3APV
Crystal structure of the A variant of human alpha1-acid glycoprotein and amitriptyline complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Alpha-1-acid glycoprotein 2 | polymer | 190 | 22691.3 | 2 | UniProt (P19652) Pfam (PF00061) | Homo sapiens (human) | AGP 2, Orosomucoid-2, OMD 2 |
| 2 | C, E (A, B) | Amitriptyline | non-polymer | 277.4 | 2 | Chemie (TP0) | |||
| 3 | D (A) | ACETIC ACID | non-polymer | 60.1 | 1 | Chemie (ACY) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 96 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 183 (UniProt: P19652)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | expression tag |
| Arg 149 | Cys 167 | engineered mutation |
| His 184 | - | expression tag |
| His 185 | - | expression tag |
| His 186 | - | expression tag |
| His 187 | - | expression tag |
| His 188 | - | expression tag |
| His 189 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 45382.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 614.9 | |
| All* | Total formula weight | 45997.4 |
