7W7O

The crystal structure of human Calpain-1 protease core in complex with 14a

Summary for 7W7O

• Entry DOI: 10.2210/pdb7w7o/pdb
• Descriptor: Calpain-1 catalytic subunit, N-[(2S)-3-(4-fluorophenyl)-1-oxidanylidene-1-[[(2S,3S)-3-oxidanyl-4-oxidanylidene-1-[(3S)-2-oxidanylidenepiperidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]amino]propan-2-yl]-1-benzofuran-2-carboxamide, HYDROSULFURIC ACID, ... (5 entities in total)
• Functional Keywords: human protease, calpain-1, antiviral inhibitor, 14a, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 38444.36

Authors

Zhao, Y.,Zhao, J.,Shao, M.,Yang, H.,Rao, Z. (deposition date: 2021-12-06, release date: 2023-06-07, Last modification date: 2023-11-29)

• Primary citation: Zhao, Y.,Zhao, J.,Shao, M.,Yang, H.,Rao, Z.; The crystal structure of human Calpain-1 protease core in complex with 14a; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.59 Å)