7C8I
 
 | | Ambient temperature structure of Bifidobacgterium longum phosphoketolase with thiamine diphosphate and phosphoenol pyuruvate | | Descriptor: | CALCIUM ION, PHOSPHOENOLPYRUVATE, THIAMINE DIPHOSPHATE, ... | | Authors: | Nakata, K, Kashiwagi, T, Nango, E, Miyano, H, Mizukoshi, T, Iwata, S. | | Deposit date: | 2020-06-01 | | Release date: | 2021-06-02 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Ambient temperature structure of phosphoketolase from Bifidobacterium longum determined by serial femtosecond X-ray crystallography.
Acta Crystallogr D Struct Biol, 79, 2023
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7VBA
 | | Structure of the pre state human RNA Polymerase I Elongation Complex | | Descriptor: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (5'-D(P*A*CP*TP*GP*TP*CP*CP*TP*CP*TP*GP*GP*C)-3'), DNA (5'-D(P*GP*CP*CP*AP*GP*AP*GP*AP*CP*AP*GP*CP*GP*AP*GP*TP*CP*AP*GP*CP*AP*A)-3'), ... | | Authors: | Zhao, D, Liu, W, Chen, K, Yang, H, Xu, Y. | | Deposit date: | 2021-08-31 | | Release date: | 2022-02-16 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (2.89 Å) | | Cite: | Structure of the human RNA polymerase I elongation complex.
Cell Discov, 7, 2021
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7VBC
 | | Back track state of human RNA Polymerase I Elongation Complex | | Descriptor: | DNA (5'-D(*GP*TP*AP*CP*TP*GP*TP*CP*CP*TP*CP*TP*GP*G)-3'), DNA (5'-D(P*AP*GP*GP*AP*CP*AP*GP*CP*GP*TP*GP*TP*CP*AP*GP*CP*AP*AP*TP*A)-3'), DNA-directed RNA polymerase I subunit RPA1, ... | | Authors: | Zhao, D, Liu, W, Chen, K, Yang, H, Xu, Y. | | Deposit date: | 2021-08-31 | | Release date: | 2022-02-16 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.01 Å) | | Cite: | Structure of the human RNA polymerase I elongation complex.
Cell Discov, 7, 2021
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7VBB
 | | Structure of the post state human RNA Polymerase I Elongation Complex | | Descriptor: | DNA (25-MER), DNA (5'-D(*CP*TP*GP*TP*CP*CP*TP*CP*TP*GP*GP*CP*GP*A)-3'), DNA-directed RNA polymerase I subunit RPA1, ... | | Authors: | Zhao, D, Liu, W, Chen, K, Yang, H, Xu, Y. | | Deposit date: | 2021-08-31 | | Release date: | 2022-03-02 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (2.81 Å) | | Cite: | Structure of the human RNA polymerase I elongation complex.
Cell Discov, 7, 2021
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6JIV
 | | SspE crystal structure | | Descriptor: | SspE protein | | Authors: | Bing, Y.Z, Yang, H.G. | | Deposit date: | 2019-02-23 | | Release date: | 2020-03-25 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (3.31 Å) | | Cite: | SspABCD-SspE is a phosphorothioation-sensing bacterial defence system with broad anti-phage activities.
Nat Microbiol, 5, 2020
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3VIU
 | | Crystal structure of PurL from thermus thermophilus | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | | Authors: | Suzuki, S, Yanai, H, Kanagawa, M, Tamura, S, Watanabe, Y, Fuse, K, Baba, S, Sampei, G, Kawai, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2011-10-12 | | Release date: | 2012-01-18 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structure of N-formylglycinamide ribonucleotide amidotransferase II (PurL) from Thermus thermophilus HB8
Acta Crystallogr.,Sect.F, 68, 2012
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7WMK
 | | PQQ-dependent alcohol dehydrogenase complexed with PQQ | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, CALCIUM ION, ... | | Authors: | Chen, M, Yang, H, Lv, F. | | Deposit date: | 2022-01-15 | | Release date: | 2022-09-07 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.47 Å) | | Cite: | Structure-Function Analysis of a Quinone-Dependent Dehydrogenase Capable of Deoxynivalenol Detoxification.
