2B1P

inhibitor complex of JNK3

Summary for 2B1P

Entry DOI	10.2210/pdb2b1p/pdb
Descriptor	Mitogen-activated protein kinase 10, SULFATE ION, 3-{6-[(2-CHLOROPHENYL)AMINO]-1H-INDAZOL-3-YL}-5-{[4-(DIMETHYLAMINO)BUTANOYL]AMINO}BENZOIC ACID, ... (5 entities in total)
Functional Keywords	enzyme-inhibitor complex, kinase inhibitor, transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P53779
Total number of polymer chains	1
Total formula weight	41731.72
Authors	Swahn, B.M.,Huerta, F.,Kallin, E.,Malmstrom, J.,Weigelt, T.,Viklund, J.,Womack, P.,Xue, Y.,Ohberg, L. (deposition date: 2005-09-16, release date: 2006-09-16, Last modification date: 2024-03-13)
Primary citation	Swahn, B.M.,Huerta, F.,Kallin, E.,Malmstrom, J.,Weigelt, T.,Viklund, J.,Womack, P.,Xue, Y.,Ohberg, L. Design and synthesis of 6-anilinoindazoles as selective inhibitors of c-Jun N-terminal kinase-3 Bioorg.Med.Chem.Lett., 15:5095-5099, 2005 Cited by PubMed: 16140012 DOI: 10.1016/j.bmcl.2005.06.083 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation