8I19
 
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8I8T
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8I1F
 | | Crystal structure of human MTH1(G2K mutant) in complex with 2-oxo-dATP at pH 8.6 | | 分子名称: | 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | | 著者 | Nakamura, T, Yamagata, Y. | | 登録日 | 2023-01-13 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Protonation states of Asp residues in the human Nudix hydrolase MTH1 contribute to its broad substrate recognition.
Febs Lett., 597, 2023
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8I8S
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2Z3Q
 | | Crystal structure of the IL-15/IL-15Ra complex | | 分子名称: | Interleukin-15, Interleukin-15 receptor alpha chain | | 著者 | Chirifu, M, Yamagata, Y, Davis, S.J, Ikemizu, S. | | 登録日 | 2007-06-05 | | 公開日 | 2007-09-04 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal structure of the IL-15-IL-15Ralpha complex, a cytokine-receptor unit presented in trans
Nat.Immunol., 8, 2007
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3APV
 | | Crystal structure of the A variant of human alpha1-acid glycoprotein and amitriptyline complex | | 分子名称: | ACETIC ACID, Alpha-1-acid glycoprotein 2, Amitriptyline | | 著者 | Nishi, K, Ono, T, Nakamura, T, Fukunaga, N, Izumi, M, Watanabe, H, Suenaga, A, Maruyama, T, Yamagata, Y, Curry, S, Otagiri, M. | | 登録日 | 2010-10-21 | | 公開日 | 2011-02-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural insights into differences in drug-binding selectivity between two forms of human alpha1-acid glycoprotein genetic variants, the A and F1*S forms.
J. Biol. Chem., 286, 2011
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3APX
 | | Crystal structure of the A variant of human alpha1-acid glycoprotein and chlorpromazine complex | | 分子名称: | 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine, ACETIC ACID, Alpha-1-acid glycoprotein 2 | | 著者 | Nishi, K, Ono, T, Nakamura, T, Fukunaga, N, Izumi, M, Watanabe, H, Suenaga, A, Maruyama, T, Yamagata, Y, Curry, S, Otagiri, M. | | 登録日 | 2010-10-21 | | 公開日 | 2011-02-23 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural insights into differences in drug-binding selectivity between two forms of human alpha1-acid glycoprotein genetic variants, the A and F1*S forms.
J. Biol. Chem., 286, 2011
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3APW
 | | Crystal structure of the A variant of human alpha1-acid glycoprotein and disopyramide complex | | 分子名称: | Alpha-1-acid glycoprotein 2, Disopyramide | | 著者 | Nishi, K, Ono, T, Nakamura, T, Fukunaga, N, Izumi, M, Watanabe, H, Suenaga, A, Maruyama, T, Yamagata, Y, Curry, S, Otagiri, M. | | 登録日 | 2010-10-21 | | 公開日 | 2011-02-23 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural insights into differences in drug-binding selectivity between two forms of human alpha1-acid glycoprotein genetic variants, the A and F1*S forms.
J. Biol. Chem., 286, 2011
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3APU
 | | Crystal structure of the A variant of human alpha1-acid glycoprotein | | 分子名称: | Alpha-1-acid glycoprotein 2, TETRAETHYLENE GLYCOL | | 著者 | Nishi, K, Ono, T, Nakamura, T, Fukunaga, N, Izumi, M, Watanabe, H, Suenaga, A, Maruyama, T, Yamagata, Y, Curry, S, Otagiri, M. | | 登録日 | 2010-10-21 | | 公開日 | 2011-02-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural insights into differences in drug-binding selectivity between two forms of human alpha1-acid glycoprotein genetic variants, the A and F1*S forms.
J. Biol. Chem., 286, 2011
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1WDW
 | | Structural basis of mutual activation of the tryptophan synthase a2b2 complex from a hyperthermophile, Pyrococcus furiosus | | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, Tryptophan synthase alpha chain, Tryptophan synthase beta chain 1 | | 著者 | Lee, S.J, Ogasahara, K, Ma, J, Nishio, K, Ishida, M, Yamagata, Y, Tsukihara, T, Yutani, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2004-05-19 | | 公開日 | 2005-07-12 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Conformational Changes in the Tryptophan Synthase from a Hyperthermophile upon alpha(2)beta(2) Complex Formation: Crystal Structure of the Complex
Biochemistry, 44, 2005
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1WSF
 | | Co-crystal structure of E.coli RNase HI active site mutant (D134A*) with Mn2+ | | 分子名称: | MANGANESE (II) ION, Ribonuclease HI | | 著者 | Tsunaka, Y, Takano, K, Matsumura, H, Yamagata, Y, Kanaya, S. | | 登録日 | 2004-11-05 | | 公開日 | 2005-02-08 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Identification of Single Mn(2+) Binding Sites Required for Activation of the Mutant Proteins of E.coli RNase HI at Glu48 and/or Asp134 by X-ray Crystallography
J.Mol.Biol., 345, 2005
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1WSE
