Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 44 件
7DBD
DownloadVisualize
BU of 7dbd by Molmil
444 in complex with tubulin
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
著者Wu, C.Y, Wang, Y.X.
登録日2020-10-19
公開日2021-10-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.094 Å)
主引用文献444 in complex with tubulin
To Be Published
7DBC
DownloadVisualize
BU of 7dbc by Molmil
PRA in complex with tubulin
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
著者Wu, C.Y, Wang, Y.X.
登録日2020-10-19
公開日2021-10-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献PRA in complex with tubulin
To Be Published
7DBB
DownloadVisualize
BU of 7dbb by Molmil
SSE in complex with tubulin
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5-phenyl-3-(3,4,5-trimethoxyphenyl)-3,4-dihydropyrazole-2-carbothioamide, CALCIUM ION, ...
著者Wu, C.Y, Wang, Y.X.
登録日2020-10-19
公開日2021-10-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.805 Å)
主引用文献SSE in complex with tubulin
To Be Published
7DB9
DownloadVisualize
BU of 7db9 by Molmil
IC1 in complex with tubulin
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-[(2,4,6-TRIMETHOXY-PHENYL)-METHYLENE]-INDOLIN-2-ONE, CALCIUM ION, ...
著者Wu, C.Y, Wang, Y.X.
登録日2020-10-19
公開日2021-10-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.845 Å)
主引用文献IC1 in complex with tubulin
To Be Published
7DBA
DownloadVisualize
BU of 7dba by Molmil
RYX in complex with tubulin
分子名称: 2-(1-methylindol-4-yl)-7-(3,4,5-trimethoxyphenyl)-1~{H}-benzimidazole, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
著者Wu, C.Y, Wang, Y.X.
登録日2020-10-19
公開日2021-10-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.461 Å)
主引用文献RYX in complex with tubulin
To Be Published
8ZB8
DownloadVisualize
BU of 8zb8 by Molmil
Crystal structure of T2R-TTL-DPP21 complex
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Detyrosinated tubulin alpha-1B chain, ...
著者Wu, C.Y, Chen, J.J.
登録日2024-04-26
公開日2024-06-26
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Crystal structure of T2R-TTL-DPP21 complex
To Be Published
8YTX
DownloadVisualize
BU of 8ytx by Molmil
Tubulin-RB3-TTL in complex with compound SI9
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-chloranyl-~{N}-(4-methoxyphenyl)-~{N}-methyl-thieno[2,3-d]pyrimidin-4-amine, CALCIUM ION, ...
著者Wu, C.Y, Wang, Y.X.
登録日2024-03-26
公開日2024-06-05
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Tubulin-RB3-TTL in complex with compound SI9
To Be Published
8YUA
DownloadVisualize
BU of 8yua by Molmil
Tubulin-RB3-TTL in complex with compound SI10
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-chloranyl-~{N}-(4-methoxyphenyl)-~{N}-methyl-thieno[3,2-d]pyrimidin-4-amine, CALCIUM ION, ...
著者Wu, C.Y, Wang, Y.X.
登録日2024-03-27
公開日2024-06-05
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献The complex structure of tubulin-RB3-TTL in complex with compound SI10
To Be Published
8YU9
DownloadVisualize
BU of 8yu9 by Molmil
Tubulin-RB3-TTL in complex with compound SI10
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(2-chloranylthieno[3,2-d]pyrimidin-4-yl)-7-methoxy-1,3-dihydroquinoxalin-2-one, CALCIUM ION, ...
著者Wu, C.Y, Wang, Y.X.
登録日2024-03-27
公開日2024-06-05
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献The crystal structure of tubulin-RB3-TTL in complex with compound AB10
To Be Published
6K80
DownloadVisualize
BU of 6k80 by Molmil
Crystal Structure of Drosophila melanogaster Dopamine N-Acetyltransferase in Complex with CoA and Tryptophol
分子名称: 2-(1H-indol-3-yl)ethanol, ACETYL COENZYME *A, Dopamine N-acetyltransferase
著者Wu, C.Y, Hu, I.C, Yang, Y.C, Cheng, H.C, Lyu, P.C.
登録日2019-06-11
公開日2020-06-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献An essential role of acetyl coenzyme A in the catalytic cycle of insect arylalkylamine N-acetyltransferase.
Commun Biol, 3, 2020
7XBI
DownloadVisualize
BU of 7xbi by Molmil
