Crystal structure of TRF1 and TERB1

Summary for 5XUP

DescriptorTelomeric repeat-binding factor 1, Telomere repeats-binding bouquet formation protein 1 (3 entities in total)
Functional Keywordstelomere, meiosis, dna binding protein
Biological sourceHomo sapiens (Human)
Cellular locationNucleus P54274
Chromosome, telomere  Q8NA31
Total number of polymer chains4
Total molecular weight49307.02
Long, J.,Huang, C.,Wu, J.,Lei, M. (deposition date: 2017-06-24, release date: 2017-11-01, Last modification date: 2017-12-20)
Primary citation
Long, J.,Huang, C.,Chen, Y.,Zhang, Y.,Shi, S.,Wu, L.,Liu, Y.,Liu, C.,Wu, J.,Lei, M.
Telomeric TERB1-TRF1 interaction is crucial for male meiosis.
Nat. Struct. Mol. Biol., 24:1073-1080, 2017
PubMed: 29083416 (PDB entries with the same primary citation)
DOI: 10.1038/nsmb.3496
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2245 0.2% 4.4% 5.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-12-02