6PT0
 
 | | Cryo-EM structure of human cannabinoid receptor 2-Gi protein in complex with agonist WIN 55,212-2 | | 分子名称: | CHOLESTEROL, Cannabinoid receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Xu, T.H, Xing, C, Zhuang, Y, Feng, Z, Zhou, X.E, Chen, M, Wang, L, Meng, X, Xue, Y, Wang, J, Liu, H, McGuire, T, Zhao, G, Melcher, K, Zhang, C, Xu, H.E, Xie, X.Q. | | 登録日 | 2019-07-14 | | 公開日 | 2020-02-12 | | 最終更新日 | 2020-03-04 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM Structure of the Human Cannabinoid Receptor CB2-GiSignaling Complex.
Cell, 180, 2020
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1SPI
 | | CRYSTAL STRUCTURE OF SPINACH CHLOROPLAST FRUCTOSE-1,6-BISPHOSPHATASE AT 2.8 ANGSTROMS RESOLUTION | | 分子名称: | FRUCTOSE 1,6-BISPHOSPHATASE | | 著者 | Villeret, V, Huang, S, Zhang, Y, Xue, Y, Lipscomb, W.N. | | 登録日 | 1994-12-14 | | 公開日 | 1995-02-27 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of spinach chloroplast fructose-1,6-bisphosphatase at 2.8 A resolution.
Biochemistry, 34, 1995
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7XC8
 | | Crystal structure of cotton alpha-like expansin GhEXLA1 | | 分子名称: | Beta-expansin, DI(HYDROXYETHYL)ETHER, GLYCEROL | | 著者 | Zhao, F, Men, S, Xue, Y, Tu, L.L, Yin, P, Zhang, X.L. | | 登録日 | 2022-03-23 | | 公開日 | 2023-05-17 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Crystal structure of cotton alpha-like expansin GhEXLA1
To Be Published
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1GR7
 | | Crystal structure of the double mutant Cys3Ser/Ser100Pro from Pseudomonas Aeruginosa at 1.8 A resolution | | 分子名称: | AZURIN, COPPER (II) ION | | 著者 | Okvist, M, Bonander, N, Sandberg, A, Karlsson, B.G, Krengel, U, Xue, Y, Sjolin, L. | | 登録日 | 2001-12-14 | | 公開日 | 2002-05-16 | | 最終更新日 | 2019-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of the double azurin mutant Cys3Ser/Ser100Pro from Pseudomonas aeruginosa at 1.8 A resolution: its folding-unfolding energy and unfolding kinetics.
Biochim.Biophys.Acta, 1596, 2002
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1A8M
 | | TUMOR NECROSIS FACTOR ALPHA, R31D MUTANT | | 分子名称: | TUMOR NECROSIS FACTOR ALPHA | | 著者 | Reed, C, Fu, Z.-Q, Wu, J, Xue, Y.-N, Harrison, R.W, Chen, M.-J, Weber, I.T. | | 登録日 | 1998-03-27 | | 公開日 | 1998-06-17 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of TNF-alpha mutant R31D with greater affinity for receptor R1 compared with R2.
Protein Eng., 10, 1997
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4NZ2
 | | Crystal structure of CYP2C9 in complex with an inhibitor | | 分子名称: | (2R)-N-{4-[(3-bromophenyl)sulfonyl]-2-chlorophenyl}-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide, Cytochrome P450 2C9, GLYCEROL, ... | | 著者 | Branden, G, Sjogren, T, Xue, Y. | | 登録日 | 2013-12-11 | | 公開日 | 2014-08-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structure-based ligand design to overcome CYP inhibition in drug discovery projects.
Drug Discov Today, 19, 2014
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1FNK
 | | CRYSTAL STRUCTURE ANALYSIS OF CHORISMATE MUTASE MUTANT C88K/R90S | | 分子名称: | PROTEIN (CHORISMATE MUTASE) | | 著者 | Kast, P, Grisostomi, C, Chen, I.A, Li, S, Krengel, U, Xue, Y, Hilvert, D. | | 登録日 | 2000-08-22 | | 公開日 | 2000-10-11 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A strategically positioned cation is crucial for efficient catalysis by chorismate mutase.
J.Biol.Chem., 275, 2000
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1FNJ
 | | CRYSTAL STRUCTURE ANALYSIS OF CHORISMATE MUTASE MUTANT C88S/R90K | | 分子名称: | PROTEIN (CHORISMATE MUTASE) | | 著者 | Kast, P, Grisostomi, C, Chen, I.A, Li, S, Krengel, U, Xue, Y, Hilvert, D. | | 登録日 | 2000-08-22 | | 公開日 | 2000-10-11 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A strategically positioned cation is crucial for efficient catalysis by chorismate mutase.
