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7PPR

The structure of UDP-glucose pyrophosphorylase from Aspergillus fumigatus

Summary for 7PPR
Entry DOI10.2210/pdb7ppr/pdb
DescriptorUTP--glucose-1-phosphate uridylyltransferase, SULFATE ION, CHLORIDE ION, ... (4 entities in total)
Functional Keywordsugp, udp-glucose pyrophosphorylase, transferase
Biological sourceNeosartorya fumigata (Aspergillus fumigatus)
Total number of polymer chains2
Total formula weight111264.81
Authors
Morton, S.,Raimi, O.G.,Yan, K.,van Aalten, D.M.F. (deposition date: 2021-09-14, release date: 2022-09-21, Last modification date: 2024-01-31)
Primary citationYan, K.,Raimi, O.G.,Morton, S.,Ferenbach, A.T.,Wei, P.,Yuan, H.,Fang, W.,van Aalten, D.M.F.
Genetic and structural validation of UDP-glucose pyrophosphorylase as a novel antifungal target against Aspergillus fumigatus
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.57 Å)
Structure validation

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