6NBI
 
 | | Cryo-EM structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and G protein | | Descriptor: | CHOLESTEROL, Gs protein alpha subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Zhao, L.-H, Ma, S, Sutkeviciute, I, Shen, D.-D, Zhou, X.E, de Waal, P.P, Li, C.-Y, Kang, Y, Clark, L.J, Jean-Alphonse, F.G, White, A.D, Xiao, K, Yang, D, Jiang, Y, Watanabe, T, Gardella, T.J, Melcher, K, Wang, M.-W, Vilardaga, J.-P, Xu, H.E, Zhang, Y. | | Deposit date: | 2018-12-07 | | Release date: | 2019-04-17 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structure and dynamics of the active human parathyroid hormone receptor-1.
Science, 364, 2019
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7KBV
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7KBW
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6NBH
 | | Cryo-EM structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and G protein | | Descriptor: | CHOLESTEROL, Gs protein alpha subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Zhao, L.-H, Ma, S, Sutkeviciute, I, Shen, D.-D, Zhou, X.E, de Waal, P.P, Li, C.-Y, Kang, Y, Clark, L.J, Jean-Alphonse, F.G, White, A.D, Xiao, K, Yang, D, Jiang, Y, Watanabe, T, Gardella, T.J, Melcher, K, Wang, M.-W, Vilardaga, J.-P, Xu, H.E, Zhang, Y. | | Deposit date: | 2018-12-07 | | Release date: | 2019-04-17 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structure and dynamics of the active human parathyroid hormone receptor-1.
Science, 364, 2019
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7KBX
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1R42
 | | Native Human Angiotensin Converting Enzyme-Related Carboxypeptidase (ACE2) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ZINC ION, ... | | Authors: | Towler, P, Staker, B, Prasad, S.G, Menon, S, Ryan, D, Tang, J, Parsons, T, Fisher, M, Williams, D, Dales, N.A, Patane, M.A, Pantoliano, M.W. | | Deposit date: | 2003-10-07 | | Release date: | 2004-02-03 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis.
J.Biol.Chem., 279, 2004
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1R4L
 | | Inhibitor Bound Human Angiotensin Converting Enzyme-Related Carboxypeptidase (ACE2) | | Descriptor: | (S,S)-2-{1-CARBOXY-2-[3-(3,5-DICHLORO-BENZYL)-3H-IMIDAZOL-4-YL]-ETHYLAMINO}-4-METHYL-PENTANOIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | Authors: | Towler, P, Staker, B, Prasad, S.G, Menon, S, Ryan, D, Tang, J, Parsons, T, Fisher, M, Williams, D, Dales, N.A, Patane, M.A, Pantoliano, M.W. | | Deposit date: | 2003-10-07 | | Release date: | 2004-02-03 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis.
J.Biol.Chem., 279, 2004
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2ML7
 | | Ginsentides: Characterization, Structure and Application of a New Class of Highly Stable Cystine Knot Peptides in Ginseng | | Descriptor: | Specific abundant protein 3 | | Authors: | Wang, S, Nguyen, K, Luo, S, Tam, J, Yang, D. | | Deposit date: | 2014-02-20 | | Release date: | 2015-03-04 | | Last modified: | 2024-11-06 | | Method: | SOLUTION NMR | | Cite: | Ginsentides: Characterization, Structure and Application of a New Class of Highly Stable Cystine Knot Peptides in Ginseng
To be Published
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2LYI
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5XXA
 | | beta-1,4-mannanase-SeMet-RmMan134A | | Descriptor: | endo-1,4-beta-mannanase | | Authors: | Jiang, Z.Q, You, X, Yang, D, Huang, P. | | Deposit date: | 2017-07-03 | | Release date: | 2018-07-25 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | Structure of endo-1,4-beta-mannanase at 1.76 Angstroms resolution.