J.Biol.Chem., 275, 2000
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1M61
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3W21
 | | Crystal Structure of a Novel N-Substituted L-Amino Acid Dioxygenase in complex with alpha-KG from Burkholderia ambifaria AMMD | | 分子名称: | 2-OXOGLUTARIC ACID, Putative uncharacterized protein, ZINC ION | | 著者 | Qin, H.M, Miyakawa, T, Jia, M.Z, Nakamura, A, Ohtsuka, J, Xue, Y.L, Kawashima, T, Kasahara, T, Hibi, M, Ogawa, J, Tanokura, M. | | 登録日 | 2012-11-26 | | 公開日 | 2013-07-17 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Crystal Structure of a Novel N-Substituted L-Amino Acid Dioxygenase from Burkholderia ambifaria AMMD
Plos One, 8, 2013
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1Q07
 | | Crystal structure of the Au(I) form of E. coli CueR, a copper efflux regulator | | 分子名称: | GOLD ION, Transcriptional regulator cueR | | 著者 | Changela, A, Chen, K, Xue, Y, Holschen, J, Outten, C.E, O'Halloran, T.V, Mondragon, A. | | 登録日 | 2003-07-15 | | 公開日 | 2003-09-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Molecular basis of metal-ion selectivity and zeptomolar sensitivity by CueR
Science, 301, 2003
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1Q06
 | | Crystal structure of the Ag(I) form of E. coli CueR, a copper efflux regulator | | 分子名称: | SILVER ION, Transcriptional regulator cueR | | 著者 | Changela, A, Chen, K, Xue, Y, Holschen, J, Outten, C.E, O'Halloran, T.V, Mondragon, A. | | 登録日 | 2003-07-15 | | 公開日 | 2003-09-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Molecular basis of metal-ion selectivity and zeptomolar sensitivity by CueR
Science, 301, 2003
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6DU3
 | | Structure of Scp1 D96N bound to REST-pS861/4 peptide | | 分子名称: | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION, REST-pS861 | | 著者 | Burkholder, N.T, Mayfield, J.E, Yu, X, Irani, S, Arce, D.K, Jiang, F, Matthews, W, Xue, Y, Zhang, Y.J. | | 登録日 | 2018-06-19 | | 公開日 | 2018-09-26 | | 最終更新日 | 2020-01-01 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST).
J. Biol. Chem., 293, 2018
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6DU2
 | | Structure of Scp1 D96N bound to REST-pS861/4 peptide | | 分子名称: | MAGNESIUM ION, REST-pS861/4, carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform X2 | | 著者 | Burkholder, N.T, Mayfield, J.E, Yu, X, Irani, S, Arce, D.K, Jiang, F, Matthews, W, Xue, Y, Zhang, Y.J. | | 登録日 | 2018-06-19 | | 公開日 | 2018-09-26 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST).
J. Biol. Chem., 293, 2018
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3W20
 | | Crystal Structure of a Novel N-Substituted L-Amino Acid Dioxygenase from Burkholderia ambifaria AMMD | | 分子名称: | Putative uncharacterized protein, ZINC ION | | 著者 | Qin, H.M, Miyakawa, T, Jia, M.Z, Nakamura, A, Ohtsuka, J, Xue, Y.L, Kawashima, T, Kasahara, T, Hibi, M, Ogawa, J, Tanokura, M. | | 登録日 | 2012-11-26 | | 公開日 | 2013-07-17 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Crystal Structure of a Novel N-Substituted L-Amino Acid Dioxygenase from Burkholderia ambifaria AMMD
Plos One, 8, 2013
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1Q08
 | | Crystal structure of the Zn(II) form of E. coli ZntR, a zinc-sensing transcriptional regulator, at 1.9 A resolution (space group P212121) | | 分子名称: | MAGNESIUM ION, PHOSPHATE ION, ZINC ION, ... | | 著者 | Changela, A, Chen, K, Xue, Y, Holschen, J, Outten, C.E, O'Halloran, T.V, Mondragon, A. | | 登録日 | 2003-07-15 | | 公開日 | 2003-09-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Molecular basis of metal-ion selectivity and zeptomolar sensitivity by CueR
Science, 301, 2003
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2B1P
 | | inhibitor complex of JNK3 | | 分子名称: | 3-{6-[(2-CHLOROPHENYL)AMINO]-1H-INDAZOL-3-YL}-5-{[4-(DIMETHYLAMINO)BUTANOYL]AMINO}BENZOIC ACID, BETA-MERCAPTOETHANOL, Mitogen-activated protein kinase 10, ... | | 著者 | Swahn, B.M, Huerta, F, Kallin, E, Malmstrom, J, Weigelt, T, Viklund, J, Womack, P, Xue, Y, Ohberg, L. | | 登録日 | 2005-09-16 | | 公開日 | 2006-09-16 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Design and synthesis of 6-anilinoindazoles as selective inhibitors of c-Jun N-terminal kinase-3
Bioorg.Med.Chem.Lett., 15, 2005
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1OPS
 | | ICE-BINDING SURFACE ON A TYPE III ANTIFREEZE PROTEIN FROM OCEAN POUT | | 分子名称: | TYPE III ANTIFREEZE PROTEIN | | 著者 | Yang, D.S.C, Hon, W.-C, Bubanko, S, Xue, Y, Seetharaman, J, Hew, C.L, Sicheri, F. | | 登録日 | 1997-11-17 | | 公開日 | 1998-05-20 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Identification of the ice-binding surface on a type III antifreeze protein with a "flatness function" algorithm.
