1WSG
Co-crystal structure of E.coli RNase HI active site mutant (E48A/D134N*) with Mn2+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Ribonuclease HI | polymer | 155 | 17505.9 | 4 | UniProt (P0A7Y4) Pfam (PF00075) | Escherichia coli | RNase HI, Ribonuclease H, RNase H |
| 2 | E, F (A, D) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 3 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 357 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 155 (UniProt: P0A7Y4)
| PDB | External Database | Details |
|---|---|---|
| Ala 48 | Glu 48 | engineered mutation |
| Ala 87 | Lys 87 | engineered mutation |
| Asn 134 | Asp 134 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 70023.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 109.9 | |
| All* | Total formula weight | 70133.4 |