To Be Published
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5WVP
 | | Expression, characterization and crystal structure of a novel beta-glucosidase from Paenibacillus barengoltzii | | Descriptor: | Beta-glucosidase, beta-D-mannopyranose | | Authors: | Jiang, Z, Wu, S, Yang, D, Qin, Z, You, X, Huang, P. | | Deposit date: | 2016-12-28 | | Release date: | 2018-01-31 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.294 Å) | | Cite: | Expression, characterization and crystal structure of a novel beta-glucosidase from Paenibacillus barengoltzii
To Be Published
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4JCM
 | | Crystal structure of Gamma-CGTASE from Alkalophilic bacillus clarkii at 1.65 Angstrom resolution | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Wu, L, Yang, D, Zhou, J, Wu, J, Chen, J. | | Deposit date: | 2013-02-22 | | Release date: | 2014-02-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | The Crystal Structure of Gamma-Cgtase from Alkalophilic Bacillus Clarkii at 1.65 Angstrom Resolution.
To be Published
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2H25
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8F0V
 | | Lipocalin-like Milk protein-2 - E38A mutant | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Milk protein, ZINC ION | | Authors: | Subramanian, R, KanagaVijayan, D. | | Deposit date: | 2022-11-04 | | Release date: | 2023-08-23 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.951 Å) | | Cite: | Variability in phenylalanine side chain conformations facilitates broad substrate tolerance of fatty acid binding in cockroach milk proteins.
Plos One, 18, 2023
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8F0Y
 | | Lipocalin-like Milk protein-1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Milk protein | | Authors: | Subramanian, R, KanagaVijayan, D, Shantakumar, R.P.S. | | Deposit date: | 2022-11-04 | | Release date: | 2023-08-23 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Variability in phenylalanine side chain conformations facilitates broad substrate tolerance of fatty acid binding in cockroach milk proteins.
Plos One, 18, 2023
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9IVM
 | | Cryo-EM structure of the GLP-1(9-36)-bound human GLP-1R-Gs complex in the presence of LSN3318839 | | Descriptor: | (2~{R})-2-[2-[1-[(1~{R})-1-[2,6-bis(chloranyl)-3-cyclopropyl-phenyl]ethyl]imidazo[4,5-c]pyridin-6-yl]phenyl]propanoic acid, GLP-1(9-36), Glucagon-like peptide 1 receptor, ... | | Authors: | Li, J, Li, G, Mai, Y, Liu, X, Yang, D, Zhou, Q, Wang, M.-W. | | Deposit date: | 2024-07-24 | | Release date: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.22 Å) | | Cite: | Molecular basis of enhanced GLP-1 signaling mediated by GLP-1(9–36) in conjunction with LSN3318839
Acta Pharm Sin B, 2024
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2LBY
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7VU7
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2H35
 | | Solution structure of Human normal adult hemoglobin | | Descriptor: | Hemoglobin alpha subunit, Hemoglobin beta subunit, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Fan, J.S, Yang, D. | | Deposit date: | 2006-05-22 | | Release date: | 2006-11-14 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | A new strategy for structure determination of large proteins in solution without deuteration
Nat.Methods, 3, 2006
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2K3Q
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2L9F
 | | NMR solution structure of meACP | | Descriptor: | CalE8 | | Authors: | Lim, J, Yang, D, Liang, Z.X, Kong, R, Murugan, E, Ho, C.L. | | Deposit date: | 2011-02-08 | | Release date: | 2011-06-15 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution structures of the acyl carrier protein domain from the highly reducing type I iterative polyketide synthase CalE8
Plos One, 6, 2011
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2KBE
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2K3P
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2JPZ
 | | Human telomere DNA quadruplex structure in K+ solution hybrid-2 form | | Descriptor: | DNA (26-MER) | | Authors: | Dai, J, Carver, M, Punchihewa, C, Jones, R, Yang, D. | | Deposit date: | 2007-05-25 | | Release date: | 2007-12-04 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structure of the Hybrid-2 type intramolecular human telomeric G-quadruplex in K+ solution: insights into structure polymorphism of the human telomeric sequence
Nucleic Acids Res., 35, 2007
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2L7V
 | | Quindoline/G-quadruplex complex | | Descriptor: | DNA (5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*A)-3'), N,N-diethyl-N'-(10H-indolo[3,2-b]quinolin-11-yl)ethane-1,2-diamine, POTASSIUM ION | | Authors: | Dai, J, Carver, M, Mathad, R, Yang, D. | | Deposit date: | 2010-12-23 | | Release date: | 2011-11-09 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of a 2:1 Quindoline-c-MYC G-Quadruplex: Insights into G-Quadruplex-Interactive Small Molecule Drug Design.
J.Am.Chem.Soc., 133, 2011
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