA
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![BU of 1jca by Molmil](/molmil-images/mine/1jca) | Non-standard Design of Unstable Insulin Analogues with Enhanced Activity | Descriptor: | ZINC ION, insulin a, insulin b | Authors: | Weiss, M.A, Wan, Z, Zhao, M, Chu, Y.-C, Nakagawa, S.H, Burke, G.T, Jia, W, Hellmich, R, Katsoyannis, P.G. | Deposit date: | 2001-06-08 | Release date: | 2001-06-20 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Non-standard insulin design: structure-activity relationships at the periphery of the insulin receptor. J.Mol.Biol., 315, 2002
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1AJZ
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![BU of 1ajz by Molmil](/molmil-images/mine/1ajz) | STRUCTURE OF DIHYDROPTEROATE PYROPHOSPHORYLASE | Descriptor: | DIHYDROPTEROATE SYNTHASE, SULFATE ION | Authors: | Achari, A, Somers, D.O, Champness, J.N, Bryant, P.K, Rosemond, J, Stammers, D.K. | Deposit date: | 1997-05-13 | Release date: | 1998-05-13 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of the anti-bacterial sulfonamide drug target dihydropteroate synthase. Nat.Struct.Biol., 4, 1997
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4R8V
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![BU of 4r8v by Molmil](/molmil-images/mine/4r8v) | Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (wild-type) complex with formate | Descriptor: | 10-formyltetrahydrofolate dehydrogenase, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ... | Authors: | Lin, C.C, Chen, C.J, Fu, T.F, Chuankhayan, P, Kao, T.T, Chang, W.N. | Deposit date: | 2014-09-03 | Release date: | 2015-04-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.197 Å) | Cite: | Structures of the hydrolase domain of zebrafish 10-formyltetrahydrofolate dehydrogenase and its complexes reveal a complete set of key residues for hydrolysis and product inhibition. Acta Crystallogr.,Sect.D, 71, 2015
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3FQ9
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![BU of 3fq9 by Molmil](/molmil-images/mine/3fq9) | Design of an insulin analog with enhanced receptor-binding selectivity. Rationale, structure, and therapeutic implications | Descriptor: | Insulin, ZINC ION | Authors: | Zhao, M, Wan, Z.L, Whittaker, L, Xu, B, Phillips, N, Katsoyannis, P, Whittaker, J, Weiss, M.A. | Deposit date: | 2009-01-07 | Release date: | 2009-08-04 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Design of an insulin analog with enhanced receptor binding selectivity: rationale, structure, and therapeutic implications. J.Biol.Chem., 284, 2009
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6OSM
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![BU of 6osm by Molmil](/molmil-images/mine/6osm) | |
4TT8
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![BU of 4tt8 by Molmil](/molmil-images/mine/4tt8) | Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (wild-type) complex with 10-formyl-5,8-dideazafolate | Descriptor: | 10-formyltetrahydrofolate dehydrogenase, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, N-(4-{[(2-amino-4-hydroxyquinazolin-6-yl)methyl](formyl)amino}benzoyl)-L-glutamic acid | Authors: | Lin, C.C, Chen, C.J, Fu, T.F, Chuankhayan, P, Kao, T.T, Chang, W.N. | Deposit date: | 2014-06-20 | Release date: | 2015-04-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Structures of the hydrolase domain of zebrafish 10-formyltetrahydrofolate dehydrogenase and its complexes reveal a complete set of key residues for hydrolysis and product inhibition. Acta Crystallogr.,Sect.D, 71, 2015
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4QPC
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![BU of 4qpc by Molmil](/molmil-images/mine/4qpc) | Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (Y200A) from zebrafish | Descriptor: | 10-formyltetrahydrofolate dehydrogenase | Authors: | Lin, C.C, Chen, C.J, Fu, T.F, Chuankhayan, P, Kao, T.T, Chang, W.N. | Deposit date: | 2014-06-23 | Release date: | 2015-04-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.902 Å) | Cite: | Structures of the hydrolase domain of zebrafish 10-formyltetrahydrofolate dehydrogenase and its complexes reveal a complete set of key residues for hydrolysis and product inhibition. Acta Crystallogr.,Sect.D, 71, 2015
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5X45
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![BU of 5x45 by Molmil](/molmil-images/mine/5x45) | Crystal structure of 2A protease from Human rhinovirus C15 | Descriptor: | ZINC ION, protease 2A | Authors: | Ling, H, Yang, P, Shaw, N, Sun, Y, Wang, X. | Deposit date: | 2017-02-10 | Release date: | 2018-02-21 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.602 Å) | Cite: | Structural view of the 2A protease from human rhinovirus C15. Acta Crystallogr.,Sect.F, 74, 2018
