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PDB: 310 件

2D0K
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Methionine-free mutant of Escherichia coli dihydrofolate reductase
分子名称: CHLORIDE ION, Dihydrofolate reductase, FOLIC ACID
著者Katayanagi, K.
登録日2005-08-04
公開日2006-02-28
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Evolutional Design of a Hyperactive Cysteine- and Methionine-free Mutant of Escherichia coli Dihydrofolate Reductase
J.Biol.Chem., 281, 2006
1RDA
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CRYSTAL STRUCTURES OF RIBONUCLEASE HI ACTIVE SITE MUTANTS FROM ESCHERICHIA COLI
分子名称: RIBONUCLEASE H
著者Katayanagi, K, Morikawa, K.
登録日1993-06-23
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structures of ribonuclease HI active site mutants from Escherichia coli.
J.Biol.Chem., 268, 1993
1FUT
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CRYSTAL STRUCTURES OF RIBONUCLEASE F1 OF FUSARIUM MONILIFORME IN ITS FREE FORM AND IN COMPLEX WITH 2'GMP
分子名称: GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE F1
著者Katayanagi, K, Vassylyev, D.G, Ishikawa, K, Morikawa, K.
登録日1993-01-18
公開日1993-10-31
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of ribonuclease F1 of Fusarium moniliforme in its free form and in complex with 2'GMP.
J.Mol.Biol., 230, 1993
1FUS
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CRYSTAL STRUCTURES OF RIBONUCLEASE F1 OF FUSARIUM MONILIFORME IN ITS FREE FORM AND IN COMPLEX WITH 2'GMP
分子名称: RIBONUCLEASE F1
著者Katayanagi, K, Vassylyev, D.G, Ishikawa, K, Morikawa, K.
登録日1993-01-18
公開日1993-10-31
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal structures of ribonuclease F1 of Fusarium moniliforme in its free form and in complex with 2'GMP.
J.Mol.Biol., 230, 1993
2A2Y
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NMR Structue of Sso10b2 from Sulfolobus solfataricus
分子名称: DNA/RNA-binding protein Alba 2
著者Biyani, K, Kahsai, M.A, Clark, A.T, Armstrong, T.L, Edmondson, S.P, Shriver, J.W.
登録日2005-06-23
公開日2005-11-08
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure, stability, and nucleic Acid binding of the hyperthermophile protein sso10b2.
Biochemistry, 44, 2005
7OYL
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Phosphoglucose isomerase of Aspergillus fumigatus in complexed with Glucose-6-phosphate
分子名称: 6-O-phosphono-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ...
著者Raimi, O.G, Yan, K, Fang, W, van Aalten, D.M.F.
登録日2021-06-24
公開日2022-07-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Phosphoglucose Isomerase Is Important for Aspergillus fumigatus Cell Wall Biogenesis.
Mbio, 13, 2022
7P5O
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Crystal structure of Aspergillus fumigatus phosphoglucomutase in complex with the reaction intermediate
分子名称: 1,6-di-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, Phosphoglucomutase
著者Raimi, O.G, Yan, K, van Aalten, D.M.F.
登録日2021-07-14
公開日2022-07-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Targeting an essential step in the biosynthetic pathway of uridine diphosphate glucose in Aspergillus fumigatus
To Be Published
1N3H
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Coupling of Folding and Binding in the PTB Domain of the Signaling Protein Shc
分子名称: SHC Transforming protein
著者Farooq, A, Zeng, L, Yan, K.S, Ravichandran, K.S, Zhou, M.-M.
登録日2002-10-28
公開日2003-10-28
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Coupling of Folding and Binding in the PTB Domain of the Signaling Protein Shc
Structure, 11, 2003
1OY2
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Coupling of Folding and Binding in the PTB Domain of the Signaling Protein Shc
分子名称: SHC transforming protein
著者Farooq, A, Zeng, L, Yan, K.S, Ravichandran, K.S, Zhou, M.-M.
登録日2003-04-03
公開日2004-04-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Coupling of Folding and Binding in the PTB Domain of the Signaling Protein Shc
Structure, 11, 2003
7PPR
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The structure of UDP-glucose pyrophosphorylase from Aspergillus fumigatus
分子名称: CHLORIDE ION, SULFATE ION, UTP--glucose-1-phosphate uridylyltransferase
著者Morton, S, Raimi, O.G, Yan, K, van Aalten, D.M.F.
