1JPA
Crystal Structure of unphosphorylated EphB2 receptor tyrosine kinase and juxtamembrane region
Summary for 1JPA
Entry DOI | 10.2210/pdb1jpa/pdb |
Descriptor | neural kinase, Nuk=Eph/Elk/Eck family receptor-like tyrosine kinase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER (3 entities in total) |
Functional Keywords | receptor tyrosine kinase, autoinhibited, unphosphorylated, juxtamembrane, transferase |
Biological source | Mus musculus (house mouse) |
Cellular location | Membrane; Single-pass type I membrane protein: P54763 |
Total number of polymer chains | 2 |
Total formula weight | 71661.32 |
Authors | Wybenga-Groot, L.E.,Pawson, T.,Sicheri, F. (deposition date: 2001-08-01, release date: 2001-10-03, Last modification date: 2024-04-03) |
Primary citation | Wybenga-Groot, L.E.,Baskin, B.,Ong, S.H.,Tong, J.,Pawson, T.,Sicheri, F. Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region. Cell(Cambridge,Mass.), 106:745-757, 2001 Cited by PubMed: 11572780DOI: 10.1016/S0092-8674(01)00496-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.91 Å) |
Structure validation
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