1WUP

Crystal structure of metallo-beta-lactamase IMP-1 mutant (D81E)

Summary for 1WUP

• Entry DOI: 10.2210/pdb1wup/pdb
• Related: 1WUO
• Descriptor: Beta-lactamase IMP-1, ZINC ION, ACETIC ACID (3 entities in total)
• Functional Keywords: metallo-beta-lactamase, hydrolysis, aspartic acid, hydrolase
• Biological source: Serratia marcescens
• Cellular location: Periplasm : P52699
• Total number of polymer chains: 4
• Total formula weight: 101406.28

Authors

Yamaguchi, Y.,Yamagata, Y.,Goto, M. (deposition date: 2004-12-08, release date: 2005-03-29, Last modification date: 2023-10-25)

• Primary citation: Yamaguchi, Y.,Kuroki, T.,Yasuzawa, H.,Higashi, T.,Jin, W.,Kawanami, A.,Yamagata, Y.,Arakawa, Y.,Goto, M.,Kurosaki, H.; Probing the role of Asp-120(81) of metallo-beta-lactamase (IMP-1) by site-directed mutagenesis, kinetic studies, and X-ray crystallography.; J.Biol.Chem., 280:20824-20832, 2005; PubMed: 15788415; DOI: 10.1074/jbc.M414314200

Experimental method

X-RAY DIFFRACTION (3 Å)