J.Agric.Food Chem., 70, 2022
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7XXE
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4HPW
 | | Crystal structure of Tyrosine-tRNA ligase mutant complexed with unnatural amino acid 3-o-methyl-Tyrosine | | Descriptor: | 3-methoxy-L-tyrosine, Tyrosine--tRNA ligase | | Authors: | Yu, Y, Zhou, Q, Dong, J, Li, J, Xiaoxuan, L, Mukherjee, A, Ouyang, H, Nilges, M, Li, H, Gao, F, Gong, W, Lu, Y, Wang, J. | | Deposit date: | 2012-10-24 | | Release date: | 2013-10-30 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.998 Å) | | Cite: | Crystal structure of Tyrosine-tRNA ligase mutant complexed with unnatural amino acid 3-o-methyl-Tyrosine
To be Published
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4HK4
 | | Crystal structure of apo Tyrosine-tRNA ligase mutant protein | | Descriptor: | DI(HYDROXYETHYL)ETHER, Tyrosine--tRNA ligase | | Authors: | Yu, Y, Zhou, Q, Dong, J, Li, J, Xiaoxuan, L, Mukherjee, A, Ouyang, H, Nilges, M, Li, H, Gao, F, Gong, W, Lu, Y, Wang, J. | | Deposit date: | 2012-10-15 | | Release date: | 2013-04-17 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.298 Å) | | Cite: | Crystal structure of apo Tyrosine-tRNA ligase mutant protein
To be Published
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8U8H
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8U95
 | | The structure of myosin heavy chain from Drosophila melanogaster flight muscle thick filaments | | Descriptor: | Myosin heavy chain, isoform U | | Authors: | Abbasi Yeganeh, F, Rastegarpouyani, H, Li, J, Taylor, K.A. | | Deposit date: | 2023-09-18 | | Release date: | 2023-10-18 | | Last modified: | 2023-11-01 | | Method: | ELECTRON MICROSCOPY (4.7 Å) | | Cite: | Structure of the Drosophila melanogaster Flight Muscle Myosin Filament at 4.7 angstrom Resolution Reveals New Details of Non-Myosin Proteins.
Int J Mol Sci, 24, 2023
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7ERV
 | | Crystal structure of L-histidine decarboxylase (C57S/C101V/C282V mutant) from Photobacterium phosphoreum | | Descriptor: | Histidine decarboxylase, IMIDAZOLE | | Authors: | Oda, Y, Nakata, K, Yamaguchi, H, Kashiwagi, T, Miyano, H, Mizukoshi, T. | | Deposit date: | 2021-05-07 | | Release date: | 2022-02-16 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural insights into the enhanced thermostability of cysteine substitution mutants of L-histidine decarboxylase from Photobacterium phosphoreum.
J.Biochem., 171, 2022
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7ERU
 | | Crystal structure of L-histidine decarboxylase (C57S mutant) from Photobacterium phosphoreum | | Descriptor: | Histidine decarboxylase | | Authors: | Oda, Y, Nakata, K, Yamaguchi, H, Kashiwagi, T, Miyano, H, Mizukoshi, T. | | Deposit date: | 2021-05-07 | | Release date: | 2022-02-16 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Structural insights into the enhanced thermostability of cysteine substitution mutants of L-histidine decarboxylase from Photobacterium phosphoreum.
J.Biochem., 171, 2022
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7WMD
 | | PQQ-dependent alcohol dehydrogenase detoxifying DON | | Descriptor: | CALCIUM ION, PQQ-dependent alcohol dehydrogenase | | Authors: | Chen, M, Yang, H, Lv, F. | | Deposit date: | 2022-01-14 | | Release date: | 2022-09-07 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure-Function Analysis of a Quinone-Dependent Dehydrogenase Capable of Deoxynivalenol Detoxification.
J.Agric.Food Chem., 70, 2022
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7W33
 | | The crystal structure of human CtsL in complex with 14a | | Descriptor: | N-[(2S)-3-(4-fluorophenyl)-1-oxidanylidene-1-[[(2R,3S)-3-oxidanyl-4-oxidanylidene-1-[(3S)-2-oxidanylidenepiperidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]amino]propan-2-yl]-1-benzofuran-2-carboxamide, Procathepsin L | | Authors: | Zhao, Y, Shao, M, Zhao, J, Yang, H, Rao, Z. | | Deposit date: | 2021-11-25 | | Release date: | 2023-05-31 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.39 Å) | | Cite: | Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1.
Signal Transduct Target Ther, 9, 2024
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7W34
 | | The crystal structure of human CtsL in complex with 14b | | Descriptor: | N-[(2S)-3-cyclohexyl-1-oxidanylidene-1-[[(2S,3S)-3-oxidanyl-4-oxidanylidene-1-[(3S)-2-oxidanylidenepiperidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]amino]propan-2-yl]-1-benzofuran-2-carboxamide, Procathepsin L | | Authors: | Zhao, Y, Shao, M, Zhao, J, Yang, H, Rao, Z. | | Deposit date: | 2021-11-25 | | Release date: | 2023-05-31 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.89 Å) | | Cite: | Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1.
