4ZRU

X-ray crystal structure of Lymnaea stagnalis acetylcholine binding protein (Ls-AChBP) in complex with 3-[2-[(2S)-pyrrolidin-2-yl]ethynyl]pyridine (TI-5180)

Summary for 4ZRU

• Entry DOI: 10.2210/pdb4zru/pdb
• Descriptor: Acetylcholine-binding protein, PHOSPHATE ION, 3-[(2S)-pyrrolidin-2-ylethynyl]pyridine, ... (4 entities in total)
• Functional Keywords: nicotinic, acetylcholine, ls-achbp, acetylcholine binding protein
• Biological source: Lymnaea stagnalis (Great pond snail)
• Cellular location: Secreted: P58154
• Total number of polymer chains: 10
• Total formula weight: 251266.93

Authors

Bobango, J.,Sankaran, B.,Park, J.F.,Wu, J.,Talley, T.T. (deposition date: 2015-05-12, release date: 2015-05-27, Last modification date: 2023-09-27)

• Primary citation: Talley, T.T.; Comparisons of Binding Affinities for Neuronal Nicotinic Receptors (NNRs) and AChBPs, and Structural Features of a High-Affinity, Non-selective NNR Ligand-AChBP Co-crystal Structure; To be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)