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6DU3

Structure of Scp1 D96N bound to REST-pS861/4 peptide

Summary for 6DU3
Entry DOI10.2210/pdb6du3/pdb
Related6DU2
DescriptorCarboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, REST-pS861, MAGNESIUM ION, ... (4 entities in total)
Functional Keywordsphosphatase, transcription factor, phosphorylation, neurogenesis, hydrolase, hydrolase-peptide complex, hydrolase/peptide
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains4
Total formula weight44240.67
Authors
Burkholder, N.T.,Mayfield, J.E.,Yu, X.,Irani, S.,Arce, D.K.,Jiang, F.,Matthews, W.,Xue, Y.,Zhang, Y.J. (deposition date: 2018-06-19, release date: 2018-09-26, Last modification date: 2020-01-01)
Primary citationBurkholder, N.T.,Mayfield, J.E.,Yu, X.,Irani, S.,Arce, D.K.,Jiang, F.,Matthews, W.L.,Xue, Y.,Zhang, Y.J.
Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST).
J. Biol. Chem., 293:16851-16861, 2018
Cited by
PubMed: 30217818
DOI: 10.1074/jbc.RA118.004722
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.58 Å)
Structure validation

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