7CNO

Phomopsin A in complex with tubulin

Summary for 7CNO

Entry DOI	10.2210/pdb7cno/pdb
Descriptor	Tubulin alpha-1B chain, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Phomopsin A, ... (13 entities in total)
Functional Keywords	phomopsin a, tubulin, protein-drug complex, cell cycle
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	6
Total formula weight	266331.21
Authors	Wu, C.Y.,Wang, Y.X. (deposition date: 2020-08-02, release date: 2021-08-04, Last modification date: 2023-11-29)
Primary citation	Chengyong, W.,Jinghong, X.,Yanyan, W.,Qing-Jie, X.,Lingling, M.,Yuyan, L.,Hai, C.,Qian, L.,Quan, Z.,Bo, S.,Yuxi, W. The high-resolution X-ray structure of vinca-domain inhibitors of microtubules provides a rational approach for drug design. Febs Lett., 595:195-205, 2021 Cited by PubMed: 33220079 DOI: 10.1002/1873-3468.14003 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation