3APV
Crystal structure of the A variant of human alpha1-acid glycoprotein and amitriptyline complex
Summary for 3APV
| Entry DOI | 10.2210/pdb3apv/pdb |
| Related | 3APU 3APW 3APX |
| Descriptor | Alpha-1-acid glycoprotein 2, Amitriptyline, ACETIC ACID, ... (4 entities in total) |
| Functional Keywords | beta barrel, plasma protein, transport protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 45997.43 |
| Authors | Nishi, K.,Ono, T.,Nakamura, T.,Fukunaga, N.,Izumi, M.,Watanabe, H.,Suenaga, A.,Maruyama, T.,Yamagata, Y.,Curry, S.,Otagiri, M. (deposition date: 2010-10-21, release date: 2011-02-23, Last modification date: 2023-11-01) |
| Primary citation | Nishi, K.,Ono, T.,Nakamura, T.,Fukunaga, N.,Izumi, M.,Watanabe, H.,Suenaga, A.,Maruyama, T.,Yamagata, Y.,Curry, S.,Otagiri, M. Structural insights into differences in drug-binding selectivity between two forms of human alpha1-acid glycoprotein genetic variants, the A and F1*S forms. J. Biol. Chem., 286:14427-14434, 2011 Cited by PubMed: 21349832DOI: 10.1074/jbc.M110.208926 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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