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PDB: 388 件

1NE6
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Crystal structure of Sp-cAMP binding R1a subunit of cAMP-dependent protein kinase
分子名称: 6-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL, cAMP-dependent protein kinase type I-alpha regulatory chain
著者Wu, J, Jones, J.M, Xuong, N.H, Taylor, S.S.
登録日2002-12-10
公開日2004-01-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structures of RIalpha Subunit of Cyclic Adenosine 5'-Monophosphate (cAMP)-Dependent Protein Kinase Complexed with (R(p))-Adenosine 3',5'-Cyclic Monophosphothioate and (S(p))-Adenosine 3',5'-Cyclic Monophosphothioate, the Phosphothioate Analogues of cAMP.
Biochemistry, 43, 2004
2P6G
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Crystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA and inhibitors
分子名称: 1-(CYCLOHEXYLAMINO)-3-(6-METHYL-3,4-DIHYDRO-1H-CARBAZOL-9(2H)-YL)PROPAN-2-OL, Glycylpeptide N-tetradecanoyltransferase, TETRADECANOYL-COA
著者Wu, J, Ding, J.
登録日2007-03-18
公開日2007-06-12
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA and inhibitors reveal the functional roles of the N-terminal region.
J.Biol.Chem., 282, 2007
2P6F
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Crystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA and inhibitors
分子名称: (Z)-3-BENZYL-5-(2-HYDROXY-3-NITROBENZYLIDENE)-2-THIOXOTHIAZOLIDIN-4-ONE, Glycylpeptide N-tetradecanoyltransferase, TETRADECANOYL-COA
著者Wu, J, Ding, J.
登録日2007-03-18
公開日2007-06-12
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA and inhibitors reveal the functional roles of the N-terminal region.
J.Biol.Chem., 282, 2007
5IC0
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Structural analysis of a talin triple domain module
分子名称: 1,2-ETHANEDIOL, Talin-1
著者Wu, J, Chang, Y.-C.E, Zhang, H, Brennan, M.L.
登録日2016-02-22
公開日2016-05-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural and Functional Analysis of a Talin Triple-Domain Module Suggests an Alternative Talin Autoinhibitory Configuration.
Structure, 24, 2016
5IC1
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Structural analysis of a talin triple domain module, E1794Y, E1797Y, Q1801Y mutant
分子名称: 1,2-ETHANEDIOL, Talin-1
著者Wu, J, Chang, Y.-C.E, Zhang, H, Huang, Q.-Q.
登録日2016-02-22
公開日2016-05-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and Functional Analysis of a Talin Triple-Domain Module Suggests an Alternative Talin Autoinhibitory Configuration.
Structure, 24, 2016
7VCF
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Cryo-EM structure of Chlamydomonas TOC-TIC supercomplex
分子名称: 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
著者Wu, J, Yan, Z, Jin, Z, Zhang, Y.
登録日2021-09-02
公開日2022-11-30
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Structure of a TOC-TIC supercomplex spanning two chloroplast envelope membranes.
Cell, 185, 2022
4IBM
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Crystal structure of insulin receptor kinase domain in complex with an inhibitor Irfin-1
分子名称: 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-3H-pyrazolo[3,4-c]pyridazin-3-one, Insulin receptor
著者Wu, J, Anastassiadis, T, Duong-Ly, K.C, Peterson, J.R.
登録日2012-12-08
公開日2013-08-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A highly selective dual insulin receptor (IR)/insulin-like growth factor 1 receptor (IGF-1R) inhibitor derived from an extracellular signal-regulated kinase (ERK) inhibitor.
J.Biol.Chem., 288, 2013
7YAO
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Crystal structure of a bright green fluorescent protein (oxStayGold) in jellyfish Cytaeis uchidae from Biortus
分子名称: oxstaygold
著者Wu, J, Wang, F, Gui, W, Cheng, W, Yang, Y.