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4DD0
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![BU of 4dd0 by Molmil](/molmil-images/mine/4dd0) | EVAL processed HEWL, cisplatin aqueous glycerol | Descriptor: | GLYCEROL, Lysozyme C | Authors: | Tanley, S.W, Schreurs, A.M, Kroon-Batenburg, L.M, Meredith, J, Prendergast, R, Walsh, D, Bryant, P, Levy, C, Helliwell, J.R. | Deposit date: | 2012-01-18 | Release date: | 2012-04-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural studies of the effect that dimethyl sulfoxide (DMSO) has on cisplatin and carboplatin binding to histidine in a protein. Acta Crystallogr.,Sect.D, 68, 2012
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6DCG
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![BU of 6dcg by Molmil](/molmil-images/mine/6dcg) | Discovery of MK-8353: An Orally Bioavailable Dual Mechanism ERK Inhibitor for Oncology | Descriptor: | (3S)-3-(methylsulfanyl)-1-(2-{4-[4-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl]-3,6-dihydropyridin-1(2H)-yl}-2-oxoethyl)-N-(3-{6-[(propan-2-yl)oxy]pyridin-3-yl}-1H-indazol-5-yl)pyrrolidine-3-carboxamide, Mitogen-activated protein kinase 1, SULFATE ION | Authors: | Boga, S.B, Deng, Y, Zhu, L, Nan, Y, Cooper, A, Shipps Jr, G.W, Doll, R, Shih, N, Zhu, H, Sun, R, Wang, T, Paliwal, S, Tsui, H, Gao, X, Yao, X, Desai, J, Wang, J, Alhassan, A.B, Kelly, J, Patel, M, Muppalla, K, Gudipati, S, Zhang, L, Buevich, A, Hesk, D, Carr, D, Dayananth, P, Mei, H, Cox, K, Sherborne, B, Hruza, A.W, Xiao, L, Jin, W, Long, B, Liu, G, Taylor, S.A, Kirschmeier, P, Windsor, W.T, Bishop, R, Samatar, A.A. | Deposit date: | 2018-05-06 | Release date: | 2018-08-08 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | MK-8353: Discovery of an Orally Bioavailable Dual Mechanism ERK Inhibitor for Oncology. ACS Med Chem Lett, 9, 2018
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4DDA
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![BU of 4dda by Molmil](/molmil-images/mine/4dda) | EVAL processed HEWL, NAG | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Lysozyme C | Authors: | Tanley, S.W, Schreurs, A.M, Kroon-Batenburg, L.M, Meredith, J, Prendergast, R, Walsh, D, Bryant, P, Levy, C, Helliwell, J.R. | Deposit date: | 2012-01-18 | Release date: | 2012-04-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Structural studies of the effect that dimethyl sulfoxide (DMSO) has on cisplatin and carboplatin binding to histidine in a protein. Acta Crystallogr.,Sect.D, 68, 2012
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4DD1
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![BU of 4dd1 by Molmil](/molmil-images/mine/4dd1) | EVAL processed HEWL, cisplatin aqueous paratone | Descriptor: | 2-methylprop-1-ene, Lysozyme C | Authors: | Tanley, S.W, Schreurs, A.M, Kroon-Batenburg, L.M, Meredith, J, Prendergast, R, Walsh, D, Bryant, P, Levy, C, Helliwell, J.R. | Deposit date: | 2012-01-18 | Release date: | 2012-04-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural studies of the effect that dimethyl sulfoxide (DMSO) has on cisplatin and carboplatin binding to histidine in a protein. Acta Crystallogr.,Sect.D, 68, 2012
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4DD2
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![BU of 4dd2 by Molmil](/molmil-images/mine/4dd2) | EVAL processed HEWL, carboplatin aqueous glycerol | Descriptor: | GLYCEROL, Lysozyme C | Authors: | Tanley, S.W, Schreurs, A.M, Kroon-Batenburg, L.M, Meredith, J, Prendergast, R, Walsh, D, Bryant, P, Levy, C, Helliwell, J.R. | Deposit date: | 2012-01-18 | Release date: | 2012-04-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural studies of the effect that dimethyl sulfoxide (DMSO) has on cisplatin and carboplatin binding to histidine in a protein. Acta Crystallogr.,Sect.D, 68, 2012
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4TTS
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![BU of 4tts by Molmil](/molmil-images/mine/4tts) | Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (Y200A) complex with 10-formyl-5,8-dideazafolate | Descriptor: | 10-formyltetrahydrofolate dehydrogenase, N-(4-{[(2-amino-4-hydroxyquinazolin-6-yl)methyl](formyl)amino}benzoyl)-L-glutamic acid | Authors: | Lin, C.C, Chen, C.J, Fu, T.F, Chuankhayan, P, Kao, T.T, Chang, W.N. | Deposit date: | 2014-06-23 | Release date: | 2015-04-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of the hydrolase domain of zebrafish 10-formyltetrahydrofolate dehydrogenase and its complexes reveal a complete set of key residues for hydrolysis and product inhibition. Acta Crystallogr.,Sect.D, 71, 2015
