1L6Y

Crystal Structure of Porphobilinogen Synthase Complexed with the Inhibitor 4-Oxosebacic Acid

Summary for 1L6Y

• Entry DOI: 10.2210/pdb1l6y/pdb
• Related: 1I8J 1L6S
• Descriptor: PORPHOBILINOGEN SYNTHASE, ZINC ION, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: dehydratase, lyase
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 72299.81

Authors

Jaffe, E.K.,Kervinen, J.,Martins, J.,Stauffer, F.,Neier, R.,Wlodawer, A.,Zdanov, A. (deposition date: 2002-03-14, release date: 2002-04-17, Last modification date: 2023-08-16)

• Primary citation: Jaffe, E.K.,Kervinen, J.,Martins, J.,Stauffer, F.,Neier, R.,Wlodawer, A.,Zdanov, A.; Species-Specific Inhibition of Porphobilinogen Synthase by 4-Oxosebacic Acid; J.Biol.Chem., 277:19792-19799, 2002; PubMed: 11909869; DOI: 10.1074/jbc.M201486200

Experimental method

X-RAY DIFFRACTION (1.9 Å)