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PDB: 14 results

1B87
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BU of 1b87 by Molmil
CRYSTAL STRUCTURE OF AN AMINOGLYCOSIDE 6'-N-ACETYLTRANSFERASE
Descriptor: ACETYL COENZYME *A, PROTEIN (AMINOGLYCOSIDE N6'-ACETYLTRANSFERASE TYPE 1)
Authors:Wybenga-Groot, L.E, Berghuis, A.M.
Deposit date:1999-02-09
Release date:1999-06-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of an aminoglycoside 6'-N-acetyltransferase: defining the GCN5-related N-acetyltransferase superfamily fold.
Structure Fold.Des., 7, 1999
6XAR
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Structure of CBL tyrosine kinase binding domain (TKBD) with C-terminal tail of Src-like kinase protein 2 (SLAP2)
Descriptor: CALCIUM ION, E3 ubiquitin-protein ligase CBL, Src-like-adapter 2
Authors:Wybenga-Groot, L.E, McGlade, C.J.
Deposit date:2020-06-04
Release date:2021-03-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:SLAP2 Adaptor Binding Disrupts c-CBL Autoinhibition to Activate Ubiquitin Ligase Function.
J.Mol.Biol., 433, 2021
4TZI
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Structure of unliganded Lyn SH2 domain
Descriptor: Tyrosine-protein kinase Lyn
Authors:Wybenga-Groot, L.E.
Deposit date:2014-07-10
Release date:2015-01-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Tyrosine Phosphorylation of the Lyn Src Homology 2 (SH2) Domain Modulates Its Binding Affinity and Specificity.
Mol.Cell Proteomics, 14, 2015
1JPA
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Crystal Structure of unphosphorylated EphB2 receptor tyrosine kinase and juxtamembrane region
Descriptor: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, neural kinase, Nuk=Eph/Elk/Eck family receptor-like tyrosine kinase
Authors:Wybenga-Groot, L.E, Pawson, T, Sicheri, F.
Deposit date:2001-08-01
Release date:2001-10-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region.
Cell(Cambridge,Mass.), 106, 2001
4M4Z
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SH3 and SH2 domains of human Src-like adaptor protein 2 (SLAP2)
Descriptor: Src-like-adapter 2
Authors:Wybenga-Groot, L.E, McGlade, C.J.
Deposit date:2013-08-07
Release date:2013-11-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of Src-like adaptor protein 2 reveals close association of SH3 and SH2 domains through beta-sheet formation.
Cell Signal, 25, 2013
4PDP
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Crystal structure of Rad53 kinase domain and SCD2
Descriptor: Serine/threonine-protein kinase RAD53
Authors:Wybenga-Groot, L.E, Ho, C.S, Ceccarelli, D.F, Sicheri, F.
Deposit date:2014-04-19
Release date:2014-05-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.591 Å)
Cite:Structural basis of Rad53 kinase activation by dimerization and activation segment exchange.
Cell Signal., 26, 2014
2HEN
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Crystal Structure of the EphB2 Receptor Kinase domain in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Ephrin type-B receptor 2, MAGNESIUM ION
Authors:Wybenga-Groot, L.E, Sicheri, F, Pawson, T.
Deposit date:2006-06-21
Release date:2007-02-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A change in conformational dynamics underlies the activation of Eph receptor tyrosine kinases
EMBO J., 25, 2006
2HEL
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Crystal structure of a mutant EphA4 kinase domain (Y742A)
Descriptor: Eph receptor A4
Authors:Wybenga-Groot, L.E, Sicheri, F, Pawson, T.
Deposit date:2006-06-21
Release date:2007-02-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:A change in conformational dynamics underlies the activation of Eph receptor tyrosine kinases.
EMBO J., 25, 2006
1N71
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Crystal structure of aminoglycoside 6'-acetyltransferase type Ii in complex with coenzyme A
Descriptor: COENZYME A, SULFATE ION, aac(6')-Ii
Authors:Burk, D.L, Ghuman, N, Wybenga-Groot, L.E, Berghuis, A.M.
Deposit date:2002-11-12
Release date:2003-03-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray structure of the AAC(6')-Ii antibiotic resistance enzyme at 1.8 A resolution; examination of oligomeric arrangements in GNAT superfamily members
Protein Sci., 12, 2003
2H6D
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BU of 2h6d by Molmil
Protein Kinase Domain of the Human 5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK alpha-2 chain)
Descriptor: 5'-AMP-activated protein kinase catalytic subunit alpha-2
Authors:Littler, D.R, Walker, J.R, Wybenga-Groot, L, Newman, E.M, Butler-Cole, C, Mackenzie, F, Finerty, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2006-05-31
Release date:2006-06-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A conserved mechanism of autoinhibition for the AMPK kinase domain: ATP-binding site and catalytic loop refolding as a means of regulation.
Acta Crystallogr.,Sect.F, 66, 2010
4PDS
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Crystal structure of Rad53 kinase domain and SCD2 in complex with AMPPNP
Descriptor: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase RAD53
Authors:Ho, C.S, Wybenga-Groot, L.E, Ceccarelli, D.F, Sicheri, F.
Deposit date:2014-04-21
Release date:2014-05-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of Rad53 kinase activation by dimerization and activation segment exchange.
Cell Signal., 26, 2014
2FAZ
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BU of 2faz by Molmil
Ubiquitin-Like Domain of Human Nuclear Zinc Finger Protein NP95
Descriptor: Ubiquitin-like containing PHD and RING finger domains protein 1
Authors:Walker, J.R, Wybenga-Groot, L, Doherty, R.S, Finerty Jr, P.J, Newman, E, Mackenzie, F.M, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2005-12-08
Release date:2005-12-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Ubiquitin-Like Domain of Human Nuclear Zinc Finger Protein NP95
To be Published
2F15
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Glycogen-Binding Domain Of The Amp-Activated Protein Kinase beta2 Subunit
Descriptor: 5'-AMP-activated protein kinase, beta-2 subunit
Authors:Walker, J.R, Wybenga-Groot, L, Finerty Jr, P.J, Newman, E, MacKenzie, F.M, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2005-11-14
Release date:2005-12-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the Glycogen-Binding Domain Of The Amp-Activated Protein Kinase beta2 Subunit
To be Published
2G7R
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X-ray structure of the death domain of the human mucosa associated lymphoid tissue lymphoma translocation protein 1
Descriptor: Mucosa-associated lymphoid tissue lymphoma translocation protein 1
Authors:Walker, J.R, Wybenga-Groot, L, Newman, E.M, Finerty Jr, P.J, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2006-02-28
Release date:2006-04-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:X-ray structure of the death domain of the human mucosa associated lymphoid tissue lymphoma translocation protein 1
To be Published

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