登録日2022-06-28
公開日2023-07-19
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of a bright green fluorescent protein (oxStayGold) in jellyfish Cytaeis uchidae from Biortus
To Be Published
7YRE
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Crystal structure of a bright green fluorescent protein (StayGold) with triple mutations (N137A, Q140S, Y187F) in jellyfish Cytaeis uchidae from Biortus
分子名称: 1,2-ETHANEDIOL, staygold(N137A,Q140S,Y187F)
著者Wu, J, Wang, F, Gui, W, Cheng, W, Yang, Y.
登録日2022-08-09
公開日2023-08-16
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a bright green fluorescent protein (StayGold) with triple mutations (N137A, Q140S, Y187F) in jellyfish Cytaeis uchidae from Biortus
To Be Published
8GYF
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Crystal structure of a bright green fluorescent protein (StayGold) with single mutation (K192Y) in jellyfish Cytaeis uchidae from Biortus
分子名称: 1,2-ETHANEDIOL, staygold(K192Y)
著者Wu, J, Wang, F, Gui, W, Cheng, W, Yang, Y.
登録日2022-09-22
公開日2023-10-04
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a bright green fluorescent protein (StayGold) with single mutation (K192Y) in jellyfish Cytaeis uchidae from Biortus
To Be Published
8I6G
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Crystal structure of the African swine fever virus DNA sliding clamp (native form)
分子名称: ASFV DNA sliding clamp
著者Wu, J, Gong, P.
登録日2023-01-28
公開日2023-06-07
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Crystal structure of African swine fever virus pE301R reveals a ring-shaped trimeric DNA sliding clamp.
J.Biol.Chem., 299, 2023
8I6H
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Crystal structure of the African swine fever virus DNA sliding clamp (selenomethionine form)
分子名称: ASFV DNA sliding clamp
著者Wu, J, Gong, P.
登録日2023-01-28
公開日2023-06-07
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.292 Å)
主引用文献Crystal structure of African swine fever virus pE301R reveals a ring-shaped trimeric DNA sliding clamp.
J.Biol.Chem., 299, 2023
6KR2
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Crystal structure of Dengue virus nonstructural protein NS5 (form 1)
分子名称: Genome polyprotein, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
著者Wu, J, Lu, G, Ye, H.Q, Gong, P.
登録日2019-08-20
公開日2020-04-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献A conformation-based intra-molecular initiation factor identified in the flavivirus RNA-dependent RNA polymerase.
Plos Pathog., 16, 2020
6KR3
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Crystal structure of Dengue virus nonstructural protein NS5 (form 2)
分子名称: GLYCEROL, Genome polyprotein, IODIDE ION, ...
著者Wu, J, Lu, G, Ye, H.Q, Gong, P.
登録日2019-08-20
公開日2020-04-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.931 Å)
主引用文献A conformation-based intra-molecular initiation factor identified in the flavivirus RNA-dependent RNA polymerase.
Plos Pathog., 16, 2020
7XD9
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BU of 7xd9 by Molmil
Crystal Structure of Dengue Virus serotype 2 (DENV2) Polymerase Elongation Complex (CTP Form)
分子名称: CYTIDINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
著者Wu, J, Wang, X, Gong, P.
登録日2022-03-26
公開日2022-12-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structural basis of transition from initiation to elongation in de novo viral RNA-dependent RNA polymerases.
Proc.Natl.Acad.Sci.USA, 120, 2023
7XD8
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Crystal Structure of Dengue Virus Serotype 2 (DENV2) Polymerase Elongation Complex (Native Form)
分子名称: GLYCEROL, NS5, RNA (30-mer), ...
著者Wu, J, Wang, X, Gong, P.
登録日2022-03-26
公開日2022-12-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural basis of transition from initiation to elongation in de novo viral RNA-dependent RNA polymerases.
