1Z0W
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![BU of 1z0w by Molmil](/molmil-images/mine/1z0w) | Crystal Structure of A. fulgidus Lon proteolytic domain at 1.2A resolution | Descriptor: | CALCIUM ION, Putative protease La homolog type | Authors: | Botos, I, Melnikov, E.E, Cherry, S, Kozlov, S, Makhovskaya, O.V, Tropea, J.E, Gustchina, A, Rotanova, T.V, Wlodawer, A. | Deposit date: | 2005-03-02 | Release date: | 2005-08-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Atomic-resolution Crystal Structure of the Proteolytic Domain of Archaeoglobus fulgidus Lon Reveals the Conformational Variability in the Active Sites of Lon Proteases J.Mol.Biol., 351, 2005
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1BPT
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![BU of 1bpt by Molmil](/molmil-images/mine/1bpt) | CREVICE-FORMING MUTANTS OF BPTI: CRYSTAL STRUCTURES OF F22A, Y23A, N43G, AND F45A | Descriptor: | BOVINE PANCREATIC TRYPSIN INHIBITOR, PHOSPHATE ION | Authors: | Housset, D, Wlodawer, A, Tao, F, Fuchs, J, Woodward, C. | Deposit date: | 1991-12-11 | Release date: | 1993-01-15 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crevice-forming mutants in the rigid core of bovine pancreatic trypsin inhibitor: crystal structures of F22A, Y23A, N43G, and F45A. Protein Sci., 2, 1993
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1BTI
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![BU of 1bti by Molmil](/molmil-images/mine/1bti) | CREVICE-FORMING MUTANTS IN THE RIGID CORE OF BOVINE PANCREATIC TRYPSIN INHIBITOR: CRYSTAL STRUCTURES OF F22A, Y23A, N43G, AND F45A | Descriptor: | BOVINE PANCREATIC TRYPSIN INHIBITOR | Authors: | Housset, D, Tao, F, Kim, K.-S, Fuchs, J, Woodward, C, Wlodawer, A. | Deposit date: | 1991-07-11 | Release date: | 1993-10-31 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crevice-forming mutants in the rigid core of bovine pancreatic trypsin inhibitor: crystal structures of F22A, Y23A, N43G, and F45A. Protein Sci., 2, 1993
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1Z0B
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![BU of 1z0b by Molmil](/molmil-images/mine/1z0b) | Crystal Structure of A. fulgidus Lon proteolytic domain E506A mutant | Descriptor: | CALCIUM ION, Putative protease La homolog type | Authors: | Botos, I, Melnikov, E.E, Cherry, S, Kozlov, S, Makhovskaya, O.V, Tropea, J.E, Gustchina, A, Rotanova, T.V, Wlodawer, A. | Deposit date: | 2005-03-01 | Release date: | 2005-08-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Atomic-resolution Crystal Structure of the Proteolytic Domain of Archaeoglobus fulgidus Lon Reveals the Conformational Variability in the Active Sites of Lon Proteases J.Mol.Biol., 351, 2005
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2B7F
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![BU of 2b7f by Molmil](/molmil-images/mine/2b7f) | Crystal structure of human T-cell leukemia virus protease, a novel target for anti-cancer design | Descriptor: | (ACE)APQV(STA)VMHP peptide, HTLV protease, PHOSPHATE ION | Authors: | Li, M, Laco, G.S, Jaskolski, M, Rozycki, J, Alexandratos, J, Wlodawer, A, Gustchina, A. | Deposit date: | 2005-10-04 | Release date: | 2005-12-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of human T cell leukemia virus protease, a novel target for anticancer drug design Proc.Natl.Acad.Sci.Usa, 102, 2005
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4YEN
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![BU of 4yen by Molmil](/molmil-images/mine/4yen) | Room temperature X-ray diffraction studies of cisplatin binding to HEWL in DMSO media after 14 months of crystal storage - new refinement | Descriptor: | CHLORIDE ION, DIMETHYL SULFOXIDE, Lysozyme C, ... | Authors: | Shabalin, I.G, Dauter, Z, Jaskolski, M, Minor, W, Wlodawer, A. | Deposit date: | 2015-02-24 | Release date: | 2015-03-04 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystallography and chemistry should always go together: a cautionary tale of protein complexes with cisplatin and carboplatin. Acta Crystallogr.,Sect.D, 71, 2015
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2EMN
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![BU of 2emn by Molmil](/molmil-images/mine/2emn) | |
2EMD
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![BU of 2emd by Molmil](/molmil-images/mine/2emd) | |
2EMO
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![BU of 2emo by Molmil](/molmil-images/mine/2emo) | |
2ANE
