Summary for 3VIU
| Entry DOI | 10.2210/pdb3viu/pdb |
| Descriptor | Phosphoribosylformylglycinamidine synthase 2, ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, ... (6 entities in total) |
| Functional Keywords | structural genomics, riken structural genomics/proteomics initiative, rsgi, ligase, purine metabolism, atp-binding |
| Biological source | Thermus thermophilus |
| Cellular location | Cytoplasm (By similarity): Q5SMH8 |
| Total number of polymer chains | 1 |
| Total formula weight | 80003.41 |
| Authors | Suzuki, S.,Yanai, H.,Kanagawa, M.,Tamura, S.,Watanabe, Y.,Fuse, K.,Baba, S.,Sampei, G.,Kawai, G.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2011-10-12, release date: 2012-01-18, Last modification date: 2024-10-30) |
| Primary citation | Suzuki, S.,Yanai, H.,Kanagawa, M.,Tamura, S.,Watanabe, Y.,Fuse, K.,Baba, S.,Sampei, G.,Kawai, G. Structure of N-formylglycinamide ribonucleotide amidotransferase II (PurL) from Thermus thermophilus HB8 Acta Crystallogr.,Sect.F, 68:14-19, 2012 Cited by PubMed Abstract: The crystal structure of PurL from Thermus thermophilus HB8 (TtPurL; TTHA1519) was determined in complex with an adenine nucleotide, PO(4)(3-) and Mg(2+) at 2.35 Å resolution. TtPurL consists of 29 α-helices and 28 β-strands, and one loop is disordered. TtPurL consists of four domains, A1, A2, B1 and B2, and the structures of the A1-B1 and A2-B2 domains were almost identical to each other. Although the sequence identity between TtPurL and PurL from Thermotoga maritima (TmPurL) is higher than that between TtPurL and the PurL domain of the large PurL from Salmonella typhimurium (StPurL), the secondary structure of TtPurL is much more similar to that of StPurL than to that of TmPurL. PubMed: 22232163DOI: 10.1107/S1744309111048184 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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