The crystal structure of human TrkA kinase bound to the inhibitor
分子名称: 4-[[2-fluoranyl-5-(trifluoromethyl)phenyl]carbamoylamino]-~{N}-[3-(1-methylpyrazol-4-yl)-1~{H}-indazol-5-yl]-2-(trifluoromethyl)benzamide, CHLORIDE ION, High affinity nerve growth factor receptor
著者Wu, C.Y, Wang, G, Ouyang, L.
登録日2022-03-21
公開日2023-03-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献The crystal structure of human TrkA kinase bound to the inhibitor
To be published
7CNO
DownloadVisualize
BU of 7cno by Molmil
Phomopsin A in complex with tubulin
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ...
著者Wu, C.Y, Wang, Y.X.
登録日2020-08-02
公開日2021-08-04
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The high-resolution X-ray structure of vinca-domain inhibitors of microtubules provides a rational approach for drug design.
Febs Lett., 595, 2021
1FSW
DownloadVisualize
BU of 1fsw by Molmil
AMPC BETA-LACTAMASE FROM E. COLI COMPLEXED WITH INHIBITOR CEPHALOTHINBORONIC ACID
分子名称: CEPHALOSPORINASE, N-2-THIOPHEN-2-YL-ACETAMIDE BORONIC ACID, PHOSPHATE ION
著者Caselli, E, Powers, R.A, Blaszczak, L.C, Wu, C.Y, Prati, F, Shoichet, B.K.
登録日2000-09-11
公開日2001-03-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Energetic, structural, and antimicrobial analyses of beta-lactam side chain recognition by beta-lactamases.
Chem.Biol., 8, 2001
1FSY
DownloadVisualize
BU of 1fsy by Molmil
AMPC BETA-LACTAMASE FROM E. COLI COMPLEXED WITH INHIBITOR CLOXACILLINBORONIC ACID
分子名称: CEPHALOSPORINASE, N-[5-METHYL-3-O-TOLYL-ISOXAZOLE-4-CARBOXYLIC ACID AMIDE] BORONIC ACID, PHOSPHATE ION
著者Caselli, E, Powers, R.A, Blasczcak, L.C, Wu, C.Y, Prati, F, Shoichet, B.K.
登録日2000-09-11
公開日2001-03-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Energetic, structural, and antimicrobial analyses of beta-lactam side chain recognition by beta-lactamases.
Chem.Biol., 8, 2001
8HY7
DownloadVisualize
BU of 8hy7 by Molmil
EGFR kinase domain mutant "TMLR" with compound 28f
分子名称: Epidermal growth factor receptor, ~{N}-[3-[[6-fluoranyl-2-[[4-(4-methylpiperazin-1-yl)phenyl]amino]quinazolin-4-yl]amino]phenyl]prop-2-enamide
著者Wang, Y.X, Wu, C.Y.
登録日2023-01-06
公開日2023-08-23
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献The crystal structure of EGFR kinase domain(T790M/L858R) in complex with compound 28f
To Be Published
7CEM
DownloadVisualize
BU of 7cem by Molmil
Crystal Structure of YbeA CP74 W7F
分子名称: Ribosomal RNA large subunit methyltransferase H,Ribosomal RNA large subunit methyltransferase H
著者Liu, C.Y, Wu, C.Y, Lai, C.H, Hsu, S.T.D, Lyu, P.C.
登録日2020-06-23
公開日2021-06-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4251 Å)
主引用文献Crystal Structure of YbeA CP74 W7F
To Be Published
5J6A
DownloadVisualize
BU of 5j6a by Molmil
Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PS46
分子名称: (3S)-3-amino-4-[4-({2-[(2,4-dihydroxyphenyl)sulfonyl]-2H-isoindol-5-yl}amino)piperidin-1-yl]-4-oxobutanamide, [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial
著者Gui, W.J, Tso, S.C, Chuang, J.L, Wu, C.Y, Qi, X, Wynn, R.M, Chuang, D.T.
登録日2016-04-04
公開日2017-01-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.045 Å)
主引用文献Development of Dihydroxyphenyl Sulfonylisoindoline Derivatives as Liver-Targeting Pyruvate Dehydrogenase Kinase Inhibitors.
J. Med. Chem., 60, 2017
4MPN
DownloadVisualize
BU of 4mpn by Molmil
Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PS10
分子名称: 2-[(2,4-dihydroxyphenyl)sulfonyl]-2,3-dihydro-1H-isoindole-4,6-diol, L(+)-TARTARIC ACID, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, ...
著者Gui, W.J, Tso, S.C, Chuang, J.L, Wu, C.Y, Qi, X, Tambar, U.K, Wynn, R.M, Chuang, D.T.
登録日2013-09-13
公開日2014-01-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.752 Å)
主引用文献Structure-guided Development of Specific Pyruvate Dehydrogenase Kinase Inhibitors Targeting the ATP-binding Pocket.
J.Biol.Chem., 289, 2014