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![BU of 2ane by Molmil](/molmil-images/mine/2ane) | Crystal structure of N-terminal domain of E.Coli Lon Protease | Descriptor: | ATP-dependent protease La | Authors: | Li, M, Rasulova, F, Melnikov, E.E, Rotanova, T.V, Gustchina, A, Maurizi, M.R, Wlodawer, A. | Deposit date: | 2005-08-11 | Release date: | 2005-11-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Crystal structure of the N-terminal domain of E. coli Lon protease. Protein Sci., 14, 2005
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1JSL
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![BU of 1jsl by Molmil](/molmil-images/mine/1jsl) | Crystal structure of Erwinia chrysanthemi L-asparaginase complexed with 6-HYDROXY-D-NORLEUCINE | Descriptor: | 6-HYDROXY-D-NORLEUCINE, GLYCEROL, L-asparaginase, ... | Authors: | Aghaiypour, K, Wlodawer, A, Lubkowski, J. | Deposit date: | 2001-08-17 | Release date: | 2002-01-09 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Do bacterial L-asparaginases utilize a catalytic triad Thr-Tyr-Glu? Biochim.Biophys.Acta, 1550, 2001
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2ILK
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![BU of 2ilk by Molmil](/molmil-images/mine/2ilk) | |
1ZPA
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![BU of 1zpa by Molmil](/molmil-images/mine/1zpa) | HIV Protease with Scripps AB-3 Inhibitor | Descriptor: | Pol polyprotein, TERT-BUTYL 4-[({[1-((1S,2R)-1-BENZYL-2-HYDROXY-3-{ISOBUTYL[(4-METHOXYPHENYL)SULFONYL]AMINO}PROPYL)-1H-1,2,3-TRIAZOL-4-YL]METHYL}AMINO)CARBONYL]BENZYLCARBAMATE | Authors: | Brik, A, Alexandratos, J, Lin, Y.C, Elder, J.H, Olson, A.J, Wlodawer, A, Goodsell, D.S, Wong, C.H. | Deposit date: | 2005-05-16 | Release date: | 2005-05-31 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | 1,2,3-triazole as a peptide surrogate in the rapid synthesis of HIV-1 protease inhibitors Chembiochem, 6, 2005
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1JSR
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![BU of 1jsr by Molmil](/molmil-images/mine/1jsr) | CRYSTAL STRUCTURE OF ERWINIA CHRYSANTHEMI L-ASPARAGINASE COMPLEXED WITH 6-HYDROXY-L-NORLEUCINE | Descriptor: | 6-HYDROXY-L-NORLEUCINE, GLYCEROL, L-asparaginase, ... | Authors: | Aghaiypour, K, Wlodawer, A, Lubkowski, J. | Deposit date: | 2001-08-17 | Release date: | 2002-01-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Do bacterial L-asparaginases utilize a catalytic triad Thr-Tyr-Glu? Biochim.Biophys.Acta, 1550, 2001
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3MAC
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![BU of 3mac by Molmil](/molmil-images/mine/3mac) | crystal structure of GP41-derived protein complexed with fab 8062 | Descriptor: | Fab8062, Transmembrane glycoprotein | Authors: | Li, M, Gustchina, E, Louis, J, Gustchina, A, Wlodawer, A, Clore, M. | Deposit date: | 2010-03-23 | Release date: | 2010-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Basis of HIV-1 Neutralization by Affinity Matured Fabs Directed against the Internal Trimeric Coiled-Coil of gp41. Plos Pathog., 6, 2010
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3OG4
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![BU of 3og4 by Molmil](/molmil-images/mine/3og4) | The crystal structure of human interferon lambda 1 complexed with its high affinity receptor in space group P21212 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin 28 receptor, alpha (Interferon, ... | Authors: | Miknis, Z.J, Magracheva, E, Lei, W, Zdanov, A, Kotenko, S.V, Wlodawer, A. | Deposit date: | 2010-08-16 | Release date: | 2010-10-20 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Crystal structure of the complex of human interferon-lambda1 with its high affinity receptor interferon-lambdaR1. J.Mol.Biol., 404, 2010
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3OG6
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![BU of 3og6 by Molmil](/molmil-images/mine/3og6) | The crystal structure of human interferon lambda 1 complexed with its high affinity receptor in space group P212121 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Interleukin 28 receptor, ... | Authors: | Miknis, Z.J, Magracheva, E, Lei, W, Zdanov, A, Kotenko, S.V, Wlodawer, A. | Deposit date: | 2010-08-16 | Release date: | 2010-10-20 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.097 Å) | Cite: | Crystal structure of the complex of human interferon-lambda1 with its high affinity receptor interferon-lambdaR1. J.Mol.Biol., 404, 2010
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3MA9