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4TS4
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![BU of 4ts4 by Molmil](/molmil-images/mine/4ts4) | Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (wild-type) from zebrafish | Descriptor: | 10-formyltetrahydrofolate dehydrogenase | Authors: | Lin, C.C, Chen, C.J, Fu, T.F, Chuankhayan, P, Kao, T.T, Chang, W.N. | Deposit date: | 2014-06-18 | Release date: | 2015-04-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structures of the hydrolase domain of zebrafish 10-formyltetrahydrofolate dehydrogenase and its complexes reveal a complete set of key residues for hydrolysis and product inhibition. Acta Crystallogr.,Sect.D, 71, 2015
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1SJT
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![BU of 1sjt by Molmil](/molmil-images/mine/1sjt) | MINI-PROINSULIN, TWO CHAIN INSULIN ANALOG MUTANT: DES B30, HIS(B 10)ASP, PRO(B 28)ASP, NMR, 20 STRUCTURES | Descriptor: | PROINSULIN | Authors: | Hua, Q.X, Hu, S.Q, Jia, W.H, Chu, Y.C, Burke, G.T, Wang, S.H, Katsoyannis, P.G, Weiss, M.A. | Deposit date: | 1997-10-09 | Release date: | 1998-03-18 | Last modified: | 2021-11-03 | Method: | SOLUTION NMR | Cite: | Mini-proinsulin and mini-IGF-I: homologous protein sequences encoding non-homologous structures. J.Mol.Biol., 277, 1998
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5YL0
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![BU of 5yl0 by Molmil](/molmil-images/mine/5yl0) | The crystal structure of Penaeus vannamei nodavirus P-domain (P212121) | Descriptor: | Capsid protein | Authors: | Chen, N.C, Yoshimura, M, Lin, C.C, Guan, H.H, Chuankhayan, P, Chen, C.J. | Deposit date: | 2017-10-16 | Release date: | 2018-10-24 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.22 Å) | Cite: | The atomic structures of shrimp nodaviruses reveal new dimeric spike structures and particle polymorphism. Commun Biol, 2, 2019
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5YKX
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![BU of 5ykx by Molmil](/molmil-images/mine/5ykx) | The crystal structure of Macrobrachium rosenbergii nodavirus P-domain with Cd ion | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CADMIUM ION, Capsid protein, ... | Authors: | Chen, N.C, Yoshimura, M, Lin, C.C, Guan, H.H, Chuankhayan, P, Chen, C.J. | Deposit date: | 2017-10-16 | Release date: | 2018-10-24 | Last modified: | 2019-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The atomic structures of shrimp nodaviruses reveal new dimeric spike structures and particle polymorphism. Commun Biol, 2, 2019
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5YKZ
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![BU of 5ykz by Molmil](/molmil-images/mine/5ykz) | The crystal structure of Penaeus vannamei nodavirus P-domain (P21) | Descriptor: | Capsid protein | Authors: | Chen, N.C, Yoshimura, M, Lin, C.C, Guan, H.H, Chuankhayan, P, Chen, C.J. | Deposit date: | 2017-10-16 | Release date: | 2018-10-24 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.17 Å) | Cite: | The atomic structures of shrimp nodaviruses reveal new dimeric spike structures and particle polymorphism. Commun Biol, 2, 2019
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5YKV
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![BU of 5ykv by Molmil](/molmil-images/mine/5ykv) | The crystal structure of Macrobrachium rosenbergii nodavirus P-domain | Descriptor: | Capsid protein | Authors: | Chen, N.C, Yoshimura, M, Lin, C.C, Guan, H.H, Chuankhayan, P, Chen, C.J. | Deposit date: | 2017-10-16 | Release date: | 2018-10-24 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | The atomic structures of shrimp nodaviruses reveal new dimeric spike structures and particle polymorphism. Commun Biol, 2, 2019
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5YKU
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![BU of 5yku by Molmil](/molmil-images/mine/5yku) | The crystal structure of Macrobrachium rosenbergii nodavirus P-domain with Zn ions | Descriptor: | Capsid protein, ZINC ION | Authors: | Chen, N.C, Yoshimura, M, Lin, C.C, Guan, H.H, Chuankhayan, P, Chen, C.J. | Deposit date: | 2017-10-16 | Release date: | 2018-10-24 | Last modified: | 2019-03-13 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | The atomic structures of shrimp nodaviruses reveal new dimeric spike structures and particle polymorphism. Commun Biol, 2, 2019
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1KN6
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![BU of 1kn6 by Molmil](/molmil-images/mine/1kn6) | |