Proc.Natl.Acad.Sci.USA, 120, 2023
7Y40
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Crystal structure of a bright green fluorescent protein (StayGold) in jellyfish Cytaeis uchidae from Biortus
分子名称: 1,2-ETHANEDIOL, staygold
著者Wu, J, Wang, F, Gui, W, Cheng, W, Yang, Y.
登録日2022-06-13
公開日2023-07-05
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of a bright green fluorescent protein (StayGold) in jellyfish Cytaeis uchidae from Biortus
To Be Published
7DLU
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Mechanosensitive channel MscS K180R mutant
分子名称: Mechanosensitive ion channel MscS
著者Wu, J, Ke, M.
登録日2020-11-30
公開日2022-03-02
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Mechanosensitive channel MscS K180R mutant
To Be Published
4W8P
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BU of 4w8p by Molmil
Crystal structure of RIAM TBS1 in complex with talin R7R8 domains
分子名称: 1,2-ETHANEDIOL, Amyloid beta A4 precursor protein-binding family B member 1-interacting protein, Talin-1
著者Chang, Y.C.E, Zhang, H, Wu, J.
登録日2014-08-25
公開日2014-12-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural and Mechanistic Insights into the Recruitment of Talin by RIAM in Integrin Signaling.
Structure, 22, 2014
3JBL
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BU of 3jbl by Molmil
Cryo-EM Structure of the Activated NAIP2/NLRC4 Inflammasome Reveals Nucleated Polymerization
分子名称: NLR family CARD domain-containing protein 4
著者Zhang, L, Chen, S, Ruan, J, Wu, J, Tong, A.B, Yin, Q, Li, Y, David, L, Lu, A, Wang, W.L, Marks, C, Ouyang, Q, Zhang, X, Mao, Y, Wu, H.
登録日2015-09-05
公開日2015-10-21
最終更新日2024-11-20
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization.
Science, 350, 2015
7LZ4
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Crystal structure of A211D mutant of Protein Kinase A RIa subunit, a Carney Complex mutation
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed
著者Del Rio, J, Wu, J, Taylor, S.S.
登録日2021-03-08
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (4.155 Å)
主引用文献Noncanonical protein kinase A activation by oligomerization of regulatory subunits as revealed by inherited Carney complex mutations.
Proc.Natl.Acad.Sci.USA, 118, 2021
2FEI
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BU of 2fei by Molmil
Solution structure of the second SH3 domain of Human CMS protein
分子名称: CD2-associated protein
著者Yao, B, Dai, H, Jiao, Y, Wu, J, Shi, Y.
登録日2005-12-15
公開日2006-12-05
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the second SH3 domain of human CMS and a newly identified binding site at the C-terminus of c-Cbl
Biochim.Biophys.Acta, 1774, 2007
5JI8
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Crystal structure of the BRD9 bromodomain and hit 1
分子名称: 2-amino-1,3-benzothiazole-6-carboxamide, Bromodomain-containing protein 9
著者Wang, N, Li, F, Bao, H, Li, J, Wu, J, Ruan, K.
登録日2016-04-22
公開日2016-06-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献NMR Fragment Screening Hit Induces Plasticity of BRD7/9 Bromodomains
Chembiochem, 17, 2016
5XUP
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Crystal structure of TRF1 and TERB1
分子名称: Telomere repeats-binding bouquet formation protein 1, Telomeric repeat-binding factor 1
著者Long, J, Huang, C, Wu, J, Lei, M.
登録日2017-06-24
公開日2017-11-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Telomeric TERB1-TRF1 interaction is crucial for male meiosis.
Nat. Struct. Mol. Biol., 24, 2017
4YE6
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The crystal structure of the intact human GlnRS
分子名称: Glutamine--tRNA ligase
著者Ognjenovic, J, Wu, J, Ling, J, Simonovic, M.
登録日2015-02-23
公開日2016-02-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The crystal structure of human GlnRS provides basis for the development of neurological disorders.
Nucleic Acids Res., 44, 2016

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