Signal Transduct Target Ther, 9, 2024
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7VMU
 | | Crystal Structure of SARS-CoV Spike Receptor-Binding Domain Complexed with Neutralizing Antibody | | Descriptor: | Spike protein S1, scFv E4 | | Authors: | Guo, Y, Wang, W, Jiao, P, Yang, H, Rao, Z, Cheng, G. | | Deposit date: | 2021-10-09 | | Release date: | 2021-11-03 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.89 Å) | | Cite: | Antibody engineering improves neutralization activity against K417 spike mutant SARS-CoV-2 variants.
Cell Biosci, 12, 2022
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2IP4
 | | Crystal Structure of Glycinamide Ribonucleotide Synthetase from Thermus thermophilus HB8 | | Descriptor: | Phosphoribosylamine--glycine ligase, SULFATE ION | | Authors: | Sampei, G, Baba, S, Kanagawa, M, Yanai, H, Ishii, T, Kawai, H, Fukai, Y, Ebihara, A, Nakagawa, N, Kawai, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-10-11 | | Release date: | 2007-10-30 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structures of glycinamide ribonucleotide synthetase, PurD, from thermophilic eubacteria
J.Biochem., 148, 2010
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6KLL
 | | F-actin of cardiac thin filament in low-calcium state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Oda, T, Yanagisawa, H, Wakabayashi, T. | | Deposit date: | 2019-07-30 | | Release date: | 2020-01-15 | | Last modified: | 2020-03-11 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Cryo-EM structures of cardiac thin filaments reveal the 3D architecture of troponin.
J.Struct.Biol., 209, 2020
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6KLN
 | | F-actin of cardiac thin filament in high-calcium state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Oda, T, Yanagisawa, H, Wakabayashi, T. | | Deposit date: | 2019-07-30 | | Release date: | 2020-01-15 | | Last modified: | 2020-03-11 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Cryo-EM structures of cardiac thin filaments reveal the 3D architecture of troponin.
J.Struct.Biol., 209, 2020
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7W7O
 | | The crystal structure of human Calpain-1 protease core in complex with 14a | | Descriptor: | CALCIUM ION, Calpain-1 catalytic subunit, HYDROSULFURIC ACID, ... | | Authors: | Zhao, Y, Zhao, J, Shao, M, Yang, H, Rao, Z. | | Deposit date: | 2021-12-06 | | Release date: | 2023-06-07 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.59 Å) | | Cite: | The crystal structure of human Calpain-1 protease core in complex with 14a
To Be Published
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2AYR
 | | A SERM Designed for the Treatment of Uterine Leiomyoma with Unique Tissue Specificity for Uterus and Ovaries in Rats | | Descriptor: | 6-(4-METHYLSULFONYL-PHENYL)-5-[4-(2-PIPERIDIN-1-YLETHOXY)PHENOXY]NAPHTHALEN-2-OL, Estrogen receptor | | Authors: | Hummel, C.W, Geiser, A.G, Bryant, H.U, Cohen, I.R, Dally, R.D, Fong, K.C, Frank, S.A, Hinklin, R, Jones, S.A, Lewis, G, McCann, D.J, Shepherd, T.A, Tian, H, Rudman, D.G, Wallace, O.B, Wang, Y, Dodge, J.A. | | Deposit date: | 2005-09-07 | | Release date: | 2005-11-22 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A selective estrogen receptor modulator designed for the treatment of uterine leiomyoma with unique tissue specificity for uterus and ovaries in rats
J.Med.Chem., 48, 2005
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2K28
 | | Solution NMR structure of the chromo domain of the chromobox protein homolog 4 | | Descriptor: | E3 SUMO-protein ligase CBX4 | | Authors: | Kaustov, L, Lemak, A, Quyang, H, Fares, C, Gutmanas, A, Ravichandran, M, Loppnau, P, Bountra, C, Weigelt, J, Edwards, A.M, Min, J, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | | Deposit date: | 2008-03-27 | | Release date: | 2008-04-08 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of the chromo domain of the chromobox protein homolog 4.
To be Published
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2K1B
 | | Solution NMR structure of the chromo domain of the chromobox protein homolog 7 | | Descriptor: | Chromobox protein homolog 7 | | Authors: | Kaustov, L, Lemak, A, Quyang, H, Gutmanas, A, Fares, C, Bountra, C, Weigelt, J, Loppnau, P, Ravichandran, M, Edwards, A.M, Min, J, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | | Deposit date: | 2008-02-25 | | Release date: | 2008-03-11 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of the chromobox protein homolog 7.
To be Published
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