登録日2021-09-14
公開日2022-09-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Genetic and structural validation of UDP-glucose pyrophosphorylase as a novel antifungal target against Aspergillus fumigatus
To Be Published
3J8G
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Electron cryo-microscopy structure of EngA bound with the 50S ribosomal subunit
分子名称: 23S rRNA, 50S ribosomal protein L1, 50S ribosomal protein L11, ...
著者Zhang, X, Yan, K, Zhang, Y, Li, N, Ma, C, Li, Z, Zhang, Y, Feng, B, Liu, J, Sun, Y, Xu, Y, Lei, J, Gao, N.
登録日2014-10-24
公開日2014-11-26
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Structural insights into the function of a unique tandem GTPase EngA in bacterial ribosome assembly
Nucleic Acids Res., 2014
3JCE
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Structure of Escherichia coli EF4 in pretranslocational ribosomes (Pre EF4)
分子名称: 16S ribosomal RNA, 23 ribosomal RNA, 30S ribosomal protein S10, ...
著者Zhang, D, Yan, K, Liu, G, Song, G, Luo, J, Shi, Y, Cheng, E, Wu, S, Jiang, T, Low, J, Gao, N, Qin, Y.
登録日2015-12-01
公開日2016-01-13
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献EF4 disengages the peptidyl-tRNA CCA end and facilitates back-translocation on the 70S ribosome
Nat. Struct. Mol. Biol., 23, 2016
3JCD
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Structure of Escherichia coli EF4 in posttranslocational ribosomes (Post EF4)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Zhang, D, Yan, K, Liu, G, Song, G, Luo, J, Shi, Y, Cheng, E, Wu, S, Jiang, T, Low, J, Gao, N, Qin, Y.
登録日2015-12-01
公開日2016-01-13
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献EF4 disengages the peptidyl-tRNA CCA end and facilitates back-translocation on the 70S ribosome
Nat. Struct. Mol. Biol., 23, 2016
5H4P
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Structural snapshot of cytoplasmic pre-60S ribosomal particles bound with Nmd3, Lsg1, Tif6 and Reh1
分子名称: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
著者Ma, C, Wu, S, Li, N, Chen, Y, Yan, K, Li, Z, Zheng, L, Lei, J, Woolford, J.L, Gao, N.
登録日2016-11-01
公開日2017-01-25
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Structural snapshot of cytoplasmic pre-60S ribosomal particles bound by Nmd3, Lsg1, Tif6 and Reh1
Nat. Struct. Mol. Biol., 24, 2017
1XR0
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BU of 1xr0 by Molmil
Structural Basis of SNT PTB Domain Interactions with Distinct Neurotrophic Receptors
分子名称: Basic fibroblast growth factor receptor 1, FGFR signalling adaptor SNT-1
著者Dhalluin, C, Yan, K.S, Plotnikova, O, Lee, K.W, Zeng, L, Kuti, M, Mujtaba, S, Goldfarb, M.P, Zhou, M.-M.
登録日2004-10-13
公開日2004-11-02
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural Basis of SNT PTB Domain Interactions with Distinct Neurotrophic Receptors
Mol.Cell, 6, 2000
8QH2
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Crystal structure of chimeric UAP1L1
分子名称: UDP-N-acetylhexosamine pyrophosphorylase,UDP-N-acetylhexosamine pyrophosphorylase-like protein 1
著者Chen, X, Yan, K, Bartual, S, van Aalten, D.
登録日2023-09-06
公開日2024-09-18
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献UAP1L1 is an active pyrophosphorylase with an active site disulfide regulating protein thermostability
To Be Published
2L5C
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Solution structures of human PIWI-like 1 PAZ domain
分子名称: Piwi-like protein 1
著者Zeng, L, Zhang, Q, Yan, K, Zhou, M.
登録日2010-10-29
公開日2011-04-20
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural insights into piRNA recognition by the human PIWI-like 1 PAZ domain.