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![BU of 3ma9 by Molmil](/molmil-images/mine/3ma9) | Crystal structure of gp41 derived protein complexed with fab 8066 | Descriptor: | Fab8066 FAB ANTIBODY FRAGMENT, Heavy Chain, Light Chain, ... | Authors: | Li, M, Gustchina, E, Louis, J, Gustchina, A, Wlodawer, A, Clore, M. | Deposit date: | 2010-03-23 | Release date: | 2010-12-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural Basis of HIV-1 Neutralization by Affinity Matured Fabs Directed against the Internal Trimeric Coiled-Coil of gp41. Plos Pathog., 6, 2010
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1L6S
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![BU of 1l6s by Molmil](/molmil-images/mine/1l6s) | Crystal Structure of Porphobilinogen Synthase Complexed with the Inhibitor 4,7-Dioxosebacic Acid | Descriptor: | 4,7-DIOXOSEBACIC ACID, MAGNESIUM ION, PORPHOBILINOGEN SYNTHASE, ... | Authors: | Jaffe, E.K, Kervinen, J, Martins, J, Stauffer, F, Neier, R, Wlodawer, A, Zdanov, A. | Deposit date: | 2002-03-13 | Release date: | 2002-04-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Species-Specific Inhibition of Porphobilinogen Synthase by 4-Oxosebacic Acid J.Biol.Chem., 277, 2002
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1L6Y
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![BU of 1l6y by Molmil](/molmil-images/mine/1l6y) | Crystal Structure of Porphobilinogen Synthase Complexed with the Inhibitor 4-Oxosebacic Acid | Descriptor: | 4-OXODECANEDIOIC ACID, GLYCEROL, MAGNESIUM ION, ... | Authors: | Jaffe, E.K, Kervinen, J, Martins, J, Stauffer, F, Neier, R, Wlodawer, A, Zdanov, A. | Deposit date: | 2002-03-14 | Release date: | 2002-04-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Species-Specific Inhibition of Porphobilinogen Synthase by 4-Oxosebacic Acid J.Biol.Chem., 277, 2002
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4KHT
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![BU of 4kht by Molmil](/molmil-images/mine/4kht) | Triple helix bundle of GP41 complexed with fab 8066 | Descriptor: | 8066 heavy chain, 8066 light chain, Gp41 helix | Authors: | Li, M, Gustchina, A, Wlodawer, A. | Deposit date: | 2013-05-01 | Release date: | 2014-03-12 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.817 Å) | Cite: | Complexes of neutralizing and non-neutralizing affinity matured Fabs with a mimetic of the internal trimeric coiled-coil of HIV-1 gp41. Plos One, 8, 2013
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3NR6
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![BU of 3nr6 by Molmil](/molmil-images/mine/3nr6) | Crystal structure of xenotropic murine leukemia virus-related virus (XMRV) protease | Descriptor: | PHOSPHATE ION, POTASSIUM ION, Protease p14 | Authors: | Lubkowski, J, Li, M, Gustchina, A, Zhou, D, Dauter, Z, Wlodawer, A. | Deposit date: | 2010-06-30 | Release date: | 2011-02-02 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Crystal structure of XMRV protease differs from the structures of other retropepsins. Nat.Struct.Mol.Biol., 18, 2011
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4KHX
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![BU of 4khx by Molmil](/molmil-images/mine/4khx) | |
3QS1
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![BU of 3qs1 by Molmil](/molmil-images/mine/3qs1) | Crystal structure of KNI-10006 complex of Plasmepsin I (PMI) from Plasmodium falciparum | Descriptor: | (4R)-3-[(2S,3S)-3-{[(2,6-dimethylphenoxy)acetyl]amino}-2-hydroxy-4-phenylbutanoyl]-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide, GLYCEROL, Plasmepsin-1 | Authors: | Bhaumik, P, Gustchina, A, Wlodawer, A. | Deposit date: | 2011-02-19 | Release date: | 2011-05-11 | Last modified: | 2012-12-12 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal structures of the free and inhibited forms of plasmepsin I (PMI) from Plasmodium falciparum. J.Struct.Biol., 175, 2011
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4E2U
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![BU of 4e2u by Molmil](/molmil-images/mine/4e2u) | Crystal Structures of RadAmin intein from Pyrococcus horikoshii | Descriptor: | Pho radA intein | Authors: | Oeemig, J.S, Zhou, D, Kajander, T, Wlodawer, A, Iwai, H. | Deposit date: | 2012-03-09 | Release date: | 2012-05-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.582 Å) | Cite: | NMR and Crystal Structures of the Pyrococcus horikoshii RadA Intein Guide a Strategy for Engineering a Highly Efficient and Promiscuous Intein. J.Mol.Biol., 421, 2012
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