4ZRU
X-ray crystal structure of Lymnaea stagnalis acetylcholine binding protein (Ls-AChBP) in complex with 3-[2-[(2S)-pyrrolidin-2-yl]ethynyl]pyridine (TI-5180)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Acetylcholine-binding protein | polymer | 218 | 24859.5 | 10 | UniProt (P58154) | Lymnaea stagnalis (Great pond snail) | AchBP |
| 2 | AA, BA, K, L, N... (I, A, B, C, D...) | PHOSPHATE ION | non-polymer | 95.0 | 10 | Chemie (PO4) PubChem (1061) | |||
| 3 | CA, DA, M, O, Q... (I, J, A, B, C...) | 3-[(2S)-pyrrolidin-2-ylethynyl]pyridine | non-polymer | 172.2 | 10 | Chemie (TI9) PubChem (9942264) PubChem (9942265) PubChem (21964025) | |||
| 4 | EA, FA, GA, HA, IA... (A, B, C, D, E...) | water | water | 18.0 | 1550 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J: 1 - 210 (UniProt: P58154)
| PDB | External Database | Details |
|---|---|---|
| Asp -7 | - | expression tag |
| Tyr -6 | - | expression tag |
| Lys -5 | - | expression tag |
| Asp -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Asp -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Lys 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 248595.0 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 2672.0 | |
| All* | Total formula weight | 251266.9 |