Proteins, 79, 2011
2L5D
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Solution Structures of human PIWI-like 1 PAZ domain with ssRNA (5'-pUGACA)
分子名称: 5'-R(*UP*GP*AP*CP*A)-3', Piwi-like protein 1
著者Zeng, L, Zhang, Q, Yan, K, Zhou, M.
登録日2010-10-29
公開日2011-04-20
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural insights into piRNA recognition by the human PIWI-like 1 PAZ domain.
Proteins, 79, 2011
5JMC
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Receptor binding domain of Botulinum neurotoxin A in complex with rat SV2C
分子名称: Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2C
著者Yao, G, Zhang, S, Mahrhold, S, Lam, K, Stern, D, Bagramyan, K, Perry, K, Kalkum, M, Rummel, A, Dong, M, Jin, R.
登録日2016-04-28
公開日2016-06-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
Nat.Struct.Mol.Biol., 23, 2016
1KVB
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BU of 1kvb by Molmil
E. COLI RIBONUCLEASE HI D134H MUTANT
分子名称: RIBONUCLEASE H
著者Kashiwagi, T, Jeanteur, D, Haruki, M, Katayanagi, K, Kanaya, S, Morikawa, K.
登録日1996-10-04
公開日1997-03-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Proposal for new catalytic roles for two invariant residues in Escherichia coli ribonuclease HI.
Protein Eng., 9, 1996
4MRO
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BU of 4mro by Molmil
Human GKRP bound to AMG-5980 and S6P
分子名称: 2-(4-{4-[(6-aminopyridin-3-yl)sulfonyl]piperazin-1-yl}phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol, D-SORBITOL-6-PHOSPHATE, GLYCEROL, ...
著者St Jean, D.J, Ashton, K.S, Bartberger, M.D, Chen, J, Chmait, S, Cupples, R, Galbreath, E, Helmering, J, Jordan, S.R, Liu, L, Kunz, K, Michelsen, K, Nishimura, N, Pennington, L.D, Poon, S.F, Sivits, G, Stec, M.M, Tamayo, N, Van, G, Yang, K, Norman, M.H, Fotsch, C, LLoyd, D.J, Hale, C.
登録日2013-09-17
公開日2014-05-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 2. Leveraging structure-based drug design to identify analogues with improved pharmacokinetic profiles.
J.Med.Chem., 57, 2014
2HKO
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Crystal structure of LSD1
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1
著者Chen, Y, Yang, Y.T, Wang, F, Yanane, K, Zhang, Y, Lei, M.
登録日2006-07-05
公開日2006-08-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of human histone lysine-specific demethylase 1 (LSD1).
Proc.Natl.Acad.Sci.Usa, 103, 2006
5X8Y
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A Mutation identified in Neonatal Microcephaly Destabilizes Zika Virus NS1 Assembly in vitro
分子名称: ZIKV NS1
著者Wang, D, Chen, C, Liu, S, Zhou, H, Yang, K, Zhao, Q, Ji, X, Chen, C, Xie, W, Wang, Z, Mi, L.Z, Yang, H.
登録日2017-03-03
公開日2017-05-17
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.817 Å)
主引用文献A Mutation Identified in Neonatal Microcephaly Destabilizes Zika Virus NS1 Assembly in Vitro
Sci Rep, 7, 2017
7LMC
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Structure of SARS CoV-2 main protease shows simultaneous processing of its N- and C-terminii
分子名称: 3C-like proteinase, Non-structural protein 4 peptide
著者Gajiwala, K.S, Ferre, R.A, Liu, W, Ryan, K.
登録日2021-02-05
公開日2021-04-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.977 Å)
主引用文献SARS coronavirus-2 main protease dimer auto-processes N-terminus in cis and C-terminus in trans
To Be Published
1RKU
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Crystal Structure of ThrH gene product of Pseudomonas Aeruginosa
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, homoserine kinase
著者Singh, S.K, Yang, K, Subramanian, K, Karthikeyan, S, Huynh, T, Zhang, X, Phillips, M.A, Zhang, H.
登録日2003-11-23
公開日2004-03-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献The thrH Gene Product of Pseudomonas aeruginosa Is a Dual Activity Enzyme with a Novel Phosphoserine:Homoserine Phosphotransferase Activity.
J.Biol.Chem., 279, 2004

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