 | | Co-crystal structure of E.coli RNase HI active site mutant (E48A*) with Mn2+ | | 分子名称: | MANGANESE (II) ION, Ribonuclease HI | | 著者 | Tsunaka, Y, Takano, K, Matsumura, H, Yamagata, Y, Kanaya, S. | | 登録日 | 2004-11-05 | | 公開日 | 2005-02-08 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Identification of Single Mn(2+) Binding Sites Required for Activation of the Mutant Proteins of E.coli RNase HI at Glu48 and/or Asp134 by X-ray Crystallography
J.Mol.Biol., 345, 2005
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1WSG
 | | Co-crystal structure of E.coli RNase HI active site mutant (E48A/D134N*) with Mn2+ | | 分子名称: | MANGANESE (II) ION, Ribonuclease HI | | 著者 | Tsunaka, Y, Takano, K, Matsumura, H, Yamagata, Y, Kanaya, S. | | 登録日 | 2004-11-05 | | 公開日 | 2005-02-08 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Identification of Single Mn(2+) Binding Sites Required for Activation of the Mutant Proteins of E.coli RNase HI at Glu48 and/or Asp134 by X-ray Crystallography
J.Mol.Biol., 345, 2005
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2Z3R
 | | Crystal structure of the IL-15/IL-15Ra complex | | 分子名称: | GLYCEROL, Interleukin-15, Interleukin-15 receptor alpha chain | | 著者 | Chirifu, M, Yamagata, Y, Davis, S.J, Ikemizu, S. | | 登録日 | 2007-06-05 | | 公開日 | 2007-09-04 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the IL-15-IL-15Ralpha complex, a cytokine-receptor unit presented in trans
Nat.Immunol., 8, 2007
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1WUP
 | | Crystal structure of metallo-beta-lactamase IMP-1 mutant (D81E) | | 分子名称: | ACETIC ACID, Beta-lactamase IMP-1, ZINC ION | | 著者 | Yamaguchi, Y, Yamagata, Y, Goto, M. | | 登録日 | 2004-12-08 | | 公開日 | 2005-03-29 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Probing the role of Asp-120(81) of metallo-beta-lactamase (IMP-1) by site-directed mutagenesis, kinetic studies, and X-ray crystallography.
J.Biol.Chem., 280, 2005
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1WUO
 | | Crystal structure of metallo-beta-lactamase IMP-1 mutant (D81A) | | 分子名称: | ACETIC ACID, Beta-lactamase IMP-1, ZINC ION | | 著者 | Yamaguchi, Y, Yamagata, Y, Goto, M. | | 登録日 | 2004-12-08 | | 公開日 | 2005-03-29 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Probing the role of Asp-120(81) of metallo-beta-lactamase (IMP-1) by site-directed mutagenesis, kinetic studies, and X-ray crystallography.
J.Biol.Chem., 280, 2005
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2DOO
 | | The structure of IMP-1 complexed with the detecting reagent (DansylC4SH) by a fluorescent probe | | 分子名称: | BETA-LACTAMASE IMP-1, N-[4-({[5-(DIMETHYLAMINO)-1-NAPHTHYL]SULFONYL}AMINO)BUTYL]-3-SULFANYLPROPANAMIDE, ZINC ION | | 著者 | Kurosaki, H, Yamaguchi, Y, Yasuzawa, H, Jin, W, Yamagata, Y, Arakawa, Y. | | 登録日 | 2006-05-01 | | 公開日 | 2006-11-28 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | | 主引用文献 | Probing, inhibition, and crystallographic characterization of metallo-beta-lactamase (IMP-1) with fluorescent agents containing dansyl and thiol groups
Chemmedchem, 1, 2006
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3A6V
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3A6T
 | | Crystal structure of MutT-8-OXO-DGMP complex | | 分子名称: | 8-OXO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE, Mutator mutT protein, SODIUM ION, ... | | 著者 | Nakamura, T, Yamagata, Y. | | 登録日 | 2009-09-09 | | 公開日 | 2009-10-27 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Structural and dynamic features of the MutT protein in the recognition of nucleotides with the mutagenic 8-oxoguanine base
J.Biol.Chem., 285, 2010
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3A6S
 | | Crystal structure of the MutT protein | | 分子名称: | L(+)-TARTARIC ACID, Mutator mutT protein, SODIUM ION | | 著者 | Nakamura, T, Yamagata, Y. | | 登録日 | 2009-09-09 | | 公開日 | 2009-10-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural and dynamic features of the MutT protein in the recognition of nucleotides with the mutagenic 8-oxoguanine base
J.Biol.Chem., 285, 2010
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3AC9
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3ACA
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3A6U
 | | Crystal structure of MutT-8-OXO-dGMP-MN(II) complex | | 分子名称: | 8-OXO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, Mutator mutT protein, ... | | 著者 | Nakamura, T, Yamagata, Y. | | 登録日 | 2009-09-09 | | 公開日 | 2009-10-27 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | Structural and dynamic features of the MutT protein in the recognition of nucleotides with the mutagenic 8-oxoguanine base
J.Biol.Chem., 285, 2010
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2E7A
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3A4F
 | | Crystal Structure of Human Transthyretin (E54K) | | 分子名称: | GLYCEROL, SULFATE ION, Transthyretin | | 著者 | Miyata, M, Sato, T, Nakamura, T, Ikemizu, S, Yamagata, Y, Kai, H. | | 登録日 | 2009-07-06 | | 公開日 | 2009-12-22 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Role of the glutamic acid 54 residue in transthyretin stability and thyroxine binding
Biochemistry, 49, 2010
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