2B7F
Crystal structure of human T-cell leukemia virus protease, a novel target for anti-cancer design
Summary for 2B7F
Entry DOI | 10.2210/pdb2b7f/pdb |
Related PRD ID | PRD_000429 |
Descriptor | HTLV protease, (ACE)APQV(STA)VMHP peptide, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Human T-lymphotropic virus 1 |
Cellular location | Matrix protein p19: Virion . Capsid protein p24: Virion . Nucleocapsid protein p15-pro: Virion : P10274 |
Total number of polymer chains | 9 |
Total formula weight | 78776.32 |
Authors | Li, M.,Laco, G.S.,Jaskolski, M.,Rozycki, J.,Alexandratos, J.,Wlodawer, A.,Gustchina, A. (deposition date: 2005-10-04, release date: 2005-12-06, Last modification date: 2023-11-15) |
Primary citation | Li, M.,Laco, G.S.,Jaskolski, M.,Rozycki, J.,Alexandratos, J.,Wlodawer, A.,Gustchina, A. Crystal structure of human T cell leukemia virus protease, a novel target for anticancer drug design Proc.Natl.Acad.Sci.Usa, 102:18332-18337, 2005 Cited by PubMed: 16352712DOI: 10.1073/pnas.0509335102 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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