Biophys.J., 74, 1998
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1Q05
 | | Crystal structure of the Cu(I) form of E. coli CueR, a copper efflux regulator | | 分子名称: | COPPER (I) ION, Transcriptional regulator cueR | | 著者 | Changela, A, Chen, K, Xue, Y, Holschen, J, Outten, C.E, O'Halloran, T.V, Mondragon, A. | | 登録日 | 2003-07-15 | | 公開日 | 2003-09-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Molecular basis of metal-ion selectivity and zeptomolar sensitivity by CueR
Science, 301, 2003
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4NY4
 | | Crystal structure of CYP3A4 in complex with an inhibitor | | 分子名称: | (8R)-3,3-difluoro-8-[4-fluoro-3-(pyridin-3-yl)phenyl]-8-(4-methoxy-3-methylphenyl)-2,3,4,8-tetrahydroimidazo[1,5-a]pyrimidin-6-amine, Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Branden, G, Sjogren, T, Xue, Y. | | 登録日 | 2013-12-10 | | 公開日 | 2014-08-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structure-based ligand design to overcome CYP inhibition in drug discovery projects.
Drug Discov Today, 19, 2014
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4IXL
 | | Crystal structure of endo-beta-1,4-xylanase from the alkaliphilic Bacillus sp. SN5 | | 分子名称: | SULFATE ION, xylanase | | 著者 | Bai, W.Q, Xue, Y.F, Huang, J.X, Zhou, C, Guo, R.T, Ma, Y.H. | | 登録日 | 2013-01-26 | | 公開日 | 2014-02-12 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Structure Analysis of Alkaline xylanase from Alkaliphilic Bacillus sp. SN5 Implications for pH-dependent enzyme activity
To be Published
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1CAY
 | | WILD-TYPE AND E106Q MUTANT CARBONIC ANHYDRASE COMPLEXED WITH ACETATE | | 分子名称: | ACETIC ACID, CARBONIC ANHYDRASE II, ZINC ION | | 著者 | Hakansson, K, Briand, C, Zaitsev, V, Xue, Y, Liljas, A. | | 登録日 | 1993-02-26 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Wild-type and E106Q mutant carbonic anhydrase complexed with acetate.
Acta Crystallogr.,Sect.D, 50, 1994
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1CAZ
 | | WILD-TYPE AND E106Q MUTANT CARBONIC ANHYDRASE COMPLEXED WITH ACETATE | | 分子名称: | ACETIC ACID, CARBONIC ANHYDRASE II, ZINC ION | | 著者 | Hakansson, K, Briand, C, Zaitsev, V, Xue, Y, Liljas, A. | | 登録日 | 1993-02-26 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Wild-type and E106Q mutant carbonic anhydrase complexed with acetate.
Acta Crystallogr.,Sect.D, 50, 1994
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7Y1Q
 | | 5.0 angstrom cryo-EM structure of transmembrane regions of mouse Basigin/MCT1 in complex with antibody 6E7F1 | | 分子名称: | Isoform 2 of Basigin, Monocarboxylate transporter 1 | | 著者 | Zhang, H, Yang, X, Xue, Y, Huang, Y, Mo, X, Zhang, H, Li, N, Gao, N, Li, X, Wang, S, Gao, Y, Liao, J. | | 登録日 | 2022-06-08 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (5.03 Å) | | 主引用文献 | Allosteric modulation of monocarboxylate transporters 1 and 4 by targeting their chaperon Basigin-2
To Be Published
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7Y1B
 | | 3.2 angstrom cryo-EM structure of extracellular region of mouse Basigin-2 in complex with the Fab fragment of antibody 6E7F1 | | 分子名称: | Heavy chain of 6E7F1, Isoform 2 of Basigin, Light chain of 6E7F1 | | 著者 | Zhang, H, Yang, X, Xue, Y, Huang, Y, Mo, X, Zhang, H, Li, N, Gao, N, Li, X, Wang, S, Gao, Y, Liao, J. | | 登録日 | 2022-06-08 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | | 主引用文献 | Allosteric modulation of monocarboxylate transporters 1 and 4 by targeting their chaperon Basigin
To Be Published
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