4MP2
DownloadVisualize
BU of 4mp2 by Molmil
Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PA1
分子名称: (5-bromo-2,4-dihydroxyphenyl)(1,3-dihydro-2H-isoindol-2-yl)methanone, L(+)-TARTARIC ACID, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, ...
著者Gui, W.J, Tso, S.C, Chuang, J.L, Wu, C.Y, Qi, X, Tambar, U.K, Wynn, R.M, Chuang, D.T.
登録日2013-09-12
公開日2014-01-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.751 Å)
主引用文献Structure-guided Development of Specific Pyruvate Dehydrogenase Kinase Inhibitors Targeting the ATP-binding Pocket.
J.Biol.Chem., 289, 2014
4MP7
DownloadVisualize
BU of 4mp7 by Molmil
Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PA7
分子名称: 4-(1,3-dihydro-2H-isoindol-2-ylcarbonyl)benzene-1,3-diol, L(+)-TARTARIC ACID, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, ...
著者Gui, W.J, Tso, S.C, Chuang, J.L, Wu, C.Y, Qi, X, Tambar, U.K, Wynn, R.M, Chuang, D.T.
登録日2013-09-12
公開日2014-01-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure-guided Development of Specific Pyruvate Dehydrogenase Kinase Inhibitors Targeting the ATP-binding Pocket.
J.Biol.Chem., 289, 2014
4MPE
DownloadVisualize
BU of 4mpe by Molmil
Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PS8
分子名称: 4-[(5-hydroxy-1,3-dihydro-2H-isoindol-2-yl)sulfonyl]benzene-1,3-diol, L(+)-TARTARIC ACID, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, ...
著者Gui, W.J, Tso, S.C, Chuang, J.L, Wu, C.Y, Qi, X, Tambar, U.K, Wynn, R.M, Chuang, D.T.
登録日2013-09-12
公開日2014-01-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.953 Å)
主引用文献Structure-guided Development of Specific Pyruvate Dehydrogenase Kinase Inhibitors Targeting the ATP-binding Pocket.
J.Biol.Chem., 289, 2014
4MPC
DownloadVisualize
BU of 4mpc by Molmil
Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PS2
分子名称: 4-(isoindolin-2-ylsulfonyl)benzene-1,3-diol, L(+)-TARTARIC ACID, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, ...
著者Gui, W.J, Tso, S.C, Chuang, J.L, Wu, C.Y, Qi, X, Tambar, U.K, Wynn, R.M, Chuang, D.T.
登録日2013-09-12
公開日2014-01-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.699 Å)
主引用文献Structure-guided Development of Specific Pyruvate Dehydrogenase Kinase Inhibitors Targeting the ATP-binding Pocket.
J.Biol.Chem., 289, 2014
5J71
DownloadVisualize
BU of 5j71 by Molmil
Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PS35
分子名称: 4-({5-[(piperidin-4-yl)amino]-1,3-dihydro-2H-isoindol-2-yl}sulfonyl)benzene-1,3-diol, L(+)-TARTARIC ACID, [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, ...
著者Gui, W.J, Tso, S.C, Chuang, J.L, Wu, C.Y, Qi, X, Wynn, R.M, Chuang, D.T.
登録日2016-04-05
公開日2017-01-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Development of Dihydroxyphenyl Sulfonylisoindoline Derivatives as Liver-Targeting Pyruvate Dehydrogenase Kinase Inhibitors.
J. Med. Chem., 60, 2017
8I0B
DownloadVisualize
BU of 8i0b by Molmil
The crystal structure of human glutamate receptor 2 in complex with LT-102
分子名称: 8-[4-(2-fluorophenyl)phenyl]-3,4-dihydro-1,2$l^{6},3-benzoxathiazine 2,2-dioxide, CHLORIDE ION, Glutamate receptor 2,Isoform Flip of Glutamate receptor 2, ...
著者Qi, X.Y, Wu, C.Y.
登録日2023-01-10
公開日2024-02-07
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Structure of the human GluA2 LBD in complex with LT-102
To Be Published
5GIF
DownloadVisualize
BU of 5gif by Molmil
Crystal Structure of Drosophila melanogaster E47D Dopamine N-Acetyltransferase in Binary Complex with Acetyl-CoA
分子名称: (4S,5S)-1,2-DITHIANE-4,5-DIOL, ACETYL COENZYME *A, Dopamine N-acetyltransferase
著者Yang, Y.C, Wu, C.Y, Cheng, H.C, Lyu, P.C.
登録日2016-06-23
公開日2017-07-05
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal Structure of Drosophila melanogaster E47D Dopamine N-Acetyltransferase in Binary Complex with Acetyl-CoA
To Be Published

 

12>

222624

件を2024-07-17に公開中

PDB statisticsPDBj update infoContact PDBjnumon