1WSG
Co-crystal structure of E.coli RNase HI active site mutant (E48A/D134N*) with Mn2+
Summary for 1WSG
Entry DOI | 10.2210/pdb1wsg/pdb |
Related | 1WSE 1WSF 1WSH 1WSI 1WSJ |
Descriptor | Ribonuclease HI, MANGANESE (II) ION (3 entities in total) |
Functional Keywords | rnase h, active-site mutant, co-crystal structure with mn2+, metal fluctuation model, hydrolase |
Biological source | Escherichia coli |
Cellular location | Cytoplasm (Potential): P0A7Y4 |
Total number of polymer chains | 4 |
Total formula weight | 70133.37 |
Authors | Tsunaka, Y.,Takano, K.,Matsumura, H.,Yamagata, Y.,Kanaya, S. (deposition date: 2004-11-05, release date: 2005-02-08, Last modification date: 2024-05-29) |
Primary citation | Tsunaka, Y.,Takano, K.,Matsumura, H.,Yamagata, Y.,Kanaya, S. Identification of Single Mn(2+) Binding Sites Required for Activation of the Mutant Proteins of E.coli RNase HI at Glu48 and/or Asp134 by X-ray Crystallography J.Mol.Biol., 345:1171-1183, 2005 Cited by PubMed: 15644213DOI: 10.1016/j.jmb.2004.11.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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