7V1A
| Stapled TBS peptide from RIAM bound to talin R7R8 domains | 分子名称: | 1,2-ETHANEDIOL, ASP-ILE-ASP-GLN-MET-PHE-SER-THR-LEU-LEU-GLY-GLU-MK8-ASP-LEU-LEU-MK8-GLN-SER, Talin-1 | 著者 | Zhang, P, Gao, T, Wu, J. | 登録日 | 2022-05-11 | 公開日 | 2023-06-14 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.845 Å) | 主引用文献 | Inhibition of talin-induced integrin activation by a double-hit stapled peptide. Structure, 31, 2023
|
|
8HPP
| |
5VHP
| Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle | 分子名称: | 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit 10B, ... | 著者 | Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. | 登録日 | 2017-04-13 | 公開日 | 2017-08-23 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (7.9 Å) | 主引用文献 | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle. Mol. Cell, 67, 2017
|
|
4ZRU
| X-ray crystal structure of Lymnaea stagnalis acetylcholine binding protein (Ls-AChBP) in complex with 3-[2-[(2S)-pyrrolidin-2-yl]ethynyl]pyridine (TI-5180) | 分子名称: | 3-[(2S)-pyrrolidin-2-ylethynyl]pyridine, Acetylcholine-binding protein, PHOSPHATE ION | 著者 | Bobango, J, Sankaran, B, Park, J.F, Wu, J, Talley, T.T. | 登録日 | 2015-05-12 | 公開日 | 2015-05-27 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Comparisons of Binding Affinities for Neuronal Nicotinic Receptors (NNRs) and AChBPs, and Structural Features of a High-Affinity, Non-selective NNR Ligand-AChBP Co-crystal Structure To be Published
|
|
7Y11
| Crystal structure of AtSFH5-Sec14 in complex with egg PA | 分子名称: | (2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate, CHLORIDE ION, NICKEL (II) ION, ... | 著者 | Lu, Y.Q, Wang, X.Q, Luo, Z.P, Wu, J.W. | 登録日 | 2022-06-06 | 公開日 | 2023-04-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Arabidopsis Sec14 proteins (SFH5 and SFH7) mediate interorganelle transport of phosphatidic acid and regulate chloroplast development. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
7Y10
| Crystal structure of AtSFH5-Sec14 in complex with DPPA | 分子名称: | 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE, NICKEL (II) ION, Phosphatidylinositol/phosphatidylcholine transfer protein SFH5 | 著者 | Lu, Y.Q, Wang, X.Q, Luo, Z.P, Wu, J.W. | 登録日 | 2022-06-06 | 公開日 | 2023-05-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Arabidopsis Sec14 proteins (SFH5 and SFH7) mediate interorganelle transport of phosphatidic acid and regulate chloroplast development. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
4NTT
| |
4NTS
| |
7WTC
| Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the ground state | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ACETYL COENZYME *A, Pyruvate carboxylase, ... | 著者 | Chai, P, Lan, P, Wu, J, Lei, M. | 登録日 | 2022-02-04 | 公開日 | 2022-11-09 | 最終更新日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
|
|
7WTB
| Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ACETYL COENZYME *A, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Chai, P, Lan, P, Wu, J, Lei, M. | 登録日 | 2022-02-04 | 公開日 | 2022-11-09 | 最終更新日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
|
|
5X0M
| Structure of a eukaryotic voltage-gated sodium channel at near atomic resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Sodium channel protein, ... | 著者 | Shen, H, Zhou, Q, Pan, X, Li, Z, Wu, J, Yan, N. | 登録日 | 2017-01-21 | 公開日 | 2017-03-08 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure of a eukaryotic voltage-gated sodium channel at near-atomic resolution. Science, 355, 2017
|
|
5YYZ
| Crystal structure of the MEK1 FHA domain in complex with the HOP1 pThr318 peptide. | 分子名称: | Meiosis-specific protein HOP1, Meiosis-specific serine/threonine-protein kinase MEK1 | 著者 | Xie, C, Li, F, Jiang, Y, Wu, J, Shi, Y. | 登録日 | 2017-12-11 | 公開日 | 2018-10-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.798 Å) | 主引用文献 | Structural insights into the recognition of phosphorylated Hop1 by Mek1 Acta Crystallogr D Struct Biol, 74, 2018
|
|
5Z1F
| |
5YWD
| |
5YYX
| Crystal Structure of the MEK1 FHA domain | 分子名称: | Meiosis-specific serine/threonine-protein kinase MEK1 | 著者 | Xie, C, Li, F, Jiang, Y, Wu, J, Shi, Y. | 登録日 | 2017-12-11 | 公開日 | 2018-10-10 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.684 Å) | 主引用文献 | Structural insights into the recognition of phosphorylated Hop1 by Mek1 Acta Crystallogr D Struct Biol, 74, 2018
|
|
5YW7
| |
8TK2
| HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE (VHR) complexed with 2-((2,4-difluorobenzyl)amino)-2-oxoacetic acid | 分子名称: | DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, Dual specificity protein phosphatase 3, ... | 著者 | Aleshin, A.E, Wu, J, Lambert, L.J, Cosford, N.D.P, Tautz, L. | 登録日 | 2023-07-25 | 公開日 | 2024-08-14 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE (VHR) binding 2-((2,4-difluorobenzyl)amino)-2-oxoacetic acid To Be Published
|
|
7WTD
| Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the intermediate state 1 | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, COENZYME A, Pyruvate carboxylase, ... | 著者 | Chai, P, Lan, P, Wu, J, Lei, M. | 登録日 | 2022-02-04 | 公開日 | 2022-11-09 | 最終更新日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
|
|
7WTE
| Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the intermediate state 2 | 分子名称: | ACETYL COENZYME *A, ADENOSINE-5'-TRIPHOSPHATE, Pyruvate carboxylase, ... | 著者 | Chai, P, Lan, P, Wu, J, Lei, M. | 登録日 | 2022-02-04 | 公開日 | 2022-11-09 | 最終更新日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
|
|
7WTA
| Cryo-EM structure of human pyruvate carboxylase in apo state | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Pyruvate carboxylase, mitochondrial | 著者 | Chai, P, Lan, P, Wu, J, Lei, M. | 登録日 | 2022-02-04 | 公開日 | 2022-11-09 | 最終更新日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
|
|
2QZQ
| |
7VIO
| Crystal structure of recombinant horse spleen apo-R168H/L169C-Fr | 分子名称: | CADMIUM ION, Ferritin light chain, GLYCEROL, ... | 著者 | Lu, C, Peng, X, Maity, B, Ito, N, Abe, S, Wu, J, Ueno, T, Lu, D. | 登録日 | 2021-09-27 | 公開日 | 2022-06-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Design of a gold clustering site in an engineered apo-ferritin cage. Commun Chem, 